Volume 20 Issue 4
Apr.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(4): 602-605
ZHENG Li-hua, YANG Shu-fen, LAN Yun-ping, XU Chen-zhan, WU Xiao-min. Effect of anesthesia induction with esmketamine combined with cisatracurium in emergency cesarean section[J]. Chinese Journal of General Practice, 2022, 20(4): 602-605. doi: 10.16766/j.cnki.issn.1674-4152.002410
Citation: ZHENG Li-hua, YANG Shu-fen, LAN Yun-ping, XU Chen-zhan, WU Xiao-min. Effect of anesthesia induction with esmketamine combined with cisatracurium in emergency cesarean section[J]. Chinese Journal of General Practice, 2022, 20(4): 602-605. doi: 10.16766/j.cnki.issn.1674-4152.002410
shu

Effect of anesthesia induction with esmketamine combined with cisatracurium in emergency cesarean section

doi: 10.16766/j.cnki.issn.1674-4152.002410
  • 1.

    Department of Anesthesiology, Quzhou People ' s Hospital, Quzhou Hospital Affiliated to Wenzhou Medical University, Quzhou, Zhejiang 324000, China

Funds:

 2021KY461

 2020-29

  • Received Date: 2021-12-14
    Available Online: 2022-08-20
    Abstract
  •   Objective  To observe the effect of anesthesia induction with esmketamine combined with cisatracurium in emergency cesarean section, and to explore a safe and effective anesthesia method to provide reference for clinical practice.  Methods  A total of 120 emergency cesarean section parturients treated in Quzhou People ' s Hospital from January 2020 to December 2020 were randomly divided into control group and observation group. 60 cases in the control group were induced by remifentanil combined with cisatracurium anesthesia, and 60 cases in the observation group were induced by esmketamine combined with cisatracurium anesthesia. The Vital signs of the mother, postpartum pain score, neonatal condition, depression score and adverse reactions were compared between the two groups.  Results  There were significant differences in heart rate and mean arterial pressure between the two groups (all P < 0.05). The heart rate and mean arterial pressure at skin cutting and fetal removal in the two groups were higher than those before anesthesia (all P < 0.05). The heart rate at the end of operation in the observation group was lower than that in the control group (P < 0.05), and the average arterial pressure at the time of skin cutting, fetal removal and the end of operation were lower than those in the control group (all P < 0.05). There was significant difference in pain scores between the two groups (all P < 0.05). The pain scores at 6, 12, 24 and 48 hours postpartum in the two groups were higher than those at 2 hours postpartum (all P < 0.05). The pain scores of the observation group at 2, 6, 12, 24 and 48 hours postpartum were lower than those of the control group (all P < 0.05). The umbilical cord blood pH and Apgar score of newborns in the observation group were higher than those in the control group (all P < 0.05). The score of Edinburgh Postpartum Depression Scale in the observation group at 6 weeks postpartum was lower than that in the control group [(7.62±3.29) points vs. (10.07±4.63) points, P < 0.05]. The incidence of adverse reactions in the observation group (3.33%) was lower than that in the control group (13.33%, P < 0.05).  Conclusion  The application effect of anesthesia induction of esmketamine combined with cisatracurium in emergency cesarean section is good. It can stabilize maternal vital signs, reduce postpartum pain and depression, improve the situation of newborns, and has less adverse reactions.

     

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