Application value of bicycle exercise therapy and gabapentin in the treatment of haemodialysis patients with restless legs syndrome

XIA Min; CHEN Fu-xing

doi:10.16766/j.cnki.issn.1674-4152.002456

Volume 20 Issue 5

May 2022

Turn off MathJax

Article Contents

Article Navigation > Chinese Journal of General Practice > 2022 > 20(5): 793-795

XIA Min, CHEN Fu-xing. Application value of bicycle exercise therapy and gabapentin in the treatment of haemodialysis patients with restless legs syndrome[J]. Chinese Journal of General Practice, 2022, 20(5): 793-795. doi: 10.16766/j.cnki.issn.1674-4152.002456

Citation:

XIA Min, CHEN Fu-xing. Application value of bicycle exercise therapy and gabapentin in the treatment of haemodialysis patients with restless legs syndrome[J]. Chinese Journal of General Practice, 2022, 20(5): 793-795. doi: 10.16766/j.cnki.issn.1674-4152.002456

Citation:

PDF( 404 KB)

Application value of bicycle exercise therapy and gabapentin in the treatment of haemodialysis patients with restless legs syndrome

doi: 10.16766/j.cnki.issn.1674-4152.002456

XIA Min¹
, CHEN Fu-xing^{2
,
,}

1.
Department of Nephrology, People's Hospital of Beilun District, Ningbo, Zhejiang 330206, China

Funds:

2019KY654

Received Date: 2021-01-06
Available Online: 2022-09-05

Abstract

Abstract

Objective To analyse the effects of cycling exercise therapy and gabapentin in the treatment of haemodialysis patients with restless legs syndrome (RLS), and determine their effects on sleep quality and quality of life. Methods Sixty haemodialysis patients with RLS admitted in People's Hospital of Beilun District from December 2018 to June 2020 were randomly divided into the observation group and control group. The control group was treated with gabapentin, and the observation group was treated with bicycle exercise therapy and gabapentin. The clinical efficacy, sleep quality and quality of life were investigated before and after 12 weeks of treatment. Results After treatment, the IRLS scale score, AIS scale score and PSQI scale score of the observation group were significantly lower than those of the control group [(7.03±1.83) points vs. (13.64±2.11) points, (4.12±1.11) points vs. (5.99±0.94) points, (7.03±0.75) points vs. (9.13±0.88) points, respectively], and the differences were statistically significant (all P < 0.05). After treatment, SF-36 psychological dimension scores and SF-36 physiological dimension scores of patients in the observation group were higher than those in the control group [(78.12±6.22) points vs. (70.04±5.33) points, (79.98±7.48) points vs. (69.82±6.32) points, respectively], and the differences were statistically significant (all P < 0.05). Conclusion The combined application of bicycle exercise therapy and gabapentin can significantly improve the efficacy of haemodialysis patients with RLS, as well as improve the quality of sleep and quality of life.
- Bicycle exercise therapy,
- Gabapentin,
- Haemodialysis,
- Restless legs syndrome,
- Sleep quality,
- Quality of life

FullText(HTML)

References(21)

