Volume 19 Issue 6
Jun.  2021
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(6): 954-958
HUANG Zhao-hui, ZHANG Yue, GUOLIU Run-nan, HU Lin-feng, FENG Fang, ZHAI Qian, FANG Liang, LIU Kai. Initiation of antiretroviral treatment among HIV-infected pregnant women and associated factors[J]. Chinese Journal of General Practice, 2021, 19(6): 954-958. doi: 10.16766/j.cnki.issn.1674-4152.001959
Citation: HUANG Zhao-hui, ZHANG Yue, GUOLIU Run-nan, HU Lin-feng, FENG Fang, ZHAI Qian, FANG Liang, LIU Kai. Initiation of antiretroviral treatment among HIV-infected pregnant women and associated factors[J]. Chinese Journal of General Practice, 2021, 19(6): 954-958. doi: 10.16766/j.cnki.issn.1674-4152.001959
shu

Initiation of antiretroviral treatment among HIV-infected pregnant women and associated factors

doi: 10.16766/j.cnki.issn.1674-4152.001959

  • Anhui Provincial Center for Women And Child Health, Hefei, Anhui 230000, China

Funds:

 2018FYH016

  • Received Date: 2020-09-25
    Available Online: 2022-02-16
    Abstract
  •   Objective  The proportion of antiretroviral treatment among HIV-infected pregnant women is an important evaluation index for the program of china's women development. However, the anticipated goals of such programs are difficult to achieve in Anhui province. This paper aimed to analyse the proportion of antiretroviral treatment among HIV-infected pregnant women and related influencing factors and provide support for promoting the proportion.  Methods  Data were abstracted from an information system for the prevention of mother-to-child transmission (PMTCT) of acquired immunodeficiency syndrome (AIDS), hepatitis B and syphilis from 2004 to 2020. The data included basic information about the husbands or sexual partners of the pregnant women and initiation of antiretroviral treatment (ART). Pearson chi-square test and Poisson regression model were used in analysing the data.  Results  A total of 834 HIV-infected pregnant women were reported in Anhui province, with an average age of 28.65±6.39 years. The initiating ART rate among HIV-infected pregnant women increased from 57% (2004-2010) to 95% (2020), χ2=47.658, P < 0.001. The result of Poisson regression model revealed that the HIV-infected pregnant women diagnosed before pregnancy (95% CI: 2.91-9.13), during pregnancy (95% CI: 2.85-8.97) and during the intrapartum period (95% CI: 1.00-3.64) were less likely to initiate ART than those diagnosed in the postpartum period.  Conclusion  Our results suggest that the confirmed time of HIV can be advanced by strengthening the management of pregnant women and useful in alleviating the effect of the PMTCT of AIDS.

     

