Volume 19 Issue 12
Dec.  2021
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(12): 1991-1994
WANG Wei-tao, ZHAO Jin-kang, MA Xing. Analysis of curative effect of 26 cases of pigmented villonodular synovitis of knee joint[J]. Chinese Journal of General Practice, 2021, 19(12): 1991-1994. doi: 10.16766/j.cnki.issn.1674-4152.002218
Citation: WANG Wei-tao, ZHAO Jin-kang, MA Xing. Analysis of curative effect of 26 cases of pigmented villonodular synovitis of knee joint[J]. Chinese Journal of General Practice, 2021, 19(12): 1991-1994. doi: 10.16766/j.cnki.issn.1674-4152.002218
shu

Analysis of curative effect of 26 cases of pigmented villonodular synovitis of knee joint

doi: 10.16766/j.cnki.issn.1674-4152.002218
  • 1.

    Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi 710000, China

Funds:

 2018YFC1106200

  • Received Date: 2020-09-04
    Available Online: 2022-03-02
    Abstract
  •   Objective  To analyze and compare the joint function and the improvement of joint pain in 26 patients with knee pigmented villonodular synovitis (PVNS) before and after arthroscopic synovectomy, evaluate the therapeutic value of arthroscopic treatment in patients with PVNS, and evaluate the effect of combined local treatment on the therapeutic effect of patients.  Methods  Twenty-six PVNS of the knee joint patients underwent arthroscopic synovectomy from January 2008 to December 2019 were analyzed retrospectively. Among them, 15 patients were treated with knee arthroscopy alone, and 11 patients were treated with local radiotherapy of diseased joints after operation. All 26 patients were followed up 88.6 (3-132) months. The joint pain score VAS score and knee function score Lysholm score were recorded before arthroscopic treatment and at the last follow-up, and the changes of VAS score and Lysholm score were statistically analyzed by t-test. The recurrence was determined by the joint swelling and pain and MRI evaluation results, and compared between the two groups.  Results  All 26 patients were followed up. The postoperative pathology showed that they were consistent with PVNS. The VAS score decreased from (4.60±0.88) points before surgery to (1.35±0.82) points at the last follow-up (P < 0.001), and Lysholm score increased from (41.00±7.45) points to (80.27±4.53) points (P < 0.001). The recurrence rate was 26.67% in the group receiving arthroscopy alone, and 9.09% in the group receiving arthroscopy combined with postoperative local radiotherapy (P>0.05).  Conclusion  Arthroscopy synoviectomy can relieve the pain and improve the joint function of the PVNS, and postoperative combined with local radiotherapy has a better therapeutic effect.

     

