Abstract: Objective This study is aimed to explore the role of mobile health D2 C model on the prevention and management of hypertension in primary community hospital, and to study the far-reaching significance of D2 C model in the management of hypertension and chronic disease in grass-roots community. Methods Patients diagnosed with hypertension and treated at community health service center in Health Road, Jingkou District, Zhenjiang City from January to June 2014 were randomly selected.Altogether 103 cases were randomly divided into two equal groups, and group A is mobile health chronic disease management model group (59 cases) and group B is traditional management model of chronic disease control group (44 cases).Comparison of two groups of patients before and after 12 months of management and control of hypertension was made between the two groups.The awareness of disease, the incidence of complications, the degree of satisfaction and the self-management outside the hospital of patients in group A and group B were also compared. Results The systolic blood pressure, diastolic blood pressure, body mass index, fasting blood glucose and triglyceride in group A are all lower than the group B, and the differences were significant (P < 0.05).By comparing hypertension patients' awareness of hypertensive disease, the incidence of complications, the degree of satisfaction and the level of self-management outside the hospital in two groups, the chi-square values were 9.397, 11.928, 7.555, 9.936 respectively (P <0.05), the difference was statistically significant.Showing that the hypertension patients of group A had better awareness of hypertensive disease, satisfaction, self-management ability outside the hospital, and had fewer complications.The disease control effect of group A was better than the group B.The patients applied with mobile health D2 C model had better awareness of disease, satisfaction, self-management ability outside the hospital, and had fewer complications. Conclusion The application of mobile health D2 C model in the management of chronic diseases in gross-roots community strengthened the control of chronic diseases, reinforced the ability of mastering knowledge and self-management of chronic disease patients, reduced the complications, obtained satisfactory recognition of patients with mobile health, and eventually developed scientific concept of life and improved quality of life of chronic diseases patients in the community.