Research progress of the influencing factors and interventions of psychosocial distress in hematopoietic stem cell transplant patients

ZHANG Ting; HAN Ai-zhi; GE Jian; LONG Zhang-biao

doi:10.16766/j.cnki.issn.1674-4152.002422

Volume 20 Issue 4

Apr. 2022

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Article Navigation > Chinese Journal of General Practice > 2022 > 20(4): 651-654

ZHANG Ting, HAN Ai-zhi, GE Jian, LONG Zhang-biao. Research progress of the influencing factors and interventions of psychosocial distress in hematopoietic stem cell transplant patients[J]. Chinese Journal of General Practice, 2022, 20(4): 651-654. doi: 10.16766/j.cnki.issn.1674-4152.002422

Citation:

ZHANG Ting, HAN Ai-zhi, GE Jian, LONG Zhang-biao. Research progress of the influencing factors and interventions of psychosocial distress in hematopoietic stem cell transplant patients[J]. Chinese Journal of General Practice, 2022, 20(4): 651-654. doi: 10.16766/j.cnki.issn.1674-4152.002422

Citation:

ZHANG Ting, HAN Ai-zhi, GE Jian, LONG Zhang-biao. Research progress of the influencing factors and interventions of psychosocial distress in hematopoietic stem cell transplant patients[J]. Chinese Journal of General Practice, 2022, 20(4): 651-654. doi: 10.16766/j.cnki.issn.1674-4152.002422

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Research progress of the influencing factors and interventions of psychosocial distress in hematopoietic stem cell transplant patients

doi: 10.16766/j.cnki.issn.1674-4152.002422

Department of Hematology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230032, China

Funds:

81900118

1708085MH224

201904a07020057

Received Date: 2021-10-27
Available Online: 2022-08-20

Abstract

Abstract

Psychological distress is an unpleasant emotional experience caused by multiple factors. These experiences can affect patients' ability to effectively cope with cancer and its physical symptoms and treatment, significantly reduce their quality of life and affect health outcomes. Psychological distress is the most common psychological problem in hematopoietic stem cell transplant (HSCT) patients, which is listed as the sixth vital sign by the International Oncology Society. It is often manifested as anxiety and depression, post-traumatic stress disorder, sleep disorder, delirium, fatigue and other uncomfortable symptoms. At present, a large number of studies have been conducted on the influencing factors and intervention methods of HSCT patients' psychological distress. These studies suggest that female, age, pain, physical function, negative coping and low family social function are the influencing factors of psychological distress in HSCT patients. At the same time, the intervention methods of HSCT patients' psychological distress were reported, including psychobehavioural therapy, exercise therapy, music therapy, health education intervention and palliative care. These intervention methods have been proved to reduce patients' bad mood, improve psychological state, reduce the level of psychological distress and improve the quality of life of patients. This series of studies provides the basis and theoretical guidance for the implementation of nursing interventions for HSCT patients. At the same time, a multi-centre, large-sample longitudinal study should be conducted in China in the future to further clarify the influencing factors and mechanism of HSCT patients' psychological distress and explore a practical, safe and feasible intervention program. This paper reviews the above content through literature review.
- Hematopoietic stem cell transplant,
- Psychosocial distress,
- Influencing factors,
- Nursing interventions

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References(46)

