Volume 19 Issue 12
Dec.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(12): 2035-2037,2087
ZHANG Tie-lin, LI Rui, WU Shu-mei. Relationship between glycosylated haemoglobin and prognosis of patients with acute pontine infarction[J]. Chinese Journal of General Practice, 2021, 19(12): 2035-2037,2087. doi: 10.16766/j.cnki.issn.1674-4152.002229
Citation: ZHANG Tie-lin, LI Rui, WU Shu-mei. Relationship between glycosylated haemoglobin and prognosis of patients with acute pontine infarction[J]. Chinese Journal of General Practice, 2021, 19(12): 2035-2037,2087. doi: 10.16766/j.cnki.issn.1674-4152.002229
shu

Relationship between glycosylated haemoglobin and prognosis of patients with acute pontine infarction

doi: 10.16766/j.cnki.issn.1674-4152.002229
  • 1.

    Department of Neurology, the Eighth People's Hospital of Hefei, Hefei, Anhui 230011, China

Funds:

 82001452

  • Received Date: 2021-04-13
    Available Online: 2022-03-02
    Abstract
  •   Objective  To investigate the relationship between glycosylated haemoglobin (HbA1c) and prognosis of patients with acute pontine infarction.  Methods  The relationship between the history of diabetes, fasting blood glucose and HbA1c after admission, and the scores of modified Rankin score (mRS) and daily life self-care ability (ADL) at 90 d follow-up in 85 patients with acute pontine infarction in Hefei Eighth People's Hospital from May 2016 to April -2018 were analysed.  Results  A significant correlation between HbA1c and prognosis (mRS < 3) was observed in patients with pontine infarction at 90-day follow-up (OR=0.234, 95% CI: 0.073-0.784, P=0.014). In addition, no significant correlation amongst HbA1c ≥ 6.1% (OR=0.404, 95% CI: 0.138-1.188, P=0.100), history of diabetes (OR=0.556, 95% CI: 0.197-1.565, P=0.266), fasting blood glucose ≥ 7.0 mmol/L (OR=0.516, 95% CI: 0.179-1.488, P=0.221) and ADL>60 was observed in patients at 90-day follow-up. HbA1c had higher AUC value (mRS < 3, AUC=0.725, 95% CI: 0.615-0.835, P=0.001; ADL>60, AUC=0.682, 95% CI: 0.556-0.808, P=0.016) than diabetes history and fasting blood glucose.  Conclusion  Compared with fasting blood glucose and diabetes history, glycosylated haemoglobin may have an advantage in evaluating the prognosis of patients with acute pontine infarction.

     

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