Abstract: Objective To evaluate the characteristics and risk factors of postoperative infectious complications of laparoscopic colorectal cancer surgery in order to take targeted measures to reduce infection rates. Methods A retrospective analysis of 205 patients undertaking laparoscopic colorectal surgery from February, 2011 to February, 2016 was made to summarize the postoperative infectious complications characteristics as well as the risk factors such as the age, diabetes, lung disease, surgery time, surgical intervention, TNM stage, body mass index, blood loss, infection. Results There are 24 cases of postoperative infection following laparoscopic colorectal cancer surgery, and the infectious rate was 11.76%, among which abdominal abscess ranks the highest with a infectious rate 41.76% followed by wound infection, nosocomial pneumonia, urinary tract infections, catheter-related infections with infectious rates of 29.17%, 12.50%, 8.33%, 8.33%respectively.Compared with other kinds of infections, abdominal abscess has statistical difference (P < 0.05).The risk factors include lung disease, long operative time (> 180 min), and diabetes (P < 0.05), irrelevant to age, surgical intervention, body mass index, blood loss, TNM stage-independent (P > 0.05).The operation time, diabetes, lung disease infection after laparoscopic colorectal cancer surgery are independent risk factors (Wald values were 9.679, 10.121, 13.893;P values were 0.011, 0.014, 0.025). Conclusion Abdominal abscess is the most common infection following laparoscopic colorectal cancer surgery, while the operation time, diabetes, lung disease infection are independent risk factors which need further observation in clinical practice.