Volume 20 Issue 6
Jun.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(6): 978-981
GUO Jia-jia, MA Sheng-yin, LIU Li-hua, GAO Jun, GONG Feng. Risk factors of cardiovascular disease in maintenance haemodialysis patients[J]. Chinese Journal of General Practice, 2022, 20(6): 978-981. doi: 10.16766/j.cnki.issn.1674-4152.002503
Citation: GUO Jia-jia, MA Sheng-yin, LIU Li-hua, GAO Jun, GONG Feng. Risk factors of cardiovascular disease in maintenance haemodialysis patients[J]. Chinese Journal of General Practice, 2022, 20(6): 978-981. doi: 10.16766/j.cnki.issn.1674-4152.002503
shu

Risk factors of cardiovascular disease in maintenance haemodialysis patients

doi: 10.16766/j.cnki.issn.1674-4152.002503

  • Department of Nephrology, the Third Affiliated Hospital of Bengbu Medical College, Suzhou, Anhui 234000, China

Funds:

 1704f0804050

 2020byzd363

  • Received Date: 2021-03-28
    Available Online: 2022-09-21
    Abstract
  •   Objective  To study the risk factors of cardiovascular disease in maintenance haemodialysis patients.  Methods  A total of 126 patients in the uremic phase of chronic renal insufficiency who underwent maintenance haemodialysis in the haemodialysis unit of the Third Affiliated Hospital of Bengbu Medical College from January 2019 to October 2020 were retrospectively enrolled.They were divided into the cardiovascular complication group (n=74) and group without cardiovascular complications (n=52) according to whether the patients developed cardiovascular disease.The differences of general information and laboratory examination indexes between the two groups were compared, and the risk factors of cardiovascular disease in maintenance haemodialysis patients were analysed by binary logistic regression.  Results  Age, long dialysis age, serum uric acid, homocysteine, high sensitivity C-reactive protein and interleukin-6 levels were higher, whereas prealbumin, high-density lipoprotein cholesterol and serum magnesium levels were lower in the group with cardiovascular complications than in the group without cardiovascular complications (all P < 0.05).Binary logistic regression analysis showed that age, dialysis age, hyperhomocysteinemia, hyperuricemia, high levels of high-sensitivity C-reactive protein and interleukin-6 were independent risk factors for the development of cardiovascular disease in maintenance haemodialysis patients (OR=1.441, P=0.029;OR=2.212, P=0.019;OR=1.384, P=0.030;OR=5.056, P < 0.001;OR=3.163, P=0.013;OR=3.802, P=0.009).  Conclusion  Old age, long dialysis age, hyperhomocysteinemia, hyperuricemia, high levels of high-sensitivity C-reactive protein and interleukin-6 may be independent risk factors for cardiovascular disease in maintenance haemodialysis patients.

     

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