Volume 19 Issue 2
Feb.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(2): 241-244
CHEN Qiong, DING Zhou-zhi, LIU Na-na, PENG Wan-sheng. Analysis on clinical characteristics and laboratory examination of Epstein-Barr virus infection in hospitalized children at different age stages[J]. Chinese Journal of General Practice, 2021, 19(2): 241-244. doi: 10.16766/j.cnki.issn.1674-4152.001777
Citation: CHEN Qiong, DING Zhou-zhi, LIU Na-na, PENG Wan-sheng. Analysis on clinical characteristics and laboratory examination of Epstein-Barr virus infection in hospitalized children at different age stages[J]. Chinese Journal of General Practice, 2021, 19(2): 241-244. doi: 10.16766/j.cnki.issn.1674-4152.001777
shu

Analysis on clinical characteristics and laboratory examination of Epstein-Barr virus infection in hospitalized children at different age stages

doi: 10.16766/j.cnki.issn.1674-4152.001777

  • Department of Pediatrics, the first Affiliated Hospital of Bengbu Medical Collage, Bengbu, Anhui 233004, China

Funds:

 KJ2019A0365

  • Received Date: 2020-06-10
    Available Online: 2022-02-19
    Abstract
  •   Objective  To explore the clinical features and in laboratory examination of children with EBV infection at different age stages.  Methods  The clinical data of 153 case hospitalized children with EBV infection from January 2012 to January 2020 in the First Affiliated Hospital of Bengbu Medical Collage were collected. All Patients were divided three groups, the infant and toddler period group (1 month to 3 years old, 52 cases), the preschool period group (3-7 years old, 57 cases), and the school-age period group (7-14 years old, 44 cases). The general data, clinical manifestations and laboratory examination results of children in each group were analyzed, and the characteristics were found and summarized.  Results  The onset season was dominated by spring and summer, and high in summer and low in winter, respectively, 66 cases (43.1%) in summer, 32 cases (20.9%) in autumn, 43 cases (28.1%) in spring, and 12 cases (7.8%) in winter. In the spectrum of disease, the infectious mononucleosis predominates had 62 case (40.5%). Diseases were more diverse in the infant and toddler period group, and they had high incidence of respiratory diseases such as bronchopneumonia and bronchitis, some rare cases of parotid gland enlargement. In clinical manifestation, there were 25 cases of cough (48.1%) and 14 cases of rash (26.9%) in the infant and toddler period group, higher than those in the preschool period group and school-age group (all P < 0.05). The lymphadenectasis in preschool period group had 36 case (63.2%) and in the school-age group has 26 case (59.1%), higher than those in the infant and toddler period group (all P < 0.05). The proportion of apyrexia in the infant and toddler period group had 18 cases (72.0%), higher than that in the other two groups, and hyperpyrexia had 7 cases (16.7%), lower than that in the other two groups (all P < 0.05). In the laboratory examination, there were 93 case patients increased in ALT, the ALT level of the infant and toddler period group was lower than that of the preschool period group. The difference was statistically significant (all P < 0.05).  Conclusion  Children who infect EBV at different ages are not totally identical in disease spectrum distribution, clinical manifestation and laboratory examination. So, mastering the characteristics of diseases at different age stages is conducive to early detection, early diagnosis and early treatment of diseases.

     

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