Volume 19 Issue 6
Jun.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(6): 904-907
SONG Yu-rong, ZHAN Lei, SUN Li. Effects of epidural labour analgesia on delivery process, delivery mode and postpartum depression[J]. Chinese Journal of General Practice, 2021, 19(6): 904-907. doi: 10.16766/j.cnki.issn.1674-4152.001946
Citation: SONG Yu-rong, ZHAN Lei, SUN Li. Effects of epidural labour analgesia on delivery process, delivery mode and postpartum depression[J]. Chinese Journal of General Practice, 2021, 19(6): 904-907. doi: 10.16766/j.cnki.issn.1674-4152.001946
shu

Effects of epidural labour analgesia on delivery process, delivery mode and postpartum depression

doi: 10.16766/j.cnki.issn.1674-4152.001946

  • Department of Obstetrics and Gynecology, the Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230601, China

Funds:

 81802586

  • Received Date: 2020-12-11
    Available Online: 2022-02-16
    Abstract
  •   Objective  To analyse the effects of epidural labor analgesia (LA) on the process and mode of delivery and the risk of postpartum depression (PPD) by comparing labour-related indicators and postpartum depressive symptoms between LA-treated and non-analgesia groups.  Methods  In the prospective cohort study, 556 full-term parturient women admitted to the Second Affiliated Hospital of Anhui Medical University from November 2019 to February 2020 were included in the study. Their socio-demographic and delivery-related data were collected. Depressive symptoms were evaluated using the Edinburgh Postpartum Depression Scale (EPDS) 42 days after delivery. The first and second stages of labour, mode of delivery, forceps delivery, use of oxytocin, amount of postpartum hemorrhage two hours after delivery and neonatal Apgar and EPDS scores were compared among the early stage (A1), late stage (A2) epidural analgesia and non-analgesia (C) groups.  Results  The times of the first and second stages of labour and the proportion of the use of the Caesarean section and oxytocin in groups A1 and A2 were significantly higher than those in group C (all P < 0.05). Maternal blood loss in groups A1 and A2 was lower than that in group C (all P < 0.05). The EPDS scores and the prevalence rate of PPD in groups A1 and A2 were lower than those in group C (all P < 0.05). After Bonferroni correction, there was no significant difference in cesarean section rate between A1 group and C group (P>0.017), but there was still significant difference between any other two groups (all P < 0.017). Multivariate logistic regression analysis showed that LA was a protective factor for the occurrence of PPD after pregnancy-related confounding factors were controlled (OR=0.447, 95% CI: 0.245-0.818; P=0.009).  Conclusion  Epidural LA can prolong the stages of labour in parturient women but can reduce the risk of 6 week PPD. Overall, this treatment mode is safe for mothers and newborns and suitable for clinical use.

     

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