Volume 20 Issue 4
Apr.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(4): 678-680
ZHANG Shu-hong, LING Ying-Chun, SHENG Gao-yang. Effects of rehabilitation treatment at different time points on neurological function in elderly patients with cerebral infarction[J]. Chinese Journal of General Practice, 2022, 20(4): 678-680. doi: 10.16766/j.cnki.issn.1674-4152.002428
Citation: ZHANG Shu-hong, LING Ying-Chun, SHENG Gao-yang. Effects of rehabilitation treatment at different time points on neurological function in elderly patients with cerebral infarction[J]. Chinese Journal of General Practice, 2022, 20(4): 678-680. doi: 10.16766/j.cnki.issn.1674-4152.002428
shu

Effects of rehabilitation treatment at different time points on neurological function in elderly patients with cerebral infarction

doi: 10.16766/j.cnki.issn.1674-4152.002428
  • 1.

    Department of Neurology, Longyou People's Hospital, Quzhou, Zhejiang 324400, China

Funds:

 2022KY1309

  • Received Date: 2021-12-03
    Available Online: 2022-08-20
    Abstract
  •   Objective  To explore the effect of rehabilitation treatment at different time points on elderly patients with cerebral infarction and its impact on neurological function, so as to provide reference basis for the formulation of clinical rehabilitation treatment plan.  Methods  A total of 180 elderly patients with cerebral infarction treated in the Department of Neurology of Longyou People's Hospital from May 2018 to May 2021 were randomly divided into the observation group and control group, with 90 cases in each group. The two groups received rehabilitation treatment for 4 weeks within 2 weeks and 2-4 weeks after the patient's vital signs were stable. The National Institutes of Health stroke scale (NIHSS) score, Fugl-Meyer assessment (FMA) score, Barthel Index (BI) score, levels of inflammatory factors (interleukin-6, tumour necrosis factor-α, high-sensitivity C-reactive protein) and rehabilitation effect were observed in the two groups.  Results  The NIHSS score of the two groups decreased significantly after treatment (P < 0.05), with the observation group having a significantly lower score than the control group [(7.61±1.87) points vs. (8.95±2.09) points, P < 0.05]. After treatment, the FMA score of the two groups increased significantly (P < 0.05), with the observation group having a significantly higher score than the control group [(73.06±6.34) points vs. (64.15±4.78) points, P < 0.05]. The BI scores of the two groups increased significantly after treatment (P < 0.05), with the observation group having a significantly higher score than the control group [(68.35±6.83) points vs. (57.11±7.29) points, P < 0.05]. The levels of interleukin-6, tumour necrosis factor-α and high-sensitivity C-reactive protein of the two groups increased significantly after treatment (P < 0.05), and the observation group had lower levels compared with the control group (P < 0.05). The total effective rate of the observation group was 84.44%, which was significantly higher than that in the control group (71.11%, P < 0.05).  Conclusion  Rehabilitation treatment for elderly patients with cerebral infarction within 2 weeks after the stability of vital signs can improve neurological function, limb function and activities of daily living, reduce the level of inflammatory factors, and improve the rehabilitation effect.

     

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    • References(21)
  • [1]
    戴胜兵, 严旺, 刘艳, 等. 尤瑞克林治疗急性脑梗死患者的疗效和安全性评价[J]. 中华全科医学, 2019, 17(6): 1046-1048. doi: 10.16766/j.cnki.issn.1674-4152.000858

    DAI S B, YAN W, LIU Y, et al. Efficacy and safety evaluation of urecolin in the treatment of patients with acute cerebral infarction[J]. Chin Gen Med, 2019, 17(6): 1046-1048. doi: 10.16766/j.cnki.issn.1674-4152.000858
    [2]
    林东如, 叶志方, 黄婉洁. 早期神经康复对急性脑梗死静脉溶栓患者神经功能和日常生活能力的影响[J]. 白求恩医学杂志, 2020, 18(3): 256-257. https://www.cnki.com.cn/Article/CJFDTOTAL-BQEN202003024.htm

