Volume 19 Issue 12
Dec.  2021
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(12): 2149-2152
NIU Fang, YANG Xi, SHEN Xiao-ying, GU Yu-yan, XIE Shu-ping, XIE Ling-nv. Clinical characteristics and nursing management of SCLC patients complicated with hyponatremia during radiotherapy and chemotherapy[J]. Chinese Journal of General Practice, 2021, 19(12): 2149-2152. doi: 10.16766/j.cnki.issn.1674-4152.002258
Citation: NIU Fang, YANG Xi, SHEN Xiao-ying, GU Yu-yan, XIE Shu-ping, XIE Ling-nv. Clinical characteristics and nursing management of SCLC patients complicated with hyponatremia during radiotherapy and chemotherapy[J]. Chinese Journal of General Practice, 2021, 19(12): 2149-2152. doi: 10.16766/j.cnki.issn.1674-4152.002258
shu

Clinical characteristics and nursing management of SCLC patients complicated with hyponatremia during radiotherapy and chemotherapy

doi: 10.16766/j.cnki.issn.1674-4152.002258
  • 1.

    Department of Thoracic Radiotherapy, Cancer Hospital of University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, Zhejiang 310022, China

Funds:

 2018ZB023

 QN201805

  • Received Date: 2020-05-23
    Abstract
  •   Objective  To analyze the clinical characteristics of hyponatremia in patients with small cell lung cancer (SCLC) during radiotherapy and chemotherapy, explore nursing management strategies, and provide reference for clinical practice.  Methods  A total of 87 patients with SCLC admitted in our hospital from September 2017 to December 2019 were selected as the research object. The general clinical data of patients and the serum sodium values of different treatment stages were collected retrospectively. The clinical characteristics of SCLC complicated with hyponatremia were analyzed. The strategies for nursing management was explored.  Results  Eighty-seven cases of SCLC patients complicated with hyponatremia in 35 cases (40.23%). The incidence of hyponatremia at the initial treatment, after 2 courses of chemotherapy, at the beginning and end of radiotherapy, and after the last treatment were 6.90%, 5.96%, 13.16%, 15.19% and 23.52%, respectively. The incidences of mild, moderate and severe hyponatremia were 46.99%, 11.48% and 6.26%, respectively, and the total incidence of hyponatremia was 64.73%. The clinical manifestations of 35 SCLC patients with hyponatremia were 15 cases of anorexia (42.86%), 9 cases of nausea/vomiting (25.71%), 6 cases of dizziness (17.14%), 20 cases of fatigue (57.14%), 2 cases of abnormal mental behavior (5.71%), and 7 cases of hidden symptoms (20.00%).  Conclusion  The incidence of concurrent hyponatremia in SCLC patients during radiotherapy and chemotherapy is high, and can occur in different treatment stages, and the clinical manifestations are in many forms. In the SCLC peri-chemotherapy period, attention should be paid to the observation and care of hyponatremia.

     

