Volume 20 Issue 1
Jan.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(1): 165-168
ZHOU Cong-cong, LIN Chu-jun, HONG Jing. Study on the preventive value of infection prevention and control system for perioperative nosocomial infection in patients with traumatic fracture[J]. Chinese Journal of General Practice, 2022, 20(1): 165-168. doi: 10.16766/j.cnki.issn.1674-4152.002303
Citation: ZHOU Cong-cong, LIN Chu-jun, HONG Jing. Study on the preventive value of infection prevention and control system for perioperative nosocomial infection in patients with traumatic fracture[J]. Chinese Journal of General Practice, 2022, 20(1): 165-168. doi: 10.16766/j.cnki.issn.1674-4152.002303
shu

Study on the preventive value of infection prevention and control system for perioperative nosocomial infection in patients with traumatic fracture

doi: 10.16766/j.cnki.issn.1674-4152.002303

  • Department of Orthopedics, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China

Funds:

 Y202044407

  • Received Date: 2021-01-08
    Available Online: 2022-03-03
    Abstract
  •   Objective  Infection is a common complication of traumatic fracture, which can be life-threatening in severe cases. It is necessary to effectively prevent nosocomial infection in patients with traumatic fracture. By discussing the value of constructing infection prevention and control system, we can provide guidance for clinical prevention of nosocomial infection.  Methods  Total 88 patients with traumatic fracture collected in our hospital from July 2019 to September 2020 were randomly divided into control group (routine intervention) and observation group (construction of infection prevention and control system). The nosocomial infection rate, inflammatory factor index, fracture healing and complication rate of the two groups were compared.  Results  The incidence of nosocomial infection in the observation group (2.27%) was significantly lower than that in the control group (18.18%), the difference was statistically significant (P < 0.05). Before intervention, there was no significant difference in the level of CRP, IL-1β and TNF-α in the two groups (all P>0.05). After intervention, the levels of CRP [(7.89±1.40) mg/L], IL-1β [(20.08±3.11) pg/mL] and TNF-α [(7.89±1.20) pg/mL] in the observation group were lower than those in the control group [(11.01±1.42) mg/L, (25.11±3.34) pg/mL, (12.01±1.40) pg/mL, all P < 0.05]. The clinical healing rate (93.18%) and fracture healing rate (100.00%) in the observation group were higher than those in the control group (77.27% and 81.82%, all P < 0.05). The incidence of complications in the observation group (4.55%) was lower than that in the control group (20.45%, P < 0.05).  Conclusion  The construction and application of infection prevention and control system has a significant effect, which can effectively reduce the incidence of postoperative complications of traumatic fracture and improve inflammatory indexes and fracture healing.

     

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