Volume 19 Issue 4
Apr.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(4): 550-553
LIU Dong-dong, SHEN Jian, HUANG Si-yuan, WANG Hai-lao. Analysis of factors related to pulmonary infection after radical resection of lung cancer[J]. Chinese Journal of General Practice, 2021, 19(4): 550-553. doi: 10.16766/j.cnki.issn.1674-4152.001858
Citation: LIU Dong-dong, SHEN Jian, HUANG Si-yuan, WANG Hai-lao. Analysis of factors related to pulmonary infection after radical resection of lung cancer[J]. Chinese Journal of General Practice, 2021, 19(4): 550-553. doi: 10.16766/j.cnki.issn.1674-4152.001858
shu

Analysis of factors related to pulmonary infection after radical resection of lung cancer

doi: 10.16766/j.cnki.issn.1674-4152.001858

  • Department of Cardio-thoracic Surgery, Zhejiang Provincial People's Hospital/People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, China

Funds:

 2020KY009

 LY20H010005

  • Received Date: 2020-07-30
    Available Online: 2022-02-16
    Abstract
  •   Objective  To investigate the factors influencing pulmonary infection after radical resection of lung cancer.  Methods  Eighty-two patients who underwent radical resection of lung cancer in Department of Cardio-thoracic Surgery in Zhejiang Provincial People's Hospital/People's Hospital of Hangzhou Medical College were selected from February 2018 to February 2020. Eighty-two cases of lung cancer, according to whether the lung infection can be divided into pulmonary infection (23 cases) and non-pulmonary infection group (59 cases). The general clinical data of the patients were collected. The factors related to lung cancer that affect postoperative pulmonary infection after radical cure were analysed.  Results  The incidence of postoperative pulmonary infection was 28.05%. Univariate analysis revealed no significant correlation among gender, hypertension, preoperative pulmonary function, lobectomy site, pathological type, pathological stage and postoperative pulmonary infection (all P>0.05). Age (≥60 years old), VAS score of incision (4-10 points), long-term smoking history, combined chronic obstructive pulmonary disease (COPD), diabetes mellitus (DM), operation duratiion (≥3 h), operation method (i.e., traditional thoracotomy), mechanical ventilation time (≥6 h) and indwelling time of thoracic drainage tube (≥4 days) were closely correlated with pulmonary infection (all P < 0.05). Logistic multivariate analysis showed that age (≥60 years old), long operation duration (≥3 h), combined COPD, DM, operation method (traditional thoracotomy), long-term smoking history, VAS score of incision (4-10 points) and long duration of pleural indwelling drainage (≥4 days) were independent influencing factors for postoperative pulmonary infection in patients undergoing radical resection of lung cancer (all P < 0.05).  Conclusion  The incidence of postoperative pulmonary infection is high in lung cancer patients after radical resection pulmonary infection. The risk factors of postoperative pulmonary infection in patients with lung cancer after radical resection are age (≥60 years old), long operation duration (≥3 h), with COPD, with DM (traditional surgery), surgical way, long-term smoking history, VAS score of incision (4-10 points) and long chest drainage timeline (≥4 days). These risk factors should be paid more attentions so as to reduce the incidence of postoperative pulmonary infection.

     

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