    LIN D R, YE Z F, HUANG W J. Effects of early neurological rehabilitation on neurological function and activities of daily living in patients with acute cerebral infarction undergoing intravenous thrombolysis[J]. Beth J Med, 2020, 18(3): 50-51. https://www.cnki.com.cn/Article/CJFDTOTAL-BQEN202003024.htm
    [3]
    张振军, 李应平, 陈武泽, 等. 动作观察疗法康复治疗结合功能磁共振成像在脑梗死病人中应用效果: 一项随机、对照、开放单中心临床研究[J]. 安徽医药, 2019, 23(12): 2407-2410. doi: 10.3969/j.issn.1009-6469.2019.12.019

    ZHANG Z J, LI Y P, CHEN W Z, et al. Effect of action observation therapy rehabilitation therapy combined with functional magnetic resonance imaging in patients with cerebral infarction: a randomized, controlled, open single center clinical study[J]. AnHui Med, 2019, 23(12): 2407-2410. doi: 10.3969/j.issn.1009-6469.2019.12.019
    [4]
    鲍晓, 刘惠宇, 罗津宁, 等. 间歇性低氧训练联合常规康复治疗对脑梗死患者认知和运动功能的影响[J]. 中华航海医学与高气压医学杂志, 2019, 26(3): 232, 234, 259. doi: 10.3760/cma.j.issn.1009-6906.2019.03.016

    BAO X, LIU H Y, LUO J N, et al. Effect of intermittent hypoxia training combined with routine rehabilitation on cognitive and motor function in patients with cerebral infarction[J]. Chin J Naut Med & Hyp Med, 2019, 26(3): 232-234, 259. doi: 10.3760/cma.j.issn.1009-6906.2019.03.016
    [5]
    马灿灿, 张熙斌, 徐耀, 等. 急性脑梗死患者静脉溶栓联合超早期神经康复的疗效观察[J]. 中华老年心脑血管病杂志, 2018, 20(10): 1049-1053. doi: 10.3969/j.issn.1009-0126.2018.10.011

    MA C C, ZHANG X B, XU Y, et al. Effect of intravenous thrombolysis combined with ultra early neurological rehabilitation in patients with acute cerebral infarction[J]. Chin J Ger Cardiov & Cerebrov Dis, 2018, 20(10): 1049-1053. doi: 10.3969/j.issn.1009-0126.2018.10.011
    [6]
    刘江波. 急性脑梗死患者早期康复治疗不同介入时机的临床比较[J]. 中西医结合心血管病电子杂志, 2018, 6(10): 76, 78. https://www.cnki.com.cn/Article/CJFDTOTAL-ZXJH201810056.htm

    LIU J B. Clinical comparison of early rehabilitation treatment in patients with acute cerebral infarction at different intervention times[J]. Cardiov Dis Integr Trad Chin & West Med, 2018, 6 (10): 84, 86. https://www.cnki.com.cn/Article/CJFDTOTAL-ZXJH201810056.htm
    [7]
    莫海东. 脑梗死瘫痪患者不同时机康复介入治疗效果对比观察[J]. 医学理论与实践, 2019, 32(7): 984-986. https://www.cnki.com.cn/Article/CJFDTOTAL-YXLL201907023.htm

    MO H D. Comparative observation on the effect of different time machine rehabilitation interventional therapy in patients with cerebral infarction paralysis[J]. Med Theory & Pract, 2019, 32(7): 54-56. https://www.cnki.com.cn/Article/CJFDTOTAL-YXLL201907023.htm
    [8]
    中华医学会神经病学分会脑血管病学组急性缺血性脑卒中诊治指南撰写组. 中国急性缺血性脑卒中诊治指南2010[J]. 中国临床医生, 2011, 39(3): 67-73. https://www.cnki.com.cn/Article/CJFDTOTAL-XDJB201911024.htm