References

[1]	LIN X W, ZHANG J F, QIU M Y, et al. Restless legs syndrome in end stage renal disease patients undergoing hemodialysis[J]. BMC Neurol, 2019, 19(1): 47. doi: 10.1186/s12883-019-1265-y
[2]	SHAHGHOLIAN N, YOUSEFI H. The lived experiences of patients undergoing hemodialysis with the concept of care: A phenomenological study[J]. BMC Nephrol, 2018, 19(1): 338. doi: 10.1186/s12882-018-1138-4
[3]	WANG Z F, YU Z, LING Q, et al. Decentralized RLS with data-adaptive censoring for regressions over large-scale networks[J]. IEEE Trans Signal Process, 2018, 66(6): 1634-1648. doi: 10.1109/TSP.2018.2795594
[4]	丁墩, 马雪英, 李朋, 等. 尿毒症不宁腿岛叶功能连接异常的静息态功能磁共振研究[J]. 西安交通大学学报(医学版), 2020, 41(2): 172-176. https://www.cnki.com.cn/Article/CJFDTOTAL-XAYX202002004.htm DING D, MA X Y, LI P, et al. Resting state functional magnetic resonance study of abnormal functional connections in the insula of restless legs in uremia[J]. Journal of Xi ' an Jiaotong University (Medical Edition), 2020, 41(2): 172-176. https://www.cnki.com.cn/Article/CJFDTOTAL-XAYX202002004.htm
[5]	TAPOLYAI M, FALUDI M, BERTA K, et al. The association of overhydration with megafistulas in hemodialysis patients[J]. Ren Fail, 2019, 41(1): 440-445. doi: 10.1080/0886022X.2019.1614954
[6]	CHO J H, KANG S H, PARK H C, et al. Hemodialysis with cohort isolation to prevent secondary transmission during a COVID-19 outbreak in Korea[J]. J Am Soc Nephrol, 2020, 31(7): 1398-1408. doi: 10.1681/ASN.2020040461
[7]	彭志鹏, 张星平, 陈俊逾, 等. 基于匹兹堡睡眠质量指数的脾不藏意型及肾不藏志型不寐患者睡眠质量比较的临床研究[J]. 上海中医药杂志, 2020, 54(4): 65-67. https://www.cnki.com.cn/Article/CJFDTOTAL-SHZZ202004016.htm PENG Z P, ZHANG X P, CHEN J Y, et al. Clinical study on the comparison of sleep quality between patients with insomnia of spleen type and kidney type based on Pittsburgh sleep quality index[J]. Shanghai Journal of traditional Chinese medicine, 2020, 54(4): 65-67. https://www.cnki.com.cn/Article/CJFDTOTAL-SHZZ202004016.htm
[8]	BOWLINE I G, RUSSELL G B, BAGWELL B, et al. Temporal trends in fluid management with incremental hemodialysis[J]. Clin Nephrol, 2019, 92(4): 165-173. doi: 10.5414/CN109660
[9]	LIN Y T, WU P H, LIANG S S, et al. Protein-bound uremic toxins are associated with cognitive function among patients undergoing maintenance hemodialysis[J]. SCI Rep, 2019, 9(1): 20388. doi: 10.1038/s41598-019-57004-7
[10]	汤显靖, 丁玲. 脑内多巴胺神经递质表达对神经内科住院患者睡眠障碍的影响[J]. 海南医学院学报, 2019, 25(11): 829-833. https://www.cnki.com.cn/Article/CJFDTOTAL-HNYY201911008.htm TANG X J, DING L. Effect of dopamine neurotransmitter expression in brain on sleep disorders in inpatients of Department of Neurology[J]. Journal of Hainan Medical College, 2019, 25(11): 829-833. https://www.cnki.com.cn/Article/CJFDTOTAL-HNYY201911008.htm
[11]	FENG Y, LI Z, LIU J, et al. Association of short-term blood pressure variability with cardiovascular mortality among incident hemodialysis patients[J]. Ren Fail, 2018, 40(1): 259-264. doi: 10.1080/0886022X.2018.1456456
[12]	AYGVN F, KIYKIM E, AKTUĜLU-ZEYBEK Ç, et al. Treatment of maple syrup urine disease with high flow hemodialysis in a neonate[J]. Turk J Pediatr, 2019, 61(1): 107-110. doi: 10.24953/turkjped.2019.01.017
[13]	XIONG J, WANG M, ZHANG Y, et al. Association of geriatric nutritional risk index with mortality in hemodialysis patients: A meta-analysis of cohort studies[J]. Kidney Blood Press Res, 2018, 43(6): 1878-1889. doi: 10.1159/000495999
