Treatment of severe benign central airway stenosis with laser under bronchoscope

LI Meng-yi; GONG Bei-lei; LI Wei; SHEN Yuan-bing; WU Jing; XU Yuan-yuan; ZHANG Ya-ting; CHEN Yu-qing

doi:10.16766/j.cnki.issn.1674-4152.002488

Volume 20 Issue 6

Jun. 2022

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Article Navigation > Chinese Journal of General Practice > 2022 > 20(6): 923-926

LI Meng-yi, GONG Bei-lei, LI Wei, SHEN Yuan-bing, WU Jing, XU Yuan-yuan, ZHANG Ya-ting, CHEN Yu-qing. Treatment of severe benign central airway stenosis with laser under bronchoscope[J]. Chinese Journal of General Practice, 2022, 20(6): 923-926. doi: 10.16766/j.cnki.issn.1674-4152.002488

Citation:

LI Meng-yi, GONG Bei-lei, LI Wei, SHEN Yuan-bing, WU Jing, XU Yuan-yuan, ZHANG Ya-ting, CHEN Yu-qing. Treatment of severe benign central airway stenosis with laser under bronchoscope[J]. Chinese Journal of General Practice, 2022, 20(6): 923-926. doi: 10.16766/j.cnki.issn.1674-4152.002488

Citation:

LI Meng-yi, GONG Bei-lei, LI Wei, SHEN Yuan-bing, WU Jing, XU Yuan-yuan, ZHANG Ya-ting, CHEN Yu-qing. Treatment of severe benign central airway stenosis with laser under bronchoscope[J]. Chinese Journal of General Practice, 2022, 20(6): 923-926. doi: 10.16766/j.cnki.issn.1674-4152.002488

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Treatment of severe benign central airway stenosis with laser under bronchoscope

doi: 10.16766/j.cnki.issn.1674-4152.002488

LI Meng-yi¹
, GONG Bei-lei^{1, 2, 3}
, LI Wei^{1, 2, 3}
, SHEN Yuan-bing^{1, 2, 3}
, WU Jing^{1, 2, 3}
, XU Yuan-yuan^{1, 2, 3}
, ZHANG Ya-ting¹
, CHEN Yu-qing^{1, 2, 3
,
,}

1.
Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

KJ2019A0389

202004j07020010

S202010367035

Received Date: 2021-10-08
Available Online: 2022-09-21

Abstract

Abstract

Objective The aetiology of benign central airway stenosis is complex, and the treatment is challenging. This paper discusses the safety and effectiveness of laser under bronchoscope for treating severe benign hyperplasia central airway stenosis. Methods Total 23 patients with benign hyperplasia central airway stenosis treated by laser under bronchoscope in the First Affiliated Hospital of Bengbu Medical College from March 2016 to September 2021 were studied retrospectively. The improvement of airway patency and quality of life were evaluated by using the modified Medical Research Council Dyspnea Scale (mMRC) and short form 36 questionnaire (SF-36), the effectiveness of treatment was dynamically evaluated. The complications were monitored, and the safety was evaluated. Results The average age of patients was (57.43±10.85) years old, and the male-to-female ratio was 1.87 5∶ 1. Previous tracheotomy was the most common cause of stenosis (56.5%), followed by endotracheal intubation (43.5%). The symptoms of 23 patients (23/23, 100.0%) were improved, the airway was unobstructed, and the quality of life was improved. The SF-36 score [(107.02±10.72) points] was significantly higher than that before operation [(70.34±6.17) points, t=-19.877, P < 0.001], and the mMRC score decreased significantly (P < 0.001). There were no intraoperative and postoperative complications. Twenty-three patients were followed up for 1-60 months, with an average of 14.39 months and a median of 8.0 (4.0, 23.0) months. Seventeen cases (17/23, 73.9%) had re-stenosis during follow-up, of which 12 cases (12/17, 70.6%) needed interventional treatment. Conclusion Laser ablation of benign hyperplasia central airway stenosis through endoscopy is safe and effective, which shows the significant improvement of patients' respiratory function and quality of life, especially for critically ill patients.
- Laser,
- Bronchoscope,
- Benign central airway stenosis

