Volume 19 Issue 4
Apr.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(4): 564-567
HUANG Xin, KONG Hong-jiao, ZHU Ming-na, HUANG Lin-kai, YANG Yu, REN Xiao-ying, ZHANG Hui. Analysis of different gender-related factors and observation of the safety of enhanced external counterpulsation in elderly patients with heart failure and preserved ejection fraction[J]. Chinese Journal of General Practice, 2021, 19(4): 564-567. doi: 10.16766/j.cnki.issn.1674-4152.001862
Citation: HUANG Xin, KONG Hong-jiao, ZHU Ming-na, HUANG Lin-kai, YANG Yu, REN Xiao-ying, ZHANG Hui. Analysis of different gender-related factors and observation of the safety of enhanced external counterpulsation in elderly patients with heart failure and preserved ejection fraction[J]. Chinese Journal of General Practice, 2021, 19(4): 564-567. doi: 10.16766/j.cnki.issn.1674-4152.001862
shu

Analysis of different gender-related factors and observation of the safety of enhanced external counterpulsation in elderly patients with heart failure and preserved ejection fraction

doi: 10.16766/j.cnki.issn.1674-4152.001862
  • 1.

    Department of Cardiology, the Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China

Funds:

 201402019

 201601008

  • Received Date: 2020-06-15
    Available Online: 2022-02-16
    Abstract
  •   Objective  This study aimed to explore the gender-related factors and clinical characteristics of elderly patients with heart failure and preserved ejection fraction (HFpEF) and compare the safety of enhanced external counterpulsation (EECP) in the treatment of elderly patients with HFpEF of different genders.  Methods  A total of 200 elderly patients (≥65 years old) who received EECP treatment at the Second Affiliated Hospital of Zhengzhou University from January 2019 to January 2020 and were diagnosed with HFpEF were divided into the male group (n=88) and female group (n=112) according to gender. General clinical data (age, BMI, smoking history and past history), inspection data [NYHA cardiac function grade, renal function, left ventricular ejection fraction (LVEF) and Brain Natriuretic Peptide], BNP were recorded, and the adverse reactions of the elderly HFpEF patients of different gender were compared after EECP treatment.  Results  The number of elderly women with HFpEF was significantly higher than that of men (56% and 44%, P < 0.05), and the age of disease, BMI and LVEF were greater than that of men (all P < 0.05). There are more patients in the NYHA heart function class Ⅲ and Ⅳ in the female group than in the male group; the number of elderly male HFpEF patients with smoking history was greater than that of females (P < 0.05), and there are more patients in the NYHA cardiac function classification of grade Ⅰ and Ⅱ in the male group than in the female group. Analysis of related factors showed that obesity, atrial fibrillation, hypertension and LVEF have a strong correlation with the female group (all P < 0.05); smoking history and hyperlipidaemia have a strong correlation with the male group (P < 0.05). The incidence of adverse reactions in different gender groups of EECP treatment for HFpEF was not statistically significant (7.95% vs. 9.82%, P > 0.05).  Conclusion  Gender differences in the relevant factors of elderly HFpEF patients are found, and the clinical characteristics of elderly female HFpEF patients are unique, but EECP has the same safety for elderly HFpEF patients of different gender.

     

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