    • FullText(HTML)
  • loading
    • References(18)
  • [1]
    BERNTHAL N M, ISHMAEL C R, BURKE Z D C. Management of pigmented villonodular synovitis (PVNS): An orthopedic surgeon's perspective[J]. Current Oncology Reports, 2020, 22(6): 63-68. doi: 10.1007/s11912-020-00926-7
    [2]
    李瑞, 李鸿斌, 薛文贵, 等. 33例色素沉着绒毛结节性滑膜炎回顾性分析[J]. 内蒙古医科大学学报, 2020, 42(2): 193-196, 213. https://www.cnki.com.cn/Article/CJFDTOTAL-NMYX202002021.htm
    [3]
    DAMODAR D, CHAN N, KOKOT N. Pigmented villonodular synovitis of the temporomandibular joint: Case report and review of the literature[J]. Head Neck, 2015, 37(12): 194-199. doi: 10.1002/hed.24056
    [4]
    STEPHAN S R, SHALLOP B, LACKMAN R, et al. Pigmented villonodular synovitis: A comprehensive review and proposed treatment algorithm[J]. JBJS Rev, 2016, 4(7): e3.
    [5]
    VACA M, POLO R, MARTINEZ-SAN-MILLAN J, et al. Pigmented villonodular synovitis of the temporomandibular joint with petrous bone invasion[J]. Otol Neurotol, 2017, 38(5): 58-59. doi: 10.1097/MAO.0000000000001390
    [6]
    丁振禹, 何耀华. 色素沉着绒毛结节性滑膜炎诊治进展[J]. 国际骨科学杂志, 2017, 38(2): 79-82. doi: 10.3969/j.issn.1673-7083.2017.02.004
    [7]
    GOUIN F, NOAILLES T. Localized and diffuse forms of tenosynovial giant cell tumor (formerly giant cell tumbor of the tendon sheath and pigmented villonodular synovitis)[J]. Orthop Traumatol Surg Res, 2017, 103(1S): S91-S97.
    [8]
    FALEK A, NIEMUNIS-SAWICKA J, WRONA K, et al. Pigmented villonodular synovitis[J]. Folia Med Cracov, 2018, 58(4): 93-104.
    [9]
    COSSEDDU F, SHYTAJ S, SACCHETTI F, et al. Malignant pigmented villonodular synovitis: A brief literature review and case report[J]. Clin Cases Miner Bone Metab, 2020, 16(2): 181-185. http://www.researchgate.net/publication/338735804_Malignant_pigmented_villonodular_synovitis_a_brief_literature_review_and_case_report
    [10]
    AL FARII H, ZHOU S, TURCOTTE R. The surgical outcome and recurrence rate of tenosynovial giant cell tumor in the elbow: A literature review[J]. Shoulder Elbow Surg, 2019, 28(9): 1835-1840. doi: 10.1016/j.jse.2019.05.007
    [11]
    任翠, 朱巧, 郎宁, 等. 膝关节弥漫性滑膜病变的MRI诊断及鉴别诊断[J]. 实用放射学杂志, 2020, 36(4): 615-619. doi: 10.3969/j.issn.1002-1671.2020.04.027
    [12]
    TRITSCHLER P, BAUDREZ V, MUTIJIMA E. Diffuse pigmented villonodular synovitis of the subtalar joint[J]. J Belg Soc Radiol, 2018, 102: 11-12.
    [13]
    MASTBOOM M J L, V ERSPOOR F G M, V ERSCHOOR A J, et al. Higher incidence rates than previously known in tenosynovial giant cell tumors[J]. Acta Orthop, 2017, 88(6): 688-694. doi: 10.1080/17453674.2017.1361126
    [14]
    CHANG J S, HIGGINS J P, KOSY J D, et al. Systematic arthroscopic treatment of diffuse pigmented villonodular synovitis in the knee[J]. Arthrosc Tech, 2017, 6(5): e1547-e1551. doi: 10.1016/j.eats.2017.06.029
    [15]
    康真. 色素沉着绒毛结节性滑膜炎术后放疗的临床观察[J]. 影像研究与医学应用, 2020, 4(22): 208-209. doi: 10.3969/j.issn.2096-3807.2020.22.109
    [16]
    AVCI G G. The Importance and side effects of radiotherapy for diffuse pigmented villonodular synovitis; Case reports and literature review[J]. Acta Oncologica Turcica, 2020, 53(1): 162-165. doi: 10.5505/aot.2020.42744
    [17]
    BENNER B, GOOD L, QUIROGA D, et al. Pexidartinib, a novel small molecule csf-1r inhibitor in use for tenosynovial giant cell tumor: A systematic review of pre-clinical and clinical development[J]. Drug Des Devel Ther, 2020, 14: 1693-1704. doi: 10.2147/DDDT.S253232
    [18]
    STAALS E L, FERRARI S, DONATI D M, et al. Diffuse-type tenosynovial giant cell tumour: Current treatment concepts and future perspectives[J]. Eur J Cancer, 2016, 63: 34-40. http://www.researchgate.net/profile/Emanuela_Palmerini/publication/303815275_Diffuse-type_tenosynovial_giant_cell_tumour_Current_treatment_concepts_and_future_perspectives/links/575d2d4508aec91374ad2b15.pdf
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(2)  / Tables(1)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (228) PDF downloads(23) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return