    Chinese Medical Association Nneurology Branch Cerebrovascular Disease Group Acute Ischemic Stroke Diagnosis and Treatment Guide Writing Group. Chinese guidelines for diagnosis and treatment of acute ischemic stroke 2010[J]. Chin Clinic, 2011, 2(3): 50-59. https://www.cnki.com.cn/Article/CJFDTOTAL-XDJB201911024.htm
    [9]
    郑立敏, 赵琳, 王亚杰, 等. 常规康复治疗联合有氧训练对老年急性脑梗死患者神经功能的影响[J]. 广西医科大学学报, 2018, 35(5): 679-682. https://www.cnki.com.cn/Article/CJFDTOTAL-GXYD201805024.htm

    ZHENG L M, ZHAO L, WANG Y J, et al. Effect of routine rehabilitation therapy combined with aerobic training on neurological function in elderly patients with acute cerebral infarction[J]. J GuangXi Med Univers, 2018, 35(5): 679-682. https://www.cnki.com.cn/Article/CJFDTOTAL-GXYD201805024.htm
    [10]
    王顺达, 刘振国, 杨俊生, 等. 早期综合康复对脑梗死偏瘫患者上肢功能及临床疗效的影响研究[J]. 国际老年医学杂志, 2017, 38(6): 278-281. doi: 10.3969/j.issn.1674-7593.2017.06.010

    WANG S D, LIU Z G, YANG J S, et al. Effect of early comprehensive rehabilitation on upper limb function and clinical efficacy of patients with cerebral infarction and hemiplegia[J]. Internat J Geriatr, 2017, 38(6): 278-281. doi: 10.3969/j.issn.1674-7593.2017.06.010
    [11]
    侯义红. 奥扎格雷钠、血塞通结合早期康复训练对脑梗死患者NIHSS评分、下肢运动功能及日常生活能力的影响[J]. 现代诊断与治疗, 2021, 32(6): 967-968. https://www.cnki.com.cn/Article/CJFDTOTAL-XDZD202106062.htm

    HOU Y H. Effects of ozagrel sodium and Xuesaitong combined with early rehabilitation training on NIHSS score, lower limb motor function and activities of daily living in patients with cerebral infarction[J]. Mod Diagn & Treatm, 2021, 32(6): 967-968. https://www.cnki.com.cn/Article/CJFDTOTAL-XDZD202106062.htm
    [12]
    李莉霞, 黄燕, 陈梅, 等. 重复经颅磁刺激联合康复训练治疗不同亚型脑梗死患者的临床效果研究[J]. 心肺血管病杂志, 2018, 37(5): 415-419. doi: 10.3969/j.issn.1007-5062.2018.05.009

    LI L X, HUANG Y, CHEN M, et al. Clinical effect of repeated transcranial magnetic stimulation combined with rehabilitation training on patients with different subtypes of cerebral infarction[J]. J Cardiopulm Vasc Dis, 2018, 37(5): 415-419. doi: 10.3969/j.issn.1007-5062.2018.05.009
    [13]
    黄信群, 周霞. 规范三级康复治疗联合依达拉奉对脑梗死患者神经营养状态、氧化应激损伤的影响[J]. 海南医学院学报, 2017, 23(24): 3452-3455. https://www.cnki.com.cn/Article/CJFDTOTAL-HNYY201724033.htm

    HUANG X Q, ZHOU X. To standardize the effect of three-level rehabilitation therapy combined with edaravone on neurotrophic status and oxidative stress injury in patients with cerebral infarction[J]. J HaiNan Med Coll, 2017, 23(24): 3452-3455. https://www.cnki.com.cn/Article/CJFDTOTAL-HNYY201724033.htm
    [14]
    张伟平, 屈洪党, 许力. 丁苯酞注射液对脑梗死患者血清细胞凋亡因子水平的影响[J]. 中华全科医学, 2019, 17(7): 1087-1089, 1190. doi: 10.16766/j.cnki.issn.1674-4152.000869

    ZHANG W P, QU H D, XU L. Effect of butylphthalide injection on the level of serum apoptotic factors in patients with cerebral infarction[J]. Chin Gen Pract, 2019, 17(7): 1087-1089, 1190. doi: 10.16766/j.cnki.issn.1674-4152.000869
    [15]
    曲芝平. 综合性康复训练联合常规药物对脑梗死患者血浆同型半胱氨酸水平和神经功能缺损的影响[J]. 中国药物与临床, 2019, 19(4): 639-641. https://www.cnki.com.cn/Article/CJFDTOTAL-YWLC201904055.htm

