Volume 20 Issue 2
Feb.  2022
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(2): 294-297
FAN Xiao-hua, CHEN Cun-guo, GUAN Jian-min, LU Wen-ming, ZOU Tao. Value of contrast-enhanced ultrasound in evaluating the efficacy of digital subtraction angiography-guided hepatic artery chemoembolisation in patients with hepatocellular carcinoma[J]. Chinese Journal of General Practice, 2022, 20(2): 294-297. doi: 10.16766/j.cnki.issn.1674-4152.002336
Citation: FAN Xiao-hua, CHEN Cun-guo, GUAN Jian-min, LU Wen-ming, ZOU Tao. Value of contrast-enhanced ultrasound in evaluating the efficacy of digital subtraction angiography-guided hepatic artery chemoembolisation in patients with hepatocellular carcinoma[J]. Chinese Journal of General Practice, 2022, 20(2): 294-297. doi: 10.16766/j.cnki.issn.1674-4152.002336
shu

Value of contrast-enhanced ultrasound in evaluating the efficacy of digital subtraction angiography-guided hepatic artery chemoembolisation in patients with hepatocellular carcinoma

doi: 10.16766/j.cnki.issn.1674-4152.002336
  • 1.

    Department of Ultrasound, the First People's Hospital of Huzhou, Huzhou, Zhejiang 313000, China

Funds:

 LGF19H180001

  • Received Date: 2021-06-08
    Available Online: 2022-03-04
    Abstract
  •   Objective  To investigate the role of contrast-enhanced ultrasound in evaluating the efficacy of digital subtraction angiography (DSA) -guided hepatic artery chemoembolisation (TACE) in patients with hepatocellular carcinoma (HCC).  Methods  A total of 68 patients with HCC who were admitted to Huzhou First People's Hospital and Taizhou Hospital of Zhejiang Province from January 2020 to April 2021 were selected as study participants. All patients underwent DSA-guided TACE treatment, and contrast-enhanced ultrasound was used to evaluate the efficacy before and after treatment.  Results  (1) The initial increase time, peak time and peak acceleration time significantly increased after treatment (t=11.701, 10.383, 10.119, all P < 0.05), whereas the initial growth rate and the enhancement rate significantly reduced (t=9.636, 11.318, all P < 0.05). (2) The initial increase time, peak time and peak acceleration time were significantly longer after than before treatment (P < 0.05) in the effective group (t=7.867, 12.407, 16.127, all P < 0.05). The initial increase rate and enhancement rate were significantly lower after than before treatment (t=12.134, 23.613, all P < 0.05). (3) The initial increase time, peak time, peak acceleration time, initial increase speed and enhancement rate AUC were 0.657, 0.718, 0.642, 0.669 and 0.714, respectively.  Conclusion  The peak time and enhancement rate in contrast-enhanced ultrasound have high value in predicting the therapeutic effect of TACE in patients with HCC.

     

