Volume 20 Issue 5
May  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(5): 844-847
XU Bao-cai, CHEN Wei. Evaluation of the effect of LEI's Yinzhan ginger moxibustion combined with Buhuo Shengtu therapy on ulcerative colitis in the remission stage[J]. Chinese Journal of General Practice, 2022, 20(5): 844-847. doi: 10.16766/j.cnki.issn.1674-4152.002469
Citation: XU Bao-cai, CHEN Wei. Evaluation of the effect of LEI's Yinzhan ginger moxibustion combined with Buhuo Shengtu therapy on ulcerative colitis in the remission stage[J]. Chinese Journal of General Practice, 2022, 20(5): 844-847. doi: 10.16766/j.cnki.issn.1674-4152.002469
shu

Evaluation of the effect of LEI's Yinzhan ginger moxibustion combined with Buhuo Shengtu therapy on ulcerative colitis in the remission stage

doi: 10.16766/j.cnki.issn.1674-4152.002469

  • Department of Gastroenterology, Quzhou Hospital of Traditional Chinese Medicine, Quzhou, Zhejiang 324002, China

Funds:

 国中医药人教函〔2019〕36号

 2018ZA129

 2020ZB289

 2021ZB324

 2015C33274

  • Received Date: 2021-09-21
    Available Online: 2022-09-05
    Abstract
  •   Objective  To evaluate the effect and possible mechanism of LEI's Yinzhan ginger-padded moxibustion combined with Buhuo Shengtu therapy in the treatment of ulcerative colitis (UC) in the remission stage.  Methods  From January 2017 to June 2020, 73 UC patients in the Department of Gastroenterology, Department of Anus and Intestine of Quzhou Hospital of Traditional Chinese Medicine were randomly divided into two groups according to random number table method. The observation group(n=36) was treated with LEI's Yinzhan ginger-padded moxibustion combined with Buhuo Shengtu therapy, whereas the control group(n=37) was treated with mesalazine. The course of treatment was 4 weeks. The intervention effect and mechanism of the two groups were evaluated.  Results  After treatment, the efficacy of the observation group was better than that of the control group (Z=2.352, P=0.019). The symptom score of the observation group was lower than that of the control group [(26.04±5.37) scores vs. (32.23±6.45) scores, P < 0.05]. The Mayo score in the observation group was lower than that in the control group [(5.32±1.07) scores vs. (6.75±1.56) scores, P < 0.05]. The levels of serum inflammatory factors (CRP, TNF-α and IL-17) were lower in the observation group than in the control group (all P < 0.05). The levels of NK, CD4+ and CD4+/CD8+ were higher in the observation group than in the control group (all P < 0.05). The IgG and IgM values were significantly lower in the observation group than those in the control group (all P < 0.05).  Conclusion  LEI's Yinzhan ginger-padded moxibustion combined with Buhuo Shengtu therapy has a definite effect on the treatment of UC in the remission stage, and its mechanism may be related to the regulation of intestinal inflammation and immune function.

     

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    • References(16)
  • [1]
    程慧, 冯晓莹, 徐华. 炎症性肠病242例临床分析[J]. 中国医科大学学报, 2017, 46(11): 1039-1041. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGYK201711018.htm

    CHENG H, FENG X Y, XU H. Clinical analysis of 242 inflammatory bowel disease cases[J]. Journal of China Medical University, 2017, 46(11): 1039-1041. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGYK201711018.htm
    [2]
    田洁, 王亮, 徐宁. 美沙拉嗪、枯草杆菌二联活菌肠溶胶囊联合用于轻、中度溃疡性结肠炎患者的疗效观察[J]. 实用药物与临床, 2019, 23(3): 296-299. https://www.cnki.com.cn/Article/CJFDTOTAL-LYLC201903021.htm

    TIAN J, WANG L, XU N. Efficacy of mesalazine combined with Bacillus subtilis enteric-coated capsules in patients with mild to moderate ulcerative colitis[J]. Drugs for use and clinical practice, 2019, 23(3): 296-299. https://www.cnki.com.cn/Article/CJFDTOTAL-LYLC201903021.htm
    [3]
    毕文静, 柳越冬. 中医治疗慢性非特异性溃疡性结肠炎的研究近况[J]. 辽宁中医杂志, 2017, 44(2): 422-425. https://www.cnki.com.cn/Article/CJFDTOTAL-LNZY201702068.htm

    BI W J, LIU Y D. Recent advances in the study of traditional Chinese medicine in the treatment of chronic non-specific ulcerative colitis[J]. Liaoning J Tradit Chin Med, 2017, 44(2): 422-425. https://www.cnki.com.cn/Article/CJFDTOTAL-LNZY201702068.htm
    [4]
    邱根祥, 许宝才, 方昉, 等. 衢州雷氏医学源流与学术特色初探[J]. 浙江中医杂志, 2017, 52(11): 781-783. https://www.cnki.com.cn/Article/CJFDTOTAL-ZJZZ201711004.htm

    QIU G Y, XU B C, FANG F, et al. The origin and academic characteristics of Lehrer' s medicine in Quzhou[J]. Zhejiang Journal of Traditional Chinese medicine, 2017, 52(11): 781-783. https://www.cnki.com.cn/Article/CJFDTOTAL-ZJZZ201711004.htm
    [5]
    中华医学会消化学分会炎症性肠病学组. 炎症性肠病诊断与治疗的共识意见(2018年·北京)[J]. 中国实用内科杂志, 2018, 38(9): 796-813. https://www.cnki.com.cn/Article/CJFDTOTAL-SYNK201809007.htm