References

[1]	NAKAMURA Z M, NASH R P, QUILLEN L J, et al. Psychiatric care in hematopoietic stem cell transplantation[J]. Psychosomatics, 2019, 60(3): 227-237. doi: 10.1016/j.psym.2019.01.005
[2]	黄晓军. 实用造血干细胞移植[M]. 2版. 北京: 人民卫生出版社, 2019: 423-433. HUANG X J. Practical hematopoietic stem cell transplantation[M]. 2nd Ed. Beijing: People's Medical Publishing House, 2013: 423-433.
[3]	WOLFF D, HERZBERG P Y, HERRMANN A, et al. Post-transplant multimorbidity index and quality of life in patients with chronic graft-versus-host disease-results from a joint evaluation of a prospective German multicenter validation trial and a cohort from the National Institutes of Health[J]. Bone Marrow Transplant, 2021, 56(1): 243-256. doi: 10.1038/s41409-020-01017-8
[4]	JANICSÁK H, UNGVARI G S, GAZDAG G. Psychosocial aspects of hematopoietic stem cell transplantation[J]. World J Transplant, 2021, 11(7): 263-276. doi: 10.5500/wjt.v11.i7.263
[5]	温小珊, 张桂华. 造血干细胞移植患者净化舱内心理困扰的影响因素[J]. 护理实践与研究, 2021, 18(9): 1286-1289. doi: 10.3969/j.issn.1672-9676.2021.09.006 WEN X S, ZHANG G H. Influencing factors of the psychological disturbance of hematopoietic stem cell transplantation patients in the purified cabin[J]. Nursing Practice and Research, 2021, 18(9): 1286-1289. doi: 10.3969/j.issn.1672-9676.2021.09.006
[6]	FITCH M I, ASHBURY F, NICOLL I. Reflections on the implementation of screening for distress (sixth vital sign) in Canada: Key lessons learned[J]. Support Care Cancer, 2018, 26(12): 4011-4020. doi: 10.1007/s00520-018-4278-y
[7]	AMONOO H L, MASSEY C N, FREEDMAN M E, et al. Psychological considerations in hematopoietic stem cell transplantation[J]. Psychosomatics, 2019, 60(4): 331-342. doi: 10.1016/j.psym.2019.02.004
[8]	张璟, 刘东玲, 王坤. 甲状腺癌病人心理困扰影响因素的研究进展[J]. 护理研究, 2018, 32(17): 2684-2687. doi: 10.12102/j.issn.1009-6493.2018.17.012 ZHANG J, LIU D L, WANG K. Research progress on influencing factors of psychological distress in thyroid cancer patients[J]. Chinese Nursing Research, 2018, 32(17): 2684-2687. doi: 10.12102/j.issn.1009-6493.2018.17.012
[9]	GUNDELACH A, HENRY B. Cancer-related psychological distress: A concept analysis[J]. Clin J Oncol Nurs, 2016, 20(6): 630-634. doi: 10.1188/16.CJON.630-634
[10]	RIBA M B, DONOVAN K A, ANDERSEN B, et al. Distress management, Version 3.2019, NCCN clinical practice guidelines in oncology[J]. J Natl Compr Canc Netw, 2019, 17(10): 1229-1249. doi: 10.6004/jnccn.2019.0048
[11]	郭彩玲, 张川莉, 陈凤姣, 等. 造血干细胞移植患者的心理情绪及躯体症状分析[J]. 国际输血及血液学杂志, 2020, 43(2): 134-141. doi: 10.3760/cma.j.cn511693-20190927-00153 GUO C L, ZHANG C L, CHEN F J, et al. Analysis of psychological emotion and phyiscal symptoms in patients undergoing hematopoietic stem cell transplantation[J]. International Journal of Blood Transfusion and Hematology, 2020, 43(2): 134-141. doi: 10.3760/cma.j.cn511693-20190927-00153
[12]	CARRILLO-VALDEZ L, MARÍA L, GUTIÉRREZ-ESCAMILLA, et al. Psychological evaluation in Hematopoietic Stem Cell Transplantation[J]. J Basic App Psychol Res, 2020, 2(3): 1-6. doi: 10.29057/jbapr.v2i3.4720
[13]	SEO H J, BAEK Y G, CHO B S, et al. Anxiety and depression of the patients with hematological malignancies during hospitalization for hematopoietic stem cell transplantation[J]. Psychiatry Investig, 2019, 16(10): 751-758. doi: 10.30773/pi.2019.07.12
