Abstract: Objective To explore the effectiveness of dual track interactive nursing intervention of three subjects on elderly patients with chronic obstructive pulmonary disease (COPD). Methods A total of 132 cases of COPD in our hospital between December,2013 and December,2015 were enrolled and were divided into intervention group and control group by simple random sampling.The control group received the routine nursing care,all the patients in this group were followed up with a t revisiting through telephone after the discharge to provide the knowledge of self-management and publicity and education;while the intervention group received dual track interactive nursing intervention of three subjects.The hospital extended care interventions track with elderly COPD patients and specialist nurses of hospital as the main body,and community care intervention track with elderly COPD patients and community nurses as the main body were built and run in the intervention group.The quality of life,SAS/SDS score in 3 months after the treatment,overall response rate and satisfaction were compared between the two groups. Results Dryprognosis of patients in the experimental group and the control group of patients with general health scores were 61.6±4.6,53.6±3.7,scores of patients in the experimental group than control group,the difference of experimental data with statistical significance (P<0.01);after intervention,there were 33 markedly effective cases,28 effective cases,5 ineffective cases in the experimental group and 23 markedly effective cases,17 effective cases,26 ineffective cases in the control group,the curative effect in the experimental group was better than that in the control group,the difference of experimental data with statistical significance (P<0.01);patients satisfaction were 97.0%,72.7% of the patients in the experimental group was higher than that of the control group experimental data differences were statistically significant (P<0.01). Conclusion The dual track interactive nursing intervention of three subjects on COPD can stimulate the patient's subjective initiative,improve psychological state and quality of life of patients.