[14]	李林静, 李华旭, 闫东星, 等. N-乙酰半胱氨酸联合有氧运动对慢性阻塞性肺疾病稳定期患者肺功能、生活质量及血清氧化因子的影响[J]. 新乡医学院学报, 2018, 35(5): 407-410. https://www.cnki.com.cn/Article/CJFDTOTAL-XXYX201805013.htm LI L J, LI H X, YAN D X, et al. Effects of N acetylcysteine combined with aerobic exercise on pulmonary function, quality of life and serum oxidation factors in patients with stable chronic obstructive pulmonary disease[J]. Journal of Xinxiang Medical University, 2018, 35(5): 407-410. https://www.cnki.com.cn/Article/CJFDTOTAL-XXYX201805013.htm
[15]	FITZPATRICK J, SOZIO S M, JAAR B G, et al. Association of abdominal adiposity with cardiovascular mortality in incident hemodialysis[J]. Am J Nephrol, 2018, 48(6): 406-414. doi: 10.1159/000494281
[16]	张兴, 廖瑛, 周君, 等. 核心区肌群稳定性训练防治膝骨关节炎的意义[J]. 中南医学科学杂志, 2020, 48(1): 102-104, 108. https://www.cnki.com.cn/Article/CJFDTOTAL-HYYY202001029.htm ZHANG X, LIAO Y, ZHOU J, et al. Significance of core muscle group stability training in the prevention and treatment of knee osteoarthritis[J]. Zhongnan Journal of medical science, 2020, 48(1): 102-104, 108. https://www.cnki.com.cn/Article/CJFDTOTAL-HYYY202001029.htm
[17]	CHOI H M, KIM T H. A randomized controlled trial of moderate-intensity circuit band resistance exercise program improve aerobic exercise ability in older adults[J]. Iran J Public Health, 2019, 48(5): 971-973.
[18]	薄文婷, 蔡鲁青, 牛国丽. 坐位脚踏车运动疗法在血液透析患者透析过程中应用的效果评价[J]. 中华现代护理杂志, 2020, 26(22): 3081-3084. doi: 10.3760/cma.j.cn115682-20200421-02911 BO W T, CAI L Q, NIU G L. Effect evaluation of sitting bicycle exercise therapy in hemodialysis patients[J]. Chinese Journal of modern nursing, 2020, 26(22): 3081-3084. doi: 10.3760/cma.j.cn115682-20200421-02911
[19]	胡慧英, 张征宇. 运动干预在老年糖尿病周围神经病变患者中的应用效果[J]. 中华全科医学, 2020, 18(5): 769-772. doi: 10.16766/j.cnki.issn.1674-4152.001352 HU H Y, ZHANG Z Y. Effect of exercise intervention on elderly patients with diabetes peripheral neuropathy[J]. Chinese general practice, 2020, 18(5): 769-772. doi: 10.16766/j.cnki.issn.1674-4152.001352
[20]	周雨婷, 林亚妹, 王娜, 等. 有氧运动疗法对维持性血液透析患者透析充分性及营养状态影响的研究进展[J]. 现代医学, 2019, 47(9): 1177-1179. https://www.cnki.com.cn/Article/CJFDTOTAL-TDYX201909031.htm ZHOU Y T, LIN Y M, WANG N, et al. Research progress of aerobic exercise therapy on dialysis adequacy and nutritional status of maintenance hemodialysis patients[J]. Modern medicine, 2019, 47(9): 1177-1179. https://www.cnki.com.cn/Article/CJFDTOTAL-TDYX201909031.htm
[21]	皮治兵, 林海, 彭宇, 等. 加巴喷丁辅助治疗颈肩及颜面部带状疱疹后神经痛及对T淋巴细胞的影响[J]. 中华全科医学, 2020, 18(1): 45-47. doi: 10.16766/j.cnki.issn.1674-4152.001164 PI Z B, LIN H, PENG Y, et al. Gabapentin adjuvant treatment of post herpetic neuralgia in neck, shoulder and face and its effect on T lymphocytes[J]. Chinese general practice, 2020, 18(1): 45-47. doi: 10.16766/j.cnki.issn.1674-4152.001164

Relative Articles

Supplements(0)

Cited By

Proportional views

Proportional views

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Tables(3)

Get Citation

PDF

XML

Article Metrics

Article views (238) PDF downloads(2)

Application value of bicycle exercise therapy and gabapentin in the treatment of haemodialysis patients with restless legs syndrome

doi: 10.16766/j.cnki.issn.1674-4152.002456

Abstract

References

Proportional views

Catalog

通讯作者: 陈斌, bchen63@163.com

Article Metrics

Proportional views

Related

Application value of bicycle exercise therapy and gabapentin in the treatment of haemodialysis patients with restless legs syndrome

doi: 10.16766/j.cnki.issn.1674-4152.002456

Abstract

References

Proportional views

Catalog

通讯作者: 陈斌, bchen63@163.com

Article Metrics

Proportional views

Related

Export File

Citation

Format

Content