Volume 20 Issue 6
Jun.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(6): 986-989
QIAN Yan-qing, SUN Yun. Effect of Yishen Quyu Decoction combined with Western medicine in the treatment of threatened abortion with uterine haematocele and its influence on ultrasound indexes[J]. Chinese Journal of General Practice, 2022, 20(6): 986-989. doi: 10.16766/j.cnki.issn.1674-4152.002505
Citation: QIAN Yan-qing, SUN Yun. Effect of Yishen Quyu Decoction combined with Western medicine in the treatment of threatened abortion with uterine haematocele and its influence on ultrasound indexes[J]. Chinese Journal of General Practice, 2022, 20(6): 986-989. doi: 10.16766/j.cnki.issn.1674-4152.002505
shu

Effect of Yishen Quyu Decoction combined with Western medicine in the treatment of threatened abortion with uterine haematocele and its influence on ultrasound indexes

doi: 10.16766/j.cnki.issn.1674-4152.002505

  • Department of Gynecology, Wenzhou Traditional Chinese Medicine Hospital, Wenzhou, Zhejiang 325000, China

Funds:

 2019ZB121

  • Received Date: 2021-11-30
    Available Online: 2022-09-21
    Abstract
  •   Objective  To study the effect of Yishen Quyu Decoction on threatened abortion with uterine haematocele, so as to provide basis for clinical treatment.  Methods  From January 2019 to June 2020, 126 patients with threatened abortion and intrauterine haematocele admitted in Wenzhou Traditional Chinese Medicine Hospital were selected and randomly divided into the Western medicine group (63 cases) and combined group (63 cases).The Western medicine group was treated with low-molecular-weight heparin combined with didroxyprogesterone, and the combined group was treated with Yishen Quyu Decoction and Western medicine.The traditional Chinese medicine (TCM) syndrome score, ultrasound index, pregnancy outcome, sex hormone, carbohydrate antigen 125(CA125) and inflammatory factor levels of the two groups were compared.  Results  After treatment, the main symptom and secondary symptom scores of the two groups were significantly decreased, and the scores of the combined group were lower than those of the Western medicine group (all P < 0.05).After treatment, the ultrasound indexes of the two groups were significantly improved.The end diastolic blood flow velocity (EDV) and peak systolic blood flow velocity (PSV) levels of the combined group were higher than those of the Western medicine group, and resistance index (RI) was lower than that of the Western Medicine group (all P < 0.05).After treatment, the levels of serum sex hormone and CA125 in the two groups were significantly improved.The levels of progesterone (P), estradiol (E2) and human chorionic gonadotropin (HCG) in the combined group were significantly higher than those in the control group, and the CA125 level in the combined group was lower than that in Western medicine group (all P < 0.05).After treatment, the levels of inflammatory factors in both groups were significantly improved.The levels of IL-4, IL-10, INF-γ and IL-2 in the combined group were lower than those in the Western medicine group (all P < 0.05).The success rate of foetus preservation in the combined group was 93.65%, which was only 80.95% in the Western medicine group (P < 0.05).  Conclusion  Yishen Quyu Decoction combined with Western medicine can significantly improve the clinical symptoms of threatened abortion patients with uterine haematocele, regulate the levels of serum sex hormones and Th1/Th2 cytokines, improve the blood supply of the uterine artery and reduce the CA125 level, and has a higher success rate of foetal protection.

     

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