Volume 19 Issue 1
Jan.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(1): 150-153
ZHANG Ling, LI Huai-an, ZHOU Jin. Effect of Qibai Tazi Decoction Combined with Comprehensive Nursing Based on 5E Concept on the Clinical Efficacy and Inflammatory Factors of Jellyfish Acute Dermatitis[J]. Chinese Journal of General Practice, 2021, 19(1): 150-153. doi: 10.16766/j.cnki.issn.1674-4152.001753
Citation: ZHANG Ling, LI Huai-an, ZHOU Jin. Effect of Qibai Tazi Decoction Combined with Comprehensive Nursing Based on 5E Concept on the Clinical Efficacy and Inflammatory Factors of Jellyfish Acute Dermatitis[J]. Chinese Journal of General Practice, 2021, 19(1): 150-153. doi: 10.16766/j.cnki.issn.1674-4152.001753
shu

Effect of Qibai Tazi Decoction Combined with Comprehensive Nursing Based on 5E Concept on the Clinical Efficacy and Inflammatory Factors of Jellyfish Acute Dermatitis

doi: 10.16766/j.cnki.issn.1674-4152.001753

  • Qinhuangdao Hospital of traditional Chinese medicine, Qinhuangdao, Hebei 066000, China

Funds:

 20180932

  • Received Date: 2019-12-05
    Available Online: 2022-02-19
    Abstract
  •   Objective  To explore the effect of external application of Qibai Tazi Decoction combined with comprehensive nursing based on 5E concept on the curative effect and serum inflammatory factors of jellyfish acute dermatitis.  Methods  A total of 157 patients with acute dermatitis were divided into standard group (79 cases) and 5E group (78 cases). Both groups were given external application of Qibai Tazi Decoction, standard group was given standardized nursing management, and 5E group was given 5E comprehensive nursing intervention. Three days later, the efficacy, pain time, skin lesions, swelling time, histamine, pain causing substances, IL-6, IL-8, IL-10, water content and oil content in epidermis of the two groups were compared, and then the effect of the two groups was evaluated.  Results  The onset time of 5E group was faster than that of the standard group (P < 0.05). After treatment, histamine and pain causing substance in the two groups decreased compared with that before treatment (P < 0.01). The effect of 5E group was significantly better than that of the standard group (all P < 0.05). The expressions of IL-6, IL-8 and IL-10 in the two groups increased before and after treatment. The expressions of IL-6 and IL-8 in the two groups decreased and the expression of IL-10 increased (all P < 0.05). The 5E effect of the two groups was better than that of the standard group (P < 0.05). There was interaction effect between the two groups at the time point (all P < 0.05). The water content and oil content of epidermis in the two groups decreased before treatment, and the above indexes increased in the two groups after treatment (all P < 0.01), and the improvement of 5E was better than that in the standard group (P < 0.05).  Conclusion  The external application of Qibai Tazi Decoction combined with 5E comprehensive nursing can improve the clinical effect, the allergic state and inflammatory response of skin, and the local skin state.

     

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