Abstract: Insomnia is the most common sleep disorder, which may affect the patients' emotional state and quality of life.The current treatment methods mainly include pharmacotherapy, Chinese traditional treatment and cognitive behavior therapy. Mindfulness training is the category in cognitive behavior therapy which is a kind of psychological intervention method and based on mindfulness. This type of therapy emphasized acceptance and no comments, and mainly contained three aspects:purpose, awareness and attitude. This article summarized the concept and classification of mindfulness training, mindfulness training mechanism and model, and intervention in patients with insomnia caused by different reasons, mainly covered three types:physical diseases, mental factors and primary chronic insomnia. In patients with insomnia caused by physical diseases, this article summarized the application of cancer, hypertension and part of the postoperative patients, which found that mindfulness training may improve the patients' cognitive and thinking mode, enhance sleep quality, reduce the postoperative pain intensity of patients. In patients with insomnia caused by mental factors, this paper summarized the application of depression, anxiety, psychological and occupational burnout, which found that mindfulness training may enhance individual's positive emotions, reduce perceived stress, increase total sleep time and efficiency of patients, finally improve sleep quality. In the application of primary chronic insomnia, it's concluded that mindfulness training keep patients with peaceful attitude to accept what happened now, thus reduce the average sleep time, improve sleep quality and has good long-term curative effect. In the future nursing service, the nursing workers need to pay more attention to the patients of insomnia and effectively use right mindfulness training method, in order to improve sleep quality of patients with insomnia.