Volume 19 Issue 7
Jul.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(7): 1138-1141
LU Bao-xia, CHEN Rong-shou, WANG Shan, PENG Wan-sheng, ZHOU Rui. Clinical efficacy of fiberoptic bronchoscopy alveolar lavage in the treatment of Mycoplasma pneumoniae lobar pneumonia in children[J]. Chinese Journal of General Practice, 2021, 19(7): 1138-1141. doi: 10.16766/j.cnki.issn.1674-4152.002005
Citation: LU Bao-xia, CHEN Rong-shou, WANG Shan, PENG Wan-sheng, ZHOU Rui. Clinical efficacy of fiberoptic bronchoscopy alveolar lavage in the treatment of Mycoplasma pneumoniae lobar pneumonia in children[J]. Chinese Journal of General Practice, 2021, 19(7): 1138-1141. doi: 10.16766/j.cnki.issn.1674-4152.002005
shu

Clinical efficacy of fiberoptic bronchoscopy alveolar lavage in the treatment of Mycoplasma pneumoniae lobar pneumonia in children

doi: 10.16766/j.cnki.issn.1674-4152.002005
  • 1.

    Department of Pediatrics, Lu'an Hospital Affiliated to Anhui Medical University (Lu'an People's Hospital), Lu'an, Anhui 237005, China

Funds:

 KJ2019A0365

  • Received Date: 2020-10-21
    Available Online: 2022-02-16
    Abstract
  •   Objective  To observe the clinical curative effect, inflammatory index and immunity changes of Mycoplasma pneumoniae (MP) lobar pneumonia in children after treatment with fiberoptic bronchoscope alveolar lavage.  Methods  Total 60 children with lobar pneumonia caused by MP infection in the Department of Pediatrics of Lu'an people's Hospital from April 2019 to September 2020 were selected and randomly divided into observation group and control group with 30 cases in each group. The control group was given conventional treatment of Mycoplasma pneumoniae, and the observation group was given bronchoalveolar lavage under fiberoptic bronchoscope on the basis of conventional treatment. The clinical efficacy (including hospitalization time, cough disappearance time, body temperature recovery time), inflammatory factor levels, cellular immunity and humoral immunity indexes were compared between the two groups.  Results  (1) After treatment, the results of chest CT reexamination in the observation group showed that the lung shadow completely disappeared in 18 cases, partially disappeared in 10 cases, no change in 2 cases, the observation group was significantly better than the control group, the difference was statistically significant (P < 0.05). (2) In the observation group, cough disappearance time[(4.89±1.74) d], fever time[(2.63±0.56) d] and hospitalization days[(7.45±1.68) d] were less than those in the control group[(6.33±1.33) d, (3.85±1.29) d, (9.90±1.32) d, P < 0.05]. (3) Two sets of laboratory indexes after treatment, the levels of WBC, PCT, IL-6, TNF -α, CD3+, CD4+, CD4+/CD8+, IgA、IgM、IgG in the observation group were significantly better than those in the control group (all P < 0.05).  Conclusion  Bronchoalveolar lavage under fiberoptic bronchoscopy in the treatment of Mycoplasma pneumoniae lobar pneumonia can significantly improve the clinical efficacy, reduce inflammatory reaction, and accelerate the recovery of children's immunity.

     

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