Volume 19 Issue 2
Feb.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(2): 209-211, 251
CHEN Li-peng, DU Li-yun, ZHENG Pei-fen. The effectiveness evaluation of polyethylene glycol electrolyte solution in bowel preparation in divided doses of two days for elderly constipation patients[J]. Chinese Journal of General Practice, 2021, 19(2): 209-211, 251. doi: 10.16766/j.cnki.issn.1674-4152.001769
Citation: CHEN Li-peng, DU Li-yun, ZHENG Pei-fen. The effectiveness evaluation of polyethylene glycol electrolyte solution in bowel preparation in divided doses of two days for elderly constipation patients[J]. Chinese Journal of General Practice, 2021, 19(2): 209-211, 251. doi: 10.16766/j.cnki.issn.1674-4152.001769
shu

The effectiveness evaluation of polyethylene glycol electrolyte solution in bowel preparation in divided doses of two days for elderly constipation patients

doi: 10.16766/j.cnki.issn.1674-4152.001769

  • Digestive System Department, Zhejiang Hospital, Hangzhou, Zhejiang 310012, China

Funds:

 2020KY397

  • Received Date: 2020-03-12
    Available Online: 2022-02-19
    Abstract
  •   Objective  To compare and analyze the bowel preparation effect and patient tolerance to different regimens of elderly constipation patients taking compound polyethylene glycol electrolyte powder in several doses 1 day before colonoscopy and on the same day as taking the same dose once 6 hours before colonoscopy.  Methods  According to the diagnostic criteria of Roman Ⅳ constipation, 150 mild to moderate constipation patients aged 60~85 years who were to undergo painless colonoscopy were selected and randomly divided into A, B and C groups, with 50 people in each group. Group A took 1 L of compound PEGYlated electrolyte powder at 15:00 1 day before the examination, and 2 L 6 hours before the examination. Group B received 3 L of compound PEGYlated electrolyte powder 6 hours before the examination. In group C, 1 L of compound PEGYlated electrolyte powder was taken at 20:00 1 day before the examination, and 2 L was taken 6 hours before the examination. The colonoscopy time point and diet of patients in the 3 groups were the same. Bowel cleanliness was assessed using the Boston Bowel Preparation Scale (BBPS), and scope-forward time was recorded. Both were recorded singly and blindly by the same endoscope physician. Patients' tolerance to different bowel preparation plans and adverse reactions were obtained through questionnaire survey.  Results  All patients completed bowel preparation and colonoscopy well. The average scope-forward time of the 3 groups were (4.34±1.29) min, (4.59±1.32) min, (4.45±1.50) min, and the good and good rates of bowel preparation quality after BBPS score were 95.7%, 93.9%, and 95.9%, respectively, with no statistically significant difference (all P>0.05). The bowel preparation tolerance rate in group A and Group C were 85.11% and 79.59%, both of which were better than 62.22% in group B. The incidence of adverse reactions in group A was the lowest (31.91%, 57.14% and 93.88%), and the results were statistically significant (all P < 0.05).  Conclusion  There is no difference in the effect of bowel preparation between the next day by several times of oral complex polyethylene glycol electrolyte powder and conventional colonoscopy one-time 6 hours before taking the same dose drugs, but the next day taking has better tolerance in patients with senile constipation, less adverse reaction, especially in the afternoon to take 1 day in advance and influence to sleep less, worth clinical promotion.

     