    • FullText(HTML)
  • loading
    • References(21)
  • [1]
    刘诗昂. 58例小细胞肺癌合并低钠血症的临床特点及预后分析[D]. 大连: 大连医科大学, 2018.
    [2]
    孔月, 徐裕金, 唐华容, 等. 低钠血症与SCLC患者预后关系研究[J]. 中华放射肿瘤学杂志, 2016, 25(2): 126-130. doi: 10.3760/cma.j.issn.1004-4221.2016.02.009
    [3]
    朱晶, 马丽霞, 王胜, 等. 小细胞肺癌并发低钠血症的临床特点并12例临床分析[J]. 吉林医学, 2011, 32(25): 5311-5312. doi: 10.3969/j.issn.1004-0412.2011.25.083
    [4]
    黄燕, 邹长虹, 张荣成, 等. 住院心力衰竭患者入院时低钠血症的发生率及其对预后的影响[J]. 中华心血管病杂志, 2015, 43(10): 868-873. doi: 10.3760/cma.j.issn.0253-3758.2015.10.007
    [5]
    卜巧云, 亓民. 老年人心力衰竭合并低钠血症72例临床分析[J]. 中国基层医药, 2016, 23(11): 1680-1682. doi: 10.3760/cma.j.issn.1008-6706.2016.11.020
    [6]
    BERARDI R, RINALDI S, CARAMANTI M, et al. Hyponatremia in cancer patients: Time for a new approach[J]. Crit Rev Oncol/Hematol, 2016, 102: 15-25. doi: 10.1016/j.critrevonc.2016.03.010
    [7]
    张宇, 李新, 张红梅, 等. 老年骨质疏松及伴有低钠血症骨质疏松患者的临床研究[J]. 中华老年医学杂志, 2017, 36(8): 872-876. doi: 10.3760/cma.j.issn.0254-9026.2017.08.010
    [8]
    GROHE C, BERARDI R, BURST V. Hyponatraemia-SIADH in lung cancer diagnostic and treatment algorithms[J]. Crit Rev Oncol/Hematol, 2015, 96(1): 1-8. doi: 10.1016/j.critrevonc.2015.04.005
    [9]
    SPASOVSKI G, VANHOLDER R, ALLOLIO B, et al. Clinical practice guideline on diagnosis and treatment of hyponatraemia[J]. Intensive Care Med, 2014, 40(3): 320-331. doi: 10.1007/s00134-014-3210-2
    [10]
    曹伟新, 李乐之. 外科护理学[M]. 北京: 人民卫生出版社, 2010: 9-10.
    [11]
    马芳, 刘先领, 胡春宏, 等. 小细胞肺癌合并低钠血症的临床特点及预后分析[J]. 中南大学学报(医学版), 2011, 36(1): 64-67. doi: 10.3969/j.issn.1672-7347.2011.01.010
    [12]
    李哗雄. 肿瘤放射治疗学[M]. 北京: 中国协和医科大学出版社, 2018: 716.
    [13]
    王利琴, 谢淑萍, 沈佳琴, 等. 肺癌患者55例放疗同步化疗期间营养状况分析[J]. 中国基层医药, 2016, 23(22): 3373-3377. doi: 10.3760/cma.j.issn.1008-6706.2016.22.004
    [14]
    伍军伟, 凌俊宏, 谭欣, 等. 低钠血症诊治的相关研究进展分析[J]. 中国继续医学教育, 2018, 10(26): 97-98. doi: 10.3969/j.issn.1674-9308.2018.26.045
    [15]
    董祥宁, 蒋宗惠, 秦涛, 等. 晚期肿瘤合并低钠低钾的诊疗[J]. 中华全科医学, 2011, 9(2): 201-202. https://www.cnki.com.cn/Article/CJFDTOTAL-SYQY201102020.htm
    [16]
    刘巍, 朱惠娟, 张化冰, 等. 低钠血症1例报告及诊断路径分析[J]. 北京医学, 2016, 38(4): 322-324. https://www.cnki.com.cn/Article/CJFDTOTAL-BJYX201604013.htm
    [17]
    张佐涛, 李悟斌, 张育芬, 等. 肺癌患者低钠血症补钠致精神异常1例[J]. 神经疾病与精神卫生, 2016, 16(2): 247-248. doi: 10.3969/j.issn.1009-6574.2016.02.036
    [18]
    陶维玲. 颅脑损伤重度低钠血症患者不同速度静脉补钠效果的观察[J]. 当代护士(中旬刊), 2015(7): 45-46. https://www.cnki.com.cn/Article/CJFDTOTAL-DDHS201507027.htm
    [19]
    蒋月强, 李瑞超. 托伐普坦治疗小细胞肺癌伴抗利尿激素异常分泌综合征所致的低钠血症[J]. 中国医院药学杂志, 2017, 37(22): 2281-2284. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGYZ201722016.htm
    [20]
    刘学啸, 朱虹, 杜德希, 等. 放射治疗对肺癌患者免疫功能的影响[J]. 中华全科医学, 2017, 15(6): 1062-1064. https://www.cnki.com.cn/Article/CJFDTOTAL-SYQY201706046.htm
    [21]
    章敏, 谢淑萍, 杨希, 等. 肺癌放疗前患者心理痛苦状况及相关因素分析[J]. 中华全科医学, 2018, 16(3): 488-491. https://www.cnki.com.cn/Article/CJFDTOTAL-SYQY201803046.htm
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(2)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (203) PDF downloads(4) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return