Effects comparison of low temperature plasma radiofrequency ablation and CO₂ laser treatment on voice function of patients with laryngeal precancerous lesions

Objective To compare the effect of low temperature plasma radiofrequency ablation and CO₂ laser treatment on voice function of patients with laryngeal precancerous lesions. Methods A total of 83 patients with laryngeal precancerous lesions treated in our hospital from September 2014 to March 2018 were selected as subjects, and divided into two groups according to random number method, and 42 patients in observation group and 41 patients in control group. The control group was treated with CO₂ laser, and the observation group was treated with low temperature plasma radiofrequency ablation. After treatment, the operation time, hospitalization time, postoperative 1 day pain score (VAS score), postoperative 1 month mucosal recovery score and other surgical related indicators were compared with the postoperative 1 month fundamental frequency (F0), base frequency micro Changes in arpeggio functions such as jitter, amplitude perturbation (Shimmer), standardized noise energy (NNE), and postoperative complications. Results There was no significant difference on hospitalization time, and postoperative 1 day pain score between the observation group and the control group (all P>0.05). However, the operation time and mucosal recovery scores after surgery 1 month of observation group were significantly lower than those of control group (all P<0.05). After treatment, the F0, Jitter, Shimmer and NNE of two groups were significantly reduced (all P<0.05), However, there was no significant difference on F0 level between the two groups (P>0.05), and Jitter, Shimmer and NNE of observation group were lower than those of control group (P<0.05). There were no complications such as dysphonia, dyspnea and vocal cord adhesion in the two groups. There were no recurrence in the observation group, and 2 cases in the control group relapsed and then recovered after CO₂ laser treatment. Conclusion Compared with CO₂ laser treatment, low-temperature plasma radiofrequency ablation is more effective in the treatment of laryngeal precancerous lesions, which can effectively shorten the operation time and promote the recovery of mucosal and voice function as soon as possible.