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    • References(17)
  • [1]
    肖静, 于子涵. 无痛胃肠镜在诊疗消化道疾病中的安全性及应用价值[J]. 中国疗养医学, 2017, 26(1): 56-58. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGLX201701025.htm
    [2]
    MAIDA M, MORREALE G, SINAGRA E, et al. Quality measures improving endoscopic screening of colorectal cancer: a review of the literature [J]. Expert Rev Anticancer Ther, 2019, 19(3): 223-235. doi: 10.1080/14737140.2019.1565999
    [3]
    GUO R, WANG Y J, LIU M, et al. The Effect of Quality of Segmental Bowel Preparation on Adenoma Detection Rate [J]. BMC Gastroenterol, 2019, 19(1): 119. doi: 10.1186/s12876-019-1019-8
    [4]
    占俊, 汤进芝, 汪文生, 等. 不同剂型聚乙二醇电解质在结肠镜检查前肠道准备中的应用比较[J]. 中华全科医学, 2020, 18(8): 1283-1286. https://www.cnki.com.cn/Article/CJFDTOTAL-SYQY202008011.htm
    [5]
    张智, 葛兆霞, 邓小岚. 老年患者结肠镜检查前不同肠道准备方法的效果对比[J]. 中华现代护理杂志, 2017, 23(14): 1829-1832. doi: 10.3760/cma.j.issn.1674-2907.2017.14.001
    [6]
    HORTON N, GARBER A, HASSON H, et al. Impact of single-vs. split-dose low-volume bowel preparations on bowel movement kinetics, patient inconvenience, and polyp detection: a prospective trial[J]. Am J Gastroenterol, 2016, 111(9): 1330-1337. doi: 10.1038/ajg.2016.273
    [7]
    RUSSO M, STRISCIUGLIO C, SCARPATO E, et al. Functional chronic constipation: rome Ⅲ criteria versus rome iv critiera [J]. J Neurogastroenterol Motil, 2019, 25(1): 123-128. doi: 10.5056/jnm18035
    [8]
    VAZQUEZ ROQUE M, BOURAS E P. Epidemiology and management of chronic constipation in elderly patients [J]. Clin Interv Aging, 2015, 10: 919-930. http://www.dovepress.com/getfile.php?fileID=25284
    [9]
    中华医学会老年医学分会, 中华老年医学杂志编辑委员会. 老年人慢性便秘的评估与处理专家共识[J]. 中华老年医学杂志, 2017, 36(4): 371-381. doi: 10.3760/cma.j.issn.0254-9026.2017.04.007
    [10]
    SULZ M C, KRÖGER A, PRAKASH M, et al. Meta-analysis of the effect of bowel preparation on adenoma detection: early adenomas affected stronger than advanced adenomas[J]. PLoS One, 2016, 11(6): e0154149. doi: 10.1371/journal.pone.0154149
    [11]
    中华医学会消化内镜学分会. 中国消化内镜诊疗相关肠道准备指南(草案)[J]. 胃肠病学, 2014, 19(6): 354-356. doi: 10.3969/j.issn.1008-7125.2014.06.009
    [12]
    ALVAREZ-GONZALEZ M A, PANTALEON M A, FLORES-LE ROUX J A, et al. Randomized clinical trial: a normocaloric low-fiber diet the day before colonoscopy is the most effective approach to bowel preparation in colorectal cancer screening colonoscopy [J]. Dis Colon Rectum, 2019, 62(4): 491-497. doi: 10.1097/DCR.0000000000001305
    [13]
    WALTER J, FRANCIS G, MATRO R, et al. The impact of diet liberalization on bowel preparation for colonoscopy [J]. Endosc Int Open, 2017, 5(4): 253-260. doi: 10.1055/s-0043-101694
    [14]
    KANG M K, JANG B L, PARK J S, et al. Efficacy of ramosetron in combination with polyethylene glycol of preparing for a colonoscopy [J]. Yeungnam Univ J Med, 2019, 36(2): 99-104. doi: 10.12701/yujm.2019.00080
    [15]
    LÓPEZ S, VARGAS C, LÓPEZ C. Effectiveness and tolerability of low volume bowel cleansing polyethylene glycol solution for colonoscopy [J]. Rev Med Chil, 2019, 147(8): 977-982. doi: 10.4067/S0034-98872019000800977
    [16]
    樊波. 聚乙二醇电解质口服溶液在老年患者结肠镜检查前肠道准备中的应用[J]. 中国药物与临床, 2019, 19(16): 2795-2796. https://www.cnki.com.cn/Article/CJFDTOTAL-YWLC201916049.htm
    [17]
    ZHANG S, LI M, ZHAO Y, et al. 3-L split-dose is superior to 2-L polyethylene glycol in bowel cleansing in Chinese population: a multicenter randomized, controlled trial [J]. Medicine (Baltimore), 2015, 94(4): e472. doi: 10.1097/MD.0000000000000472
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