    • FullText(HTML)
  • loading
    • References(20)
  • [1]
    黄磊, 李中杰, 王福生, 等. 新中国成立70年来在传染病防治领域取得的成就与展望[J]. 中华全科医学, 2019, 17(10): 1615-1618. https://www.cnki.com.cn/Article/CJFDTOTAL-SYQY201910001.htm
    [2]
    中国疾病预防控制中心. 全国艾滋病、性病、丙肝综合防治数据信息年报[R]. 北京: 中国疾病预防控制中心, 2017: 102.
    [3]
    田一梅, 梁梅馨, 宋俊敏, 等. 2009—2018年深圳市HIV阳性孕产妇特点及母婴阻断效果分析[J]. 中国艾滋病性病, 2020, 26(3): 264-267. https://www.cnki.com.cn/Article/CJFDTOTAL-XBYA202003010.htm
    [4]
    葛宪民, 杨文敏, 沈智勇, 等. HIV阳性母亲接受预防艾滋病母婴传播对其所生18月龄儿童体格发育的影响[J]. 中华流行病学杂志, 2020, 41(3): 354-355, 357. doi: 10.3760/cma.j.issn.0254-6450.2020.03.014
    [5]
    宋歌, 赵兴云, 庞艳华, 等. HIV母婴传播阻断综合措施与效果评价[J]. 中国性科学, 2019, 28(5): 102-104. https://www.cnki.com.cn/Article/CJFDTOTAL-XKXZ201905033.htm
    [6]
    WHO. Global guidance on criteria and processes for validation: elimination of mother-to-child transmission (EMTCT) of HIV and Syphillis [R]. Geneva: World Health Organizationg, 2017.
    [7]
    GARCA-DELTORO M. Rapid initiation of antiretroviral therapy after HIV diagnosis[J]. AIDS Rev, 2019, 21(2): 55-64.
    [8]
    王爱华, 谢冬华, 刘智昱. 2016—2017年湖南省孕产妇艾滋病疫情特征及母婴阻断情况[J]. 中国艾滋病性病, 2018, 24(11): 1132-1134, 1142. https://www.cnki.com.cn/Article/CJFDTOTAL-XBYA201811016.htm
    [9]
    SHERMAN G G, MAZANDERANI A H, BARRON P, et al. Toward elimination of mother-to-child transmission of HIV in South Africa: how best to monitor early infant infections within the prevention of mother-to-child transmission program[J]. J Glob Health, 2017, 7(1): 010701. DOI: 10.7189/jogh.07.010701.
    [10]
    SELPH S S, BOUGATSOS C, DANA T, et al. Screening for HIV infection in pregnant women: updated evidence report and systematic review for the US preventive services task force[J]. JAMA, 2019, 321(23): 2349-2360. doi: 10.1001/jama.2019.2593
    [11]
    刘冬梅, 秦燕, 韦丹燕, 等. 不同孕周高效抗反转录病毒治疗对HIV母婴阻断效果的比较[J]. 中国临床新医学, 2016, 9(9): 770-772. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYLN201609005.htm
    [12]
    黄梅. 不同孕周进行抗病毒治疗对HIV感染母婴阻断的效果影响[J]. 世界最新医学信息文摘, 2016, 16(40): 60-61. https://www.cnki.com.cn/Article/CJFDTOTAL-WMIA201640044.htm
    [13]
    乔亚萍, 王潇滟, 王前, 等. 凉山彝族自治州2011—2016年HIV感染孕产妇抗病毒治疗及影响因素分析[J]. 中国艾滋病性病, 2019, 25(12): 1206-1210. https://www.cnki.com.cn/Article/CJFDTOTAL-XBYA201912002.htm
    [14]
    LE ROUX S M, ABRAMS E J, DONALD K A, et al. Infectious morbidity of breastfed, HIV-exposed uninfected infants under conditions of universal antiretroviral therapy in South Africa: a prospective cohort study[J]. Lancet Child Adolesc Health, 2020, 4(3): 220-231. http://www.sciencedirect.com/science/article/pii/S235246421930375X
    [15]
    MOSEHOLM E, HELLEBERG M, SANDHOLDT H, et al. Children exposed or unexposed to human immunodeficiency virus: weight, height, and body mass index during the first 5 years of life-a Danish nationwide cohort[J]. Clin Infect Dis, 2020, 70(10): 2168-2177. http://academic.oup.com/cid/article/70/10/2168/5528128
    [16]
    LANE C E, WIDEN E M, COLLINS S M, et al. HIV-exposed, uninfected infants in Uganda experience poorer growth and body composition trajectories than HIV-unexposed infants[J]. J Acquir Immune Defic Syndr, 2020, 85(2): 138-147. http://journals.lww.com/jaids/Abstract/2020/10010/HIV_Exposed,_Uninfected_Infants_in_Uganda.3.aspx
    [17]
    BOIVIN M J, MALIWICHI-SENGANIMALUNJE L, OGWANG L W, et al. Neurodevelopmental effects of ante-partum and post-partum antiretroviral exposure in HIV-exposed and uninfected children versus HIV-unexposed and uninfected children in Uganda and Malawi: a prospective cohort study[J]. Lancet HIV, 2019, 6(8): e518-e530. http://www.sciencedirect.com/science/article/pii/S2352301819300839
    [18]
    MSUKWA M T, KEISER O, JAHN A, et al. Timing of combination antiretroviral therapy (cART) initiation is not associated with stillbirth among HIV-infected pregnant women in Malawi[J]. Trop Med Int Health, 2019, 24(6): 727-735. http://www.ncbi.nlm.nih.gov/pubmed/30891866
    [19]
    TWABI H S, MANDA S O, SMALL D S. Assessing the effects of maternal HIV infection on pregnancy outcomes using cross-sectional data in Malawi[J]. BMC Public Health, 2020, 20(1): 974. http://www.researchgate.net/publication/340986288_Assessing_the_Effects_of_Maternal_HIV_Infection_on_Pregnancy_Outcomes_using_Cross-sectional_Data_in_Malawi
    [20]
    黄灿, 闫素英. 药物治疗管理服务对艾滋病患者用药依从性的影响[J]. 北京医学, 2020, 42(6): 523-526. https://www.cnki.com.cn/Article/CJFDTOTAL-BJYX202006012.htm
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(1)  / Tables(3)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (205) PDF downloads(3) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return