[14]	ESSER P, KUBA K, SCHERWATH A, et al. Posttraumatic stress disorder symptomatology in the course of allogeneic HSCT: A prospective study[J]. J Cancer Surviv, 2017, 11(2): 203-210. doi: 10.1007/s11764-016-0579-7
[15]	RENTSCHER K E, CARROLL J E, JUCKETT M B, et al. Sleep disruption, fatigue, and depression as predictors of 6-year clinical outcomes following allogeneic hematopoietic cell transplantation[J]. J Natl Cancer Inst, 2021, 113(10): 1405-1414. doi: 10.1093/jnci/djab032
[16]	BUBALO J. Managing the mental distress of the hematopoietic stem cell transplant (HSCT) patient: A focus on delirium[J]. Curr Hematol Malig Rep, 2018, 13(2): 109-113. doi: 10.1007/s11899-018-0441-2
[17]	刘欢, 李成媛, 黄辉, 等. 造血干细胞移植术后患者疲乏、心理弹性与抑郁的相关性[J]. 解放军护理杂志, 2020, 37(11): 47-50, 58. doi: 10.3969/j.issn.1008-9993.2020.11.012 LIU H, CHEN C Y, HUANG H, et al. Relationship among fatigue, psychological elasticity and depression in hematopoietic stem cell transplant patients[J]. Nursing Journal of Chinese People's Liberation Army, 2020, 37(11): 47-50, 58. doi: 10.3969/j.issn.1008-9993.2020.11.012
[18]	EL-JAWAHRI A, TRAEGER L, GREER J A, et al. Effect of inpatient palliative care during hematopoietic stem-cell transplant on psychological distress 6 months after transplant: Results of a randomized clinical trial[J]. J Clin Oncol, 2017, 35(32): 3714-3721. doi: 10.1200/JCO.2017.73.2800
[19]	BRAAMSE A M J, YI J C, VISSER O J, et al. Developing a Risk prediction model for long-term physical and psychological functioning after hematopoietic cell transplantion[J]. Biol Blood Marrow Transplant, 2016, 22(3): 549-556. doi: 10.1016/j.bbmt.2015.11.1102
[20]	JIM H S L, SUTTON S K, SMALL B J, et al. Trajectories of quality of life after hematopoietic cell transplantation: Secondary analysis of blood and marrow transplant clinical trials network 0902 data[J]. Biol Blood Marrow Transplant, 2016, 22(11): 2077-2083. doi: 10.1016/j.bbmt.2016.08.012
[21]	方云, 张小蓉, 刘敏杰, 等. 造血干细胞移植患者认知功能状况及影响因素分析[J]. 护理学杂志, 2021, 36(9): 26-29. doi: 10.3870/j.issn.1001-4152.2021.09.026 FANG Y, ZHANG X R, LIU M J, et al. Cognitive function and its influencing factors among patients undergoing hematopoietic stem cell transplantation[J]. Journal of Nursing Science, 2021, 36(9): 26-29. doi: 10.3870/j.issn.1001-4152.2021.09.026
[22]	匡大林, 丁萍, 韩江英, 等. 癌症患者的心理困扰及其影响因素分析[J]. 安徽医学, 2019, 40(8): 939-942. doi: 10.3969/j.issn.1000-0399.2019.08.028 KUANG D L, DING P, HAN J Y, et al. Analysis of psychological distress and its influencing factors in cancer patients[J]. Anhui Medical Journal, 2019, 40(8): 939-942. doi: 10.3969/j.issn.1000-0399.2019.08.028
[23]	KÖHLER N, MEHNERT A, GÖTZE H. Psychological distress, chronic conditions and quality of life in elderly hematologic cancer patients: Study protocol of a prospective study[J]. BMC Cancer, 2017, 17(1): 700-708. doi: 10.1186/s12885-017-3662-1
[24]	BALIOUSIS M, RENNOLDSON M, DAWSON D L, et al. Perceptions of hematopoietic stem cell transplantation and coping predict emotional distress during the acute phase after transplantation[J]. Oncol Nurs Forum, 2017, 44(1): 96-107. doi: 10.1188/17.ONF.96-107
