Volume 19 Issue 2
Feb.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(2): 189-192, 259
YU Ru, LIANG Qi-sheng, LIU Lei, FU Wei, JIANG Yu-yu, WANG Kang-wu. Study on the correlation between cerebral oxygen saturation and PEEP level of thoracoscopic elderly patients with lung cancer[J]. Chinese Journal of General Practice, 2021, 19(2): 189-192, 259. doi: 10.16766/j.cnki.issn.1674-4152.001764
Citation: YU Ru, LIANG Qi-sheng, LIU Lei, FU Wei, JIANG Yu-yu, WANG Kang-wu. Study on the correlation between cerebral oxygen saturation and PEEP level of thoracoscopic elderly patients with lung cancer[J]. Chinese Journal of General Practice, 2021, 19(2): 189-192, 259. doi: 10.16766/j.cnki.issn.1674-4152.001764
shu

Study on the correlation between cerebral oxygen saturation and PEEP level of thoracoscopic elderly patients with lung cancer

doi: 10.16766/j.cnki.issn.1674-4152.001764

  • Department of Anesthesiology, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

 KJ2019A0366

  • Received Date: 2020-06-21
    Available Online: 2022-02-19
    Abstract
  •   Objective  To investigate the correlation between positive end-expiratory pressure (PEEP) and cerebral oxygen saturation (rSO2) in elderly patients with thoracoscopic lung cancer.  Methods  A total of 60 elderly patients with thoracoscopic lobectomy from October 2019 to February 2020 were selected from the First Affiliated Hospital of Bengbu Medical College. They were divided into group A, group B and group C according to the order of admission, with 20 patients in each group. In the case of one-lung ventilation, tidal volume (VT) was set at 5 mL/kg in the 3 groups, and PEEP was set at 0, 5, and 10 cm H2O in the A, B, and C groups, respectively. Pulse oxygen saturation (SpO2), airway peak pressure (Ppeak), pulmonary dynamic compliance (Cdyn), oxygen partial pressure (PaO2) and cerebral oxygen saturation values (rSO2) were observed and recorded at five time points after anesthesia induction: 15 min (T0), 10 min (T1), 30 min (T2), 60 min (T3), and 20 min (T4) after recovery of bilateral ventilation.  Results  The minimum and average values of rSO2 in group B was significantly higher than that in group A and C (all P < 0.05), and the maximum percentage of rSO2 in group B was significantly lower than that in group A and C (all P < 0.05). At the time point T2-T4, rSO2 in group B was higher than that in group A and C, with group C higher than that in group A (all P < 0.05). At time point T1-T4, Ppeak in group B was lower than that in group A and C (all P < 0.05). Cydn of group B at time T1-T4 was higher than that of group A, and that of group B at time T1 was higher than that of group A and C (all P < 0.05). PaO2 in group B and C was significantly higher than that in group A at T2-T4 (all P < 0.05), and SpO2 showed no statistically significant difference between the three groups at T0-T4 (all P>0.05).  Conclusion  There was a correlation between brain oxygen saturation value and PEEP level during single lung ventilation in elderly patients undergoing thoracoscopic lung resection for lung cancer, and PEEP level at 5 cm H2O had a better rSO2 level.

     

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