Interaction of rumination meditations in purpose and family environment on psychological pain in elderly patients with first diagnosed bone metastasis of prostate cancer

Objective To investigate the influence of interaction of rumination meditations in purpose and family environment on psychological pain in elderly patients with first diagnosed bone metastasis of prostate cancer, so as to provide insights for further intervention approaches foe reducing the psychological pain of patients. Methods We selected 471 cases of elderly patients with first diagnosed bone metastasis of prostate cancer from December 2015 to December 2017 treated in Tangshan People's Hospital and they were divided into mild-moderate psychological pain group (n=212) and severe psychological pain group (n=259) according to the scores of distress thermometer (Distress Thermometer，DT). Meanwhile, all subjects were investigated using the Chinese Version of Event Related Rumination Inventory (C-ERRI), Family Adaptability and Cohesion Scale Ⅱ (FACES Ⅱ), Visual Analog Scale (VAS) and the general material lists. Results Univariate analysis showed that the psychological pain was statistically significant in patients age, Gleason score, pain score, ruminant meditation level and family environment on the distribution difference (all P<0.05). Multiple regression analysis displayed that after adjusting age, pain score, combined with chronic disease, low level of ruminant meditation and general family environment significantly increased the risk of severe psychological pain in patients and the OR (95%CI) respective 2.944(1.891-4.584) and 3.670(2.347-5.737). Additive interaction analysis showed that those with low level of ruminant meditations and general family environment increased the risk of severe psychological pain than those with high level of ruminant meditations and good family environment OR(95%CI)=12.252(7.660-13.691). The synergy index (SI) and attributable proportion due to interaction (AP) were 11.322(7.242-12.622) and 19.710%, respectively. Conclusion Low level of rumination meditations in purpose and general family environment are risk factors of psychological pain in patients with first diagnosed bone metastasis of prostate cancer, and there might be interaction between them.