[25]	EL-JAWAHRI A R, VANDUSEN H B, TRAEGER L N, et al. Quality of life and mood predict posttraumatic stress disorder after hematopoietic stem cell transplantation[J]. Cancer, 2016, 122(5): 806-812. doi: 10.1002/cncr.29818
[26]	EHRLICH K B, MILLER G E, SCHEIDE T, et al. Pre-transplant emotional support is associated with longer survival after allogeneic hematopoietic stem cell transplantation[J]. Bone Marrow Transplant, 2016, 51(12): 1594-1598. doi: 10.1038/bmt.2016.191
[27]	AMONOO H L, JOHNSON P C, DHAWALE T M, et al. Sharing and caring: The impact of social support on quality of life and health outcomes in hematopoietic stem cell transplantation[J]. Cancer, 2021, 127(8): 1260-1265. doi: 10.1002/cncr.33455
[28]	YU H, LI L, LIU C, et al. Factors associated with the quality of life of family caregivers for leukemia patients in China[J]. Health Qual Life Outcomes, 2017, 15(1): 55-65. doi: 10.1186/s12955-017-0628-6
[29]	RUEDA-LARA M, LOPEZ-PATTON M R. Psychiatric and psychosocial challenges in patients undergoing haematopoietic stem cell transplants[J]. Int Rev Psychiatry, 2014, 26(1): 74-86. doi: 10.3109/09540261.2013.866075
[30]	WALSH C A, YI J C, ROSENBERG A R, et al. Factors associated with social functioning among long-term cancer survivors treated with hematopoietic stem cell transplantation as adolescents or young adults[J]. Psychooncology, 2020, 29(10): 1579-1586. doi: 10.1002/pon.5460
[31]	POSLUSZNY D M, BOVBJERG D H, SYRJALA K L, et al. Correlates of anxiety and depression symptoms among patients and their family caregivers prior to allogeneic hematopoietic cell transplant for hematological malignancies[J]. Support Care Cancer, 2019, 27(2): 591-600. doi: 10.1007/s00520-018-4346-3
[32]	EL-JAWAHRI A, CHEN Y B, BRAZAUSKAS R, et al. Impact of pre-transplant depression on outcomes of allogeneic and autologous hematopoietic stem cell transplantation[J]. Cancer, 2017, 123(10): 1828-1838. doi: 10.1002/cncr.30546
[33]	AMONOO H L, KURUKULASURIYA C, CHILSON K, et al. Improving quality of life in hematopoietic stem cell transplantation survivors through a positive psychology intervention[J]. Biol Blood Marrow Transplant, 2020, 26(6): 1144-1153. doi: 10.1016/j.bbmt.2020.02.013
[34]	PENALBA V, ASVAT Y, DESHIELDS T L, et al. Rates and predictors of psychotherapy utilization after psychosocial evaluation for stem cell transplant[J]. Psychooncology, 2018, 27(2): 427-433. doi: 10.1002/pon.4473
[35]	李媛, 叶红芳, 张新月. 运动干预对造血干细胞移植患者生命质量影响的meta分析[J]. 临床与病理杂志, 2018, 38(1): 138-146. https://www.cnki.com.cn/Article/CJFDTOTAL-WYSB201801024.htm LI Y, YE H F, ZHANG X Y. Physical exercise for quality of life of patients undergoing hematopoietic stem cell transplantation: A meta-analysis[J]. Journal of Clinical and Pathological Research, 2018, 38(1): 138-146. https://www.cnki.com.cn/Article/CJFDTOTAL-WYSB201801024.htm
[36]	SANTA-MINA D, DOLAN L B, LIPTON J H, et al. Exercise before, during, and after hospitalization for allogeneic hematological stem cell transplant: A feasibility randomized controlled trial[J]. J Clin Med, 2020, 9(6): 1854-1868. doi: 10.3390/jcm9061854
