Volume 19 Issue 10
Oct.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(10): 1629-1632
MA Han-bo, WU Si-yu, TONG Xiao-wen, LI Huai-fang. Comparative study of fractional CO2 laser and behavioural training in the treatment of overactive bladder in women[J]. Chinese Journal of General Practice, 2021, 19(10): 1629-1632. doi: 10.16766/j.cnki.issn.1674-4152.002128
Citation: MA Han-bo, WU Si-yu, TONG Xiao-wen, LI Huai-fang. Comparative study of fractional CO2 laser and behavioural training in the treatment of overactive bladder in women[J]. Chinese Journal of General Practice, 2021, 19(10): 1629-1632. doi: 10.16766/j.cnki.issn.1674-4152.002128
shu

Comparative study of fractional CO2 laser and behavioural training in the treatment of overactive bladder in women

doi: 10.16766/j.cnki.issn.1674-4152.002128

  • Department of Obstetrics and Gynecology, Tongji Hospital, Tongji University School of Medicine ，Shanghai 200065，China

Funds:

 81771560

 81873827

 82071630

  • Received Date: 2020-10-15
    Available Online: 2022-02-15
    Abstract
  •   Objective  To investigate the therapeutic effect and safety of fractional CO2 laser on overactive bladder (OAB) in women compared with behavioural training.  Methods  A total of 60 female OAB patients who visited the Department of Gynecology, Tongji Hospital from August 1, 2018 to January 30, 2020 were selected. They were randomly divided into the fractional CO2 laser group and behavioural training group, with 30 cases in each group, using a random number table. Follow-up was performed at 1 and 3 months after treatment. The overactive bladder symptom score (OABSS), urgency score, 24 h voiding frequency, pelvic organ prolapse/urinary incontinence sexual questionnaire (PISQ-12) and urodynamics were used to evaluate the therapeutic effect.  Results  Three months after treatment, the therapeutic effect of the fractional CO2 laser group was significantly better than that of the behavioural training group. The OABSS, urination symptom score and 24 h voiding frequency between the fractional CO2 laser group and behavioural training group were (1.87±0.81) points and (5.61±1.62) points, (1.04±0.27) points and (1.64±1.17) points, and (6.41±1.28) times and (10.07±3.21) times (all P < 0.05). The scores of the PISQ-12 questionnaire, including emotional factor and physiological factor, of the two groups were (47.75±5.16) points and (35.97±5.65) points, (21.68±2.43) points and (14.96±3.76) points, and (21.05±2.52) points and (15.45±4.43) points, and the difference was statistically significant (all P < 0.001). No significant difference was observed in partner factor (P>0.05). However, the PISQ-12 scores in the behavioural training group did not significantly differ before and after treatment. No adverse reactions such as aggravation of urinary tract symptoms occurred in both groups after treatment.  Conclusion  Compared with behavioural training, fractional CO2 laser has better efficacy and safety in the treatment of female OAB and can significantly improve the quality of sexual life of patients, which is worth promoting in clinical applications.

     

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