Volume 19 Issue 2
Feb.  2021
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LI Qiong-fang, TAO Qun, YIN Zong-zhi. Value of pelvic magnetic resonance imaging and intraoperative frozen section in diagnosing myometrial invasion in patients with endometrial cancer[J]. Chinese Journal of General Practice, 2021, 19(2): 287-289. doi: 10.16766/j.cnki.issn.1674-4152.001790
Citation: LI Qiong-fang, TAO Qun, YIN Zong-zhi. Value of pelvic magnetic resonance imaging and intraoperative frozen section in diagnosing myometrial invasion in patients with endometrial cancer[J]. Chinese Journal of General Practice, 2021, 19(2): 287-289. doi: 10.16766/j.cnki.issn.1674-4152.001790

Value of pelvic magnetic resonance imaging and intraoperative frozen section in diagnosing myometrial invasion in patients with endometrial cancer

doi: 10.16766/j.cnki.issn.1674-4152.001790
Funds:

 KJ2018A0188

  • Received Date: 2020-08-16
    Available Online: 2022-02-19
  •   Objective  To analyse the results of preoperative pelvic magnetic resonance imaging (MRI), intraoperative rapid frozen section (FS), and postoperative paraffin pathology in diagnosing myometrial invasion in patients with endometrial cancer, as well as to compare the diagnostic value of pelvic MRI and FS in the myometrial invasion of endometrial cancer.  Methods  Through retrospective analysis, 89 patients with stage I endometrial cancer diagnosed by paraffin after operation were selected from Chaohu Hospital of Anhui Medical University from January 2009 to January 2017, and their sociodemographic and clinical data were collected. Results of preoperative pelvic MRI and intraoperative FS on myometrial invasion and deep myometrial invasion were compared with those of postoperative paraffin pathology, respectively. The sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV) were calculated to compare the diagnostic value of preoperative pelvic MRI and intraoperative FS in myometrial invasion.  Results  The sensitivity (86.76% vs. 63.24%), accuracy (84.27% vs. 62.92%), and NPV (64.00% vs. 34.21%) of intraoperative FS for myometrial invasion were higher than those of preoperative MRI (P < 0.05). Similarly, the specificity (100.00% vs. 90.41%), accuracy (95.51% vs. 86.52%), and PPV (100.00% vs. 61.11%) of intraoperative FS for deep myometrial invasion were higher than those of preoperative MRI (all P < 0.05).  Conclusion  For patients with endometrial cancer whose myometrial invasion is tested negative by preoperative MRI, intraoperative rapid FS examination should be performed to further evaluate myometrial invasion with increased accuracy.

     

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