[37]	MORISHITA S, KAIDA K, YAMAUCHI S, et al. Relationship of physical activity with physical function and health-related quality of life in patients having undergone allogneic haematopoietic stem-cell transplantation[J]. Eur J Cancer Care, 2017, 26(4). DOI: 10.1111/ecc.12669.
[38]	HACKER E D, COLLINS E, PARK C, et al. Strength training to enhance early recovery after hematopoietic stem cell transplantation[J]. Biol Blood Marrow Transplant, 2017, 23(4): 659-669. doi: 10.1016/j.bbmt.2016.12.637
[39]	DÓRO C A, NETO J Z, CUNHA R, et al. Music therapy improves the mood of patients undergoing hematopoietic stem cells transplantation(controlled randomized study)[J]. Support Care Cancer, 2017, 25(3): 1013-1018. doi: 10.1007/s00520-016-3529-z
[40]	GEYIK GÏ, DOĜAN S, OZBEK H, et al. The effect of music therapy on the physical and mental parameters of cancer patients during hematopoietic stem cell transplantation[J]. Perspect Psychiatr Care, 2021, 57(2): 558-564. doi: 10.1111/ppc.12578
[41]	厉雪琴, 王黎红, 邵文斐, 等. 饮食干预管理和健康教育对糖尿病酮症酸中毒患者健康情况的影响[J]. 中华全科医学, 2019, 17(2): 262-264. doi: 10.16766/j.cnki.issn.1674-4152.000656 LI X Q, WANG L H, SHAO W P, et al. Clinical effect of dietary nursing interventions and health education in diabetes mellitus patients with ketoacidosis[J]. Chinese Journal of General Practice, 2019, 17(2): 262-264. doi: 10.16766/j.cnki.issn.1674-4152.000656
[42]	CIOCE M, LOHMEYER F M, MORONI R, et al. Impact of Educational interventions on psychological distress during allogeneic hematopoietic stem cell transplantation: A randomised study[J]. Mediterr J Hematol Infect Dis, 2020, 12(1): e2020067. DOI: 10.4084/MJHID.2020.067.
[43]	PHILIP J, LE-GAUTIER R, COLLINS A, et al. Care plus study: A multi-site implementation of early palliative care in routine practice to improve health outcomes and reduce hospital admissions for people with advanced cancer: A study protocol[J]. BMC Health Serv Res, 2021, 21(1): 513-522. doi: 10.1186/s12913-021-06476-3
[44]	LOGGERS E T, LEBLANC T W, EL-JAWAHRI A, et al. Pretransplantation supportive and palliative care consultation for high-risk hematopoietic cell transplantation patients[J]. Biol Blood Marrow Transplant, 2016, 22(7): 1299-1305. doi: 10.1016/j.bbmt.2016.03.006
[45]	EL-JAWAHRI A, LEBLANC T, VANDUSEN H, et al. Effect of inpatient palliative care on quality of life 2 weeks after hematopoietic stem cell transplantation: A randomized clinical trial[J]. JAMA, 2016, 316(20): 2094-2103. doi: 10.1001/jama.2016.16786
[46]	吴小林, 龚红霞, 赵旭, 等. 多维度姑息护理对终末期血液肿瘤患者营养、心理状况和生活质量的影响[J]. 现代肿瘤医学, 2020, 28(22): 3973-3977. doi: 10.3969/j.issn.1672-4992.2020.22.030 WU X L, GONG H X, ZHAO X, et al. Effects of multi-dimension palliative care on nutritional, psychological status and life of quality among patients with end-stage hematoma[J]. Journal of Modern Oncology, 2020, 28(22): 3973-3977. doi: 10.3969/j.issn.1672-4992.2020.22.030

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Research progress of the influencing factors and interventions of psychosocial distress in hematopoietic stem cell transplant patients

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Research progress of the influencing factors and interventions of psychosocial distress in hematopoietic stem cell transplant patients

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