Volume 19 Issue 5
May  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(5): 778-781
YOU Jia-yun, YU Chao-wen, NIE Zhong-lin, GAO Yong, LU Ran, WANG Qiang, WANG Chen-meng. Clinical characteristics and treatment of penetrating aortic ulcer[J]. Chinese Journal of General Practice, 2021, 19(5): 778-781. doi: 10.16766/j.cnki.issn.1674-4152.001915
Citation: YOU Jia-yun, YU Chao-wen, NIE Zhong-lin, GAO Yong, LU Ran, WANG Qiang, WANG Chen-meng. Clinical characteristics and treatment of penetrating aortic ulcer[J]. Chinese Journal of General Practice, 2021, 19(5): 778-781. doi: 10.16766/j.cnki.issn.1674-4152.001915
shu

Clinical characteristics and treatment of penetrating aortic ulcer

doi: 10.16766/j.cnki.issn.1674-4152.001915

  • Department of Vascular Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

 201904a07020020

  • Received Date: 2020-09-25
    Available Online: 2022-02-16
    Abstract
  •   Objective  To analyse and summarise the clinical characteristics of patients with penetrating aortic ulcer (PAU) and the choice of treatment.  Methods  Clinical data of 32 PAU patients admitted to the Vascular Surgery Department of the First Affiliated Hospital of Bengbu Medical College from January 2016 to November 2019 were retrospectively analysed, including 12 cases in the conservative treatment group and 20 cases in the endovascular aneurysm repair (EVAR) group. The clinical characteristics and therapeutic effects of the two groups were analysed.  Results  The hospital time of the patients in the EVAR group was short compared with the conservative treatment group (all P < 0.05). The D-dimer level, ulcer diameter, depth of the ulcer and concurrent aortic intramural hematoma (intramural hematoma, IMH) of the EVAR group were higher compared with those of the conservative treatment group, and the differences were statistically significant (all P < 0.05). No statistically significant differences were observed in the other areas (all P>0.05). Recent follow-up on new conservative treatment group patients showed that the incidence of aortic dissection was higher than that in the EVAR group, and the difference was statistically significant (P < 0.05). Long-term follow-up showed that the risk of ulcer increases for the two groups. The incidence of new aortic dissection for the EVAR group was slightly lower than that for the conservative treatment group, but there was no statistically significant difference (P=0.089, 0.089). Other indicators had no statistically significant differences (all P>0.05).  Conclusion  EVAR is a safe and effective method in the treatment of PAU as it can reduce the incidence of recent aortic dissection compared with the conservative treatment. EVAR is recommended for patients with persistent pain symptoms, combined IMH and signs of aortic rupture.

     

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