Volume 20 Issue 2
Feb.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(2): 294-297
FAN Xiao-hua, CHEN Cun-guo, GUAN Jian-min, LU Wen-ming, ZOU Tao. Value of contrast-enhanced ultrasound in evaluating the efficacy of digital subtraction angiography-guided hepatic artery chemoembolisation in patients with hepatocellular carcinoma[J]. Chinese Journal of General Practice, 2022, 20(2): 294-297. doi: 10.16766/j.cnki.issn.1674-4152.002336
Citation: FAN Xiao-hua, CHEN Cun-guo, GUAN Jian-min, LU Wen-ming, ZOU Tao. Value of contrast-enhanced ultrasound in evaluating the efficacy of digital subtraction angiography-guided hepatic artery chemoembolisation in patients with hepatocellular carcinoma[J]. Chinese Journal of General Practice, 2022, 20(2): 294-297. doi: 10.16766/j.cnki.issn.1674-4152.002336
shu

Value of contrast-enhanced ultrasound in evaluating the efficacy of digital subtraction angiography-guided hepatic artery chemoembolisation in patients with hepatocellular carcinoma

doi: 10.16766/j.cnki.issn.1674-4152.002336
  • 1.

    Department of Ultrasound, the First People's Hospital of Huzhou, Huzhou, Zhejiang 313000, China

Funds:

 LGF19H180001

  • Received Date: 2021-06-08
    Available Online: 2022-03-04
    Abstract
  •   Objective  To investigate the role of contrast-enhanced ultrasound in evaluating the efficacy of digital subtraction angiography (DSA) -guided hepatic artery chemoembolisation (TACE) in patients with hepatocellular carcinoma (HCC).  Methods  A total of 68 patients with HCC who were admitted to Huzhou First People's Hospital and Taizhou Hospital of Zhejiang Province from January 2020 to April 2021 were selected as study participants. All patients underwent DSA-guided TACE treatment, and contrast-enhanced ultrasound was used to evaluate the efficacy before and after treatment.  Results  (1) The initial increase time, peak time and peak acceleration time significantly increased after treatment (t=11.701, 10.383, 10.119, all P < 0.05), whereas the initial growth rate and the enhancement rate significantly reduced (t=9.636, 11.318, all P < 0.05). (2) The initial increase time, peak time and peak acceleration time were significantly longer after than before treatment (P < 0.05) in the effective group (t=7.867, 12.407, 16.127, all P < 0.05). The initial increase rate and enhancement rate were significantly lower after than before treatment (t=12.134, 23.613, all P < 0.05). (3) The initial increase time, peak time, peak acceleration time, initial increase speed and enhancement rate AUC were 0.657, 0.718, 0.642, 0.669 and 0.714, respectively.  Conclusion  The peak time and enhancement rate in contrast-enhanced ultrasound have high value in predicting the therapeutic effect of TACE in patients with HCC.

     

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