    • FullText(HTML)
  • loading
    • References(17)
  • [1]
    ZOU J, LI C, CHEN Y, et al. Retrospective analysis of transcatheter arterial chemoembolization treatment for spontaneously ruptured hepatocellular carcinoma[J]. Oncol Lett, 2019, 18(6): 6423-6430. http://www.ncbi.nlm.nih.gov/pubmed/31807165
    [2]
    SHIMOSE S, TANAKA M, IWAMOTO H, et al. Prognostic impact of transcatheter arterial chemoembolization (TACE) combined with radiofrequency ablation in patients with unresectable hepatocellular carcinoma: Comparison with TACE alone using decision-tree analysis after propensity score matching[J]. Hepatol Res, 2019, 49(8): 919-928. doi: 10.1111/hepr.13348
    [3]
    柳昂, 许伟, 徐浩, 等. 三维-数字减影血管造影技术在肝动脉化学治疗栓塞术中的应用价值探讨[J]. 中华肝脏病杂志, 2018, 26(6): 436-440. doi: 10.3760/cma.j.issn.1007-3418.2018.06.009
    [4]
    HIRAOKA A, KUMADA T, MICHIAKA K, et al. Newly proposed ALBI grade and ALBI-T score as tools for assessment of hepatic function and prognosis in hepatocellular carcinoma patients[J]. Liver Cancer, 2019, 8(5): 312-325. doi: 10.1159/000494844
    [5]
    曾俊, 谭利华, 伍玉枝, 等. TACE结合立体定向体部X-刀治疗肝癌的临床疗效研究[J]. 现代生物医学进展, 2018, 18 (13): 2469-2472, 2521. https://www.cnki.com.cn/Article/CJFDTOTAL-SWCX201813014.htm
    [6]
    DIETRICH C F, TEUFEL A, SIRLIN C B, et al. Surveillance of hepatocellular carcinoma by medical imaging[J]. Quant Imaging Med Surg, 2019, 9(11): 1904-1910. doi: 10.21037/qims.2019.10.04
    [7]
    张小晶, 王琳. 微血管侵犯在肝癌综合诊断与治疗中的临床意义[J]. 中华消化外科杂志, 2019, 18(4): 336-341. doi: 10.3760/cma.j.issn.1673-9752.2019.04.008
    [8]
    SONG S K, PARK M G, PARK S K, et al. MicroRNAs associated with microvascular invasion in hepatocellular carcinoma and their prognostic impacts in patients undergoing hepatic resection[J]. Oncol Lett, 2019, 18(6): 6293-6303. http://www.ncbi.nlm.nih.gov/pubmed/31788107
    [9]
    张少平. MRI对原发性肝癌介入术的疗效评估[J]. 中国医学影像学杂志, 2019, 27(5): 397-400. doi: 10.3969/j.issn.1005-5185.2019.05.019
    [10]
    XU X, ZHANG H L, LIU Q P, et al. Radiomic analysis of contrast-enhanced CT predicts microvascular invasion and outcome in hepatocellular carcinoma[J]. J Hepatol, 2019, 70(6): 1133-1144. doi: 10.1016/j.jhep.2019.02.023
    [11]
    赖全图, 李果, 周琴, 等. 超声造影对肝癌肝移植术后复发肿瘤的诊断价值[J]. 实用癌症杂志, 2018, 33(7): 1216-1218. doi: 10.3969/j.issn.1001-5930.2018.07.051
    [12]
    刘春堂, 陈勇良, 李若旭, 等. 复发性微小肝癌超声造影与磁共振增强扫描及DWI表现分析[J]. 中国医疗设备, 2019, 34(3): 78-81. doi: 10.3969/j.issn.1674-1633.2019.03.022
    [13]
    SCHAIBLE J, STROSZCZYNSKI C, BEYER L P, et al. Quantitative perfusion analysis of hepatocellular carcinoma using dynamic contrast enhanced ultrasound (CEUS) to determine tumor micro vascularization[J]. Clin Hemorheol Microcirc, 2019, 73(1): 95-104. doi: 10.3233/CH-199221
    [14]
    ZHOU G, CAI Z Q, LUO J, et al. Prognostic value of enhancement rate by enhanced ultrasound in hepatitis B virus-positive hepatocellular carcinoma undergoing radiofrequency ablation[J]. Asia Pac J Clin Oncol, 2019, 15(4): 238-243. http://www.ncbi.nlm.nih.gov/pubmed/31119840
    [15]
    XIA C Q, XIANG Z, XUE B L, et al. Predictive value of contrast-enhanced ultrasound for early recurrence of single lesion hepatocellular carcinoma after curative resection[J]. Ultrason Imaging, 2019, 41(1): 49-58. doi: 10.1177/0161734618815231
    [16]
    袁月德, 刘梅存. 三维彩色多普勒超声与超声造影对鉴别诊断原发性肝癌及转移性肝癌的价值[J]. 中国医疗设备, 2018, 33(6): 78-81. doi: 10.3969/j.issn.1674-1633.2018.06.020
    [17]
    刘杰, 邱广平, 涂朝勇, 等. 经动脉导管介入治疗中晚期肝癌患者的近期疗效分析[J]. 中华全科医学, 2017, 15(9): 1509-1511, 1538. https://www.cnki.com.cn/Article/CJFDTOTAL-SYQY201709019.htm
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(1)  / Tables(3)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (619) PDF downloads(2) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return