Volume 20 Issue 1
Jan.  2022
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LI Yan-li, GAO Qing-yun, FENG Jun-bo, ZHANG Cheng-xin, GE Sheng-lin. The death risk factors of Stanford A aortic dissection surgery[J]. Chinese Journal of General Practice, 2022, 20(1): 18-21, 103. doi: 10.16766/j.cnki.issn.1674-4152.002266
Citation: LI Yan-li, GAO Qing-yun, FENG Jun-bo, ZHANG Cheng-xin, GE Sheng-lin. The death risk factors of Stanford A aortic dissection surgery[J]. Chinese Journal of General Practice, 2022, 20(1): 18-21, 103. doi: 10.16766/j.cnki.issn.1674-4152.002266

The death risk factors of Stanford A aortic dissection surgery

doi: 10.16766/j.cnki.issn.1674-4152.002266
Funds:

 1808085MH279

  • Received Date: 2020-05-16
    Available Online: 2022-03-03
  •   Objective  To explore the death risk factors after Stanford A aortic dissection surgery based on the perioperative data of patients with Stanford A aortic dissection.  Methods  A total of 68 patients with Stanford A aortic dissection from January 2012 to January 2020 were enrolled in the Cardiovascular Surgery Department of the First Affiliated Hospital of AnHui Medical University for the retrospective analysis. Based on clinical outcome, patients were divided into survival group (n=50) and death group (n=18). The preoperative, intraoperative and postoperative clinical data was summarized and studied retrospectively. Univariate analysis was performed by t2 test and further, multivariate analysis was performed by logistic regression based on significant results from univariate analysis to identify the death risk factors after Stanford A aortic dissection surgery.  Results  There were significant differences between two groups by univariate analysis for preoperative LVEF < 50%, preoperative hypotension, preoperative pericardial effusion, preoperative neurological disorder, involved coronary arteries, involved aortic valve, intraoperative lactic acid, ultrafiltration, urine volume and supportive cardiopulmonary by pass running time (all P < 0.05). Subsequently, preoperative LVEF < 50% (OR=33.163, P=0.037) and supportive cardiopulmonary bypass running time (OR=1.248, P=0.004) were significant factors by logistic regression analysis. Postoperatively, there were significant differences for extubation time, reoperation, re-intubation, awaking time, CRRT, postoperative lactic acid and ICU stay (all P < 0.05).  Conclusion  Both preoperative LVEF < 50% and supportive cardiopulmonary bypass running time are the death risk factors of Stanford A aortic dissection surgery.

     

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