    QU Z P. Effects of comprehensive rehabilitation training combined with conventional drugs on plasma homocysteine level and neurological deficit in patients with cerebral infarction[J]. Chin J Med & Clin, 2019, 19(4): 639-641. https://www.cnki.com.cn/Article/CJFDTOTAL-YWLC201904055.htm
    [16]
    周述娜, 王蕾, 仇莹莹, 等. 早期康复对脑梗死患者运动功能和日常生活活动能力的影响[J]. 中国临床保健杂志, 2019, 22(6): 759-762. doi: 10.3969/J.issn.1672-6790.2019.06.010

    ZHOU S N, WANG L, QIU Y Y, et al. Effects of early rehabilitation on motor function and activities of daily living in patients with cerebral infarction[J]. Chin J Clin Health Care, 2019, 22(6): 759-762. doi: 10.3969/J.issn.1672-6790.2019.06.010
    [17]
    王昌权. 早期康复训练对急性脑梗死患者运动功能及血清脑源性神经营养因子水平的影响[J]. 新乡医学院学报, 2017, 34(10): 946-948, 955. https://www.cnki.com.cn/Article/CJFDTOTAL-XXYX201710022.htm

    WANG C Q. Effect of early rehabilitation training on motor function and serum brain-derived neurotrophic factor level in patients with acute cerebral infarction[J]. J XinXiang Med Coll, 2017, 34(10): 946-948. https://www.cnki.com.cn/Article/CJFDTOTAL-XXYX201710022.htm
    [18]
    梁权, 樊启财, 陈双杰. 早期康复训练对急性脑梗死偏瘫患者运动功能和PCs、SDF-1α水平的影响[J]. 河北医药, 2017, 39(5): 720-722. https://www.cnki.com.cn/Article/CJFDTOTAL-HBYZ201705022.htm

    LIANG Q, FAN Q C, CHEN S J. Effects of early rehabilitation training on motor function, PCs and SDF-1 in patients with acute cerebral infarction and hemiplegia α Horizontal influence[J]. HeBei Med, 2017, 39(5): 720-722. https://www.cnki.com.cn/Article/CJFDTOTAL-HBYZ201705022.htm
    [19]
    崔振平. 早期康复训练对急性脑梗死患者血清NGF、NSE、BDNF及运动功能的影响[J]. 海南医学院学报, 2017, 23(5): 593-595, 599. https://www.cnki.com.cn/Article/CJFDTOTAL-HNYY201705005.htm

    CUI Z P. Effects of early rehabilitation training on serum NGF, NSE, BDNF and motor function in patients with acute cerebral infarction[J]. J HaiNan Med Coll, 2017, 23(5): 593-595, 599. https://www.cnki.com.cn/Article/CJFDTOTAL-HNYY201705005.htm
    [20]
    刘芬. 不同康复训练介入时间对脑梗死患者肢体功能恢复的影响[J]. 双足与保健, 2017, 26(2): 24-25. https://www.cnki.com.cn/Article/CJFDTOTAL-SZBJ201702013.htm

    LIU F. Effects of different rehabilitation training intervention time on limb function recovery in patients with cerebral infarction[J]. Bip & Health Care, 2017, 26(2): 24-25. https://www.cnki.com.cn/Article/CJFDTOTAL-SZBJ201702013.htm
    [21]
    许济, 李花, 田苗, 等. 不同时机康复训练对老年脑梗死患者的影响[J]. 中国临床医生杂志, 2020, 48(4): 427-429. doi: 10.3969/j.issn.2095-8552.2020.04.015

    XU J, LI H, TIAN M, et al. Effects of different timing rehabilitation training on elderly patients with cerebral infarction[J]. Chin J Clinic, 2020, 48(4): 427-429. doi: 10.3969/j.issn.2095-8552.2020.04.015
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