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References

[1]	OBERG C L, HOLDEN V K, CHANNICK C L. Benign central airway obstruction[J]. Semin Respir Crit Care Med, 2018, 39(6): 731-746. doi: 10.1055/s-0038-1676574
[2]	WANG T, ZHANG J, QIU X J, et al. Scarring airway stenosis in chinese adults: Characteristics and interventional bronchoscopy treatment[J]. Chin Med J(Engl), 2018, 131(3): 276-281.
[3]	蒋慧, 邵乐健, 乔伟, 等. 原发性气管-支气管淀粉样变2例报道并文献复习[J]. 中华全科医学, 2019, 17(7): 1245-1248. doi: 10.16766/j.cnki.issn.1674-4152.000912 JIANG H, SHAO L J, QIAO W, et al. Primary trochehronehiay amyloidosis: Two cases report and literature review[J]. Chinese Journal of General Practice, 2019, 17(7): 1245-1248. doi: 10.16766/j.cnki.issn.1674-4152.000912
[4]	SHAYAN N A, ARSLAN U E, HOOSHMAND A M, et al. The short form health survey (SF-36): Translation and validation study in afghanistan[J]. East Mediterr Health J, 2020, 26(8): 899-908. doi: 10.26719/emhj.20.064
[5]	中华医学会呼吸病学分会. 良性中心气道狭窄经支气管镜介入诊治专家共识[J]. 中华结核和呼吸杂志, 2017, 40(6): 408-418. doi: 10.3760/cma.j.issn.1001-0939.2017.06.004 Chinese Society of Respiratory Diseases. Expert consensus on the diagnosis and treatment of benign central airway stenosis by bronchoscopy[J]. Chinese Journal of Tuberculosis and Respiratory Diseases, 2017, 40(6): 408-418. doi: 10.3760/cma.j.issn.1001-0939.2017.06.004
[6]	ÖZDEMIR C, KOCATVRK C I, SÖKVCV S N, et al. Endoscopic and surgical treatment of benign tracheal stenosis: A multidisciplinary team approach[J]. Ann Thorac Cardiovasc Surg, 2018, 24(6): 288-295. doi: 10.5761/atcs.oa.18-00073
[7]	MAURIZI G, VANNI C, RENDINA E A, et al. Surgery for laryngotracheal stenosis: Improved results[J]. J Thorac Cardiovasc Surg, 2021, 161(3): 845-852. doi: 10.1016/j.jtcvs.2020.12.023
[8]	SICILIANI A, RENDINA E A, IBRAHIM M. State of the art in tracheal surgery: A brief literature review[J]. Multidiscip Respir Med, 2018, 13(1): 34. doi: 10.1186/s40248-018-0147-2
[9]	LEWIS S, EARLEY M, ROSENFELD R, et al. Systematic review for surgical treatment of adult and adolescent laryngotracheal stenosis[J]. Laryngoscope, 2017, 127(1): 191-198. doi: 10.1002/lary.26151
[10]	TONG L R, ZHANG K D, HUANG H D, et al. Comparison of the efficacy of four endobronchial ablation techniques in dogs[J]. Exp Ther Med, 2017, 13(1): 169-177. doi: 10.3892/etm.2016.3946
[11]	LEE G S, IRACE A, RAHBAR R. The efficacy and safety of the flexible fiber CO₂ laser delivery system in the endoscopic management of pediatric airway problems: Our long term experience[J]. Int J Pediatr Otorhinolaryngol, 2017, 97(1): 218-222.
[12]	EKBOM D C, BAYAN S L, GOATES A J, et al. Endoscopic wedge excisions with CO₂ laser for subglottic stenosis[J]. Laryngoscope, 2021, 131(4): E1062-E1066.
[13]	MARVIN K, SCHWARTZ I, UTZ E, et al. Effects of fractional CO₂ laser treatment on subglottic scar in a rabbit model[J]. Otolaryngol Head Neck Surg, 2021, 165(1): 137-141. doi: 10.1177/0194599820978256
[14]	VERRET D J, JATEGAONKAR A, HELMAN S, et al. Holmium laser for endoscopic treatment of benign tracheal stenosis[J]. Int Arch Otorhinolaryngol, 2018, 22(3): 203-207. doi: 10.1055/s-0037-1604201
[15]	MAREL M, TREFNY M, PETRIK F, et al. Comparison of two groups of patients with benign airway stenosis from 1998-2003 and 2014-2016 years[J]. Eur Respir J, 2018, 52(s62): 4172.
[16]	DESHMUKH A, JADHAV S, WADGOANKAR V, et al. Airway management and bronchoscopic treatment of subglottic and tracheal stenosis using holmium laser with balloon dilatation[J]. Indian J Otolaryngol Head Neck Surg, 2019, 71(Suppl 1): 453-458.
[17]	王成, 刘庆华, 赵娜, 等. 局麻下支气管镜钬激光治疗大气道狭窄的临床评价[J]. 中国内镜杂志, 2020, 26(3): 77-81. doi: 10.3969/j.issn.1007-1989.2020.03.014 WANG C, LIU Q H, ZHAO N, et al. Application and safety evaluation of holmium laser in the central airway obstruction[J]. China Journal of Endoscopy, 2020, 26(3): 77-81. doi: 10.3969/j.issn.1007-1989.2020.03.014

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Treatment of severe benign central airway stenosis with laser under bronchoscope

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