    Inflammatory bowel disease group, digestive society, Chinese Medical Association. Consensus on inflammatory bowel disease diagnosis and treatment (Beijing, 2018)[J]. Chinese Journal of Practical Internal Medicine, 2018, 38(9): 796-813. https://www.cnki.com.cn/Article/CJFDTOTAL-SYNK201809007.htm
    [6]
    中国中西医结合学会消化系统疾病专业委员会. 溃疡性结肠炎中西医结合诊疗共识意见[J]. 中国中西医结合消化杂志, 2018, 26(2): 105-120. https://www.cnki.com.cn/Article/CJFDTOTAL-ZXPW201802001.htm

    The gastrointestinal disease committee of the Chinese Society of Integrated Traditional Chinese and Western medicine. A ulcerative colitis consensus on the diagnosis and treatment of integrated Chinese and Western medicine[J]. 中国中西医结合消化杂志, 2018, 26(2): 105-120. https://www.cnki.com.cn/Article/CJFDTOTAL-ZXPW201802001.htm
    [7]
    WANG X R, ZHU Y G, ZHANG M L, et al. The shifted balance beteen circulating follicular regulatory T cells and follicular helper T cells in patients with ulcerative colitis[J]. Clin Sci, 2017, 131(24): 2933-2945. doi: 10.1042/CS20171258
    [8]
    张冰, 谢晶日, 孙涛. 中药内服与灌肠治疗活动期溃疡性结肠炎的临床疗效[J]. 中华全科医学, 2019, 17(2): 284-287. doi: 10.16766/j.cnki.issn.1674-4152.000662

    ZHANG B, XIE J R, SUN T. Clinical efficacy of oral Chinese medicine and enema in the treatment of active ulcerative colitis[J]. Chinese general practice, 2019, 17(2): 284-287. doi: 10.16766/j.cnki.issn.1674-4152.000662
    [9]
    丁栋, 李佳妮, 齐冉, 等. 溃疡性结肠炎的研宄进展[J]. 药学研究, 2017, 36(7): 404-408.

    DING D, LI J N, QI R, et al. Progress in ulcerative colitis research[J]. Pharmaceutical Research, 2017, 36(7): 404-408.
    [10]
    翁湘涛, 胡月, 廖柳, 等. 参苓白术散加减对比西药治疗溃疡性结肠炎的疗效和安全性meta分析[J]. 中国实验方剂学杂志, 2017, 23(10): 205-210. https://www.cnki.com.cn/Article/CJFDTOTAL-ZSFX201710034.htm

    WEN X T, HU Y, LIAO L, et al. Meta-analysis of the efficacy and safety of Shenlingbaizhu powder in the treatment of ulcerative colitis disease[J]. Chinese Journal of experimental prescription, 2017, 23(10): 205-210. https://www.cnki.com.cn/Article/CJFDTOTAL-ZSFX201710034.htm
    [11]
    肖迅, 张燕. 中药有效成分/有效部位治疗溃疡性结肠炎的研究进展[J]. 中药药理与临床, 2017, 33(3): 219-223. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYYL201703067.htm

    XIAO X, ZHANG Y. Research progress of effective components and active parts of Chinese herbal medicine in the treatment of ulcerative colitis[J]. Pharmacology and clinic of Chinese materia medica, 2017, 33(3): 219-223. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYYL201703067.htm
    [12]
    许宝才, 陈刚, 吴世泉. 陈伟主任医师论治脾胃病的学术经验[J]. 中国中医急症, 2018, 27(10): 1838-1841. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYJZ201810045.htm

    XU B C, CHEN G, WU S Q. Professor Chen Wei' s academic experience in treating spleen and stomach diseases[J]. Chinese traditional medicine emergency, 2018, 27(10): 1838-1841. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYJZ201810045.htm
    [13]
    李宛蓉, 李博, 赵天易, 等. 古代灸疗医案中的灸法应用规律研究[J]. 中华中医药杂志, 2019, 34(3): 1181-1183. https://www.cnki.com.cn/Article/CJFDTOTAL-BXYY201903088.htm

    LI W R, LI B, ZHAO T Y, et al. Study on the law of application of Moxibustion in ancient medical records[J]. Chin J Tradit Chin Med Pharm, 2019, 34(3): 1181-1183. https://www.cnki.com.cn/Article/CJFDTOTAL-BXYY201903088.htm
    [14]
    许宝才, 邱根祥, 陈伟, 等. 雷氏补火生土法配合脐疗治疗腹泻型肠易激综合征临床研究[J]. 新中医, 2018, 50(6): 195-198. https://www.cnki.com.cn/Article/CJFDTOTAL-REND201806058.htm

    XU B C, QIU G Y, CHEN Q, et al. Clinical study on the treatment of diarrhea-predominant irritable bowel syndrome (IBS) with Lei' s method of reinforcing fire and generating Earth combined with navel therapy[J]. New Chinese medicine, 2018, 50(6): 195-198. https://www.cnki.com.cn/Article/CJFDTOTAL-REND201806058.htm
    [15]
    SHEN Z H, ZHU C X, QUAN Y S, et al. Relationship between intestinal microbiota and ulcerative colitis: Mechanisms and clinical application of probiotics and fecal microbiota transplantation[J]. World J Gastroenterol, 2018, 24(1): 5-14. doi: 10.3748/wjg.v24.i1.5
    [16]
    甄建华, 黄光瑞. 溃疡性结肠炎病因和发病机制的现代医学研究进展[J]. 世界华人消化杂志, 2019, 27(4): 245-251. https://www.cnki.com.cn/Article/CJFDTOTAL-XXHB201904006.htm

    ZHEN J H, HUANG G R. Advances in modern medical research on the etiology and pathogenesis of ulcerative colitis[J]. World Journal of Chinese digestion, 2019, 27(4): 245-251. https://www.cnki.com.cn/Article/CJFDTOTAL-XXHB201904006.htm
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