Volume 19 Issue 5
May  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(5): 833-837
ZHANG Jia-ling, GE Hui, WU Wen-juan. Diagnostic value of contrast-enhanced LI-RADS classification criteria in hepatocellular carcinoma[J]. Chinese Journal of General Practice, 2021, 19(5): 833-837. doi: 10.16766/j.cnki.issn.1674-4152.001929
Citation: ZHANG Jia-ling, GE Hui, WU Wen-juan. Diagnostic value of contrast-enhanced LI-RADS classification criteria in hepatocellular carcinoma[J]. Chinese Journal of General Practice, 2021, 19(5): 833-837. doi: 10.16766/j.cnki.issn.1674-4152.001929
shu

Diagnostic value of contrast-enhanced LI-RADS classification criteria in hepatocellular carcinoma

doi: 10.16766/j.cnki.issn.1674-4152.001929
  • 1.

    Department of Medical Ultrasound, the Third People's Hospital of Bengbu, Affiliated to Bengbu Medical College, Bengbu, Anhui 233000, China

Funds:

 kj2017A234

  • Received Date: 2020-08-25
    Available Online: 2022-02-16
    Abstract
  •   Objective  The aim of this study was to explore the diagnostic efficacy of the Contrast-enhanced ultrasound liver image report and data system (LI-RADS) for hepatocellular carcinoma (HCC) and evaluate its application value in HCC.  Methods  The ultrasound contrast data of 163 focal liver lesions in 150 patients with high risk factors for HCC who were treated at the Third People's Hospital of Bengbu from September 2018 to June 2020 were selected, and four physicians with more than 5 years of experience in contrast-enhanced liver ultrasound were divided into two groups according to the standard of conventional contrast-enhanced ultrasound and the LI-RADS classification standard of contrast-enhanced ultrasound to diagnose 163 lesions. Using pathological results as the gold standard, we calculated the sensitivity, specificity, positive and negative predictive value, and diagnostic coincidence rate, and draw ROC curve to compare the diagnostic efficacy of the two groups.  Results  One hundred and sixty-three lesions were confirmed pathologically for 122 HCC, 16 for non-HCC malignant lesions, and 25 for benign lesions. The coincidence rate of conventional diagnosis of HCC was 87.1% (142/163), and the area under the curve (AUC) was 85.7%. In the LI-RADS classification, LR-5 has the highest specificity (95.1%) but low sensitivity (72.1%) in the diagnosis of HCC. If LR-4+LR-5 were diagnosed as HCC, its sensitivity (98.4%, 120/122), specificity (82.9%, 34/41), diagnostic coincidence rate (94.5%, 154/163) and AUC (90.6%) were all higher than the conventional methods. The diagnostic accuracy of classification method is better than that of conventional method, and the difference between the two groups were statistically significant (χ2 =4.654, P=0.031).  Conclusion  The LI-RADS classification standard of contrast-enhanced ultrasound can improve the diagnostic coincidence rate of HCC and has high diagnostic value.

     

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