Volume 19 Issue 9
Sep.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(9): 1514-1517,1556
GUO Mei, WANG Qi-wei, LIU Ding-li, WANG Lei. Application of non-invasive high-frequency oscillatory ventilation in infant respiratory distress syndrome[J]. Chinese Journal of General Practice, 2021, 19(9): 1514-1517,1556. doi: 10.16766/j.cnki.issn.1674-4152.002100
Citation: GUO Mei, WANG Qi-wei, LIU Ding-li, WANG Lei. Application of non-invasive high-frequency oscillatory ventilation in infant respiratory distress syndrome[J]. Chinese Journal of General Practice, 2021, 19(9): 1514-1517,1556. doi: 10.16766/j.cnki.issn.1674-4152.002100
shu

Application of non-invasive high-frequency oscillatory ventilation in infant respiratory distress syndrome

doi: 10.16766/j.cnki.issn.1674-4152.002100
  • 1.

    Department of Pediatrics, Women and Children Hospital of Fuyang, Fuyang, Anhui 236000, China

Funds:

 KJ2019A0342

  • Received Date: 2020-11-23
    Available Online: 2022-02-15
    Abstract
  •   Objective  To investigate the clinical effect of non-invasive high-frequency concussion ventilation and continuous positive airway pressure ventilation in the treatment of neonatal respiratory distress syndrome, whether it can reduce the incidence of complications and whether it can shorten the length of stay and reduce the number of hospitalisations.   Methods  A total of 74 cases of neonatal respiratory distress syndrome admitted in the NICU in our department from January 2018 to December 2019 were included. According to random number table method, the patients were divided into the non-invasive high-frequency group (NHFV group, 36 cases) and non-invasive positive pressure ventilation group (NCPAP group, 38 cases). The arterial blood oxygen levels, complications, duration of ventilator use and total length of hospital stay were compared before and after treatment at 12, 24, 48 and 72 h.   Results  PO2, A/APO2 and SaO2 in the NHFV group were higher than those in the NCPAP group at 12, 24, 48 and 72 h after respiratory support, and PaCO2 levels in the NHFV group at 12, 24, 48 and 72 h were lower than those in the NCPAP group, respectively (all P < 0.05). Both groups were treated and discharged, and no statistical significance was observed in the incidence of complications such as air leakage, persistent pulmonary hypertension, bronchopulmonary dysplasia, retinopathy, pulmonary haemorrhage, intracranial haemorrhage and other complications (all P>0.05). The duration of ventilator use and hospital stay in the NHFV group were shorter than those in the NCPAP group, and the difference was statistically significant (all P < 0.05).   Conclusion  Non-invasive high-frequency ventilation is an effective method for the treatment of neonatal respiratory distress syndrome. Compared with the traditional CPAP ventilation mode, it can significantly reduce CO2 retention, improve oxygenation index and shorten the length of hospital stay in children with respiratory distress syndrome, which is worthy of further clinical study.

     

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