Abstract: Objective At present,many medical colleges have opened or plan to establish general medicine department to train general practitioners and form general practice faculties.This paper sets the general practice department of Tongji University School of Medicine as an example and establishes the system model to guide the establishment of general practice in other areas of China,not only improve the level of primary medical care,increase the cultivation of grass-roots general practitioners,but also provide guarantee for community general teachers to develop the general practice professional. Methods Based on the empirical study,this paper introduces the multidimensional role of the cooperation between the affiliated Yangpu Hospital of Tongji University School of Medicine and other affiliated hospitals with 11 community health service centers in education,scientific research and personnel training,summarizes the characteristics and builds the framework system. Results The general practice department of Tongji University School of Medicine established the perfect organizational system,formed its own model,building the communication bridge between the community and hospital,relying on the higher medical and scientific research in affiliated hospital,and promoting the development of community through the teaching resources and training of general medicine. Conclusion s The department of general practice is to play the core guiding role of teaching,to promote the development of clinical,scientific research and teaching in the community,and to train excellent general practice teachers.The department of general practice of Tongji University School of Medicine provides modeled,which guide the establishment of general practice department in other universities.However,we should see that the general medicine is still in its infancy,opportunities and challenges exist,we must go first,analyze the problems in the construction of general medical construction in China,and draw on the good experience abroad,which develop the role of general practice.