Volume 20 Issue 6
Jun.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(6): 993-995
FANG Xu-lan, WANG Bing-song, LI Zhen, LAN Ting. Analysis of the epidemiological characteristics and pathogenic detection results of hand, foot and mouth disease in a tertiary hospital in Wuhu City from 2020 to 2021[J]. Chinese Journal of General Practice, 2022, 20(6): 993-995. doi: 10.16766/j.cnki.issn.1674-4152.002507
Citation: FANG Xu-lan, WANG Bing-song, LI Zhen, LAN Ting. Analysis of the epidemiological characteristics and pathogenic detection results of hand, foot and mouth disease in a tertiary hospital in Wuhu City from 2020 to 2021[J]. Chinese Journal of General Practice, 2022, 20(6): 993-995. doi: 10.16766/j.cnki.issn.1674-4152.002507
shu

Analysis of the epidemiological characteristics and pathogenic detection results of hand, foot and mouth disease in a tertiary hospital in Wuhu City from 2020 to 2021

doi: 10.16766/j.cnki.issn.1674-4152.002507

  • Department of Pediatrics, the First People ' s Hospital of Wuhu, Wuhu, Anhui 241000, China

Funds:

 AHWJ2021b084

  • Received Date: 2021-12-01
    Available Online: 2022-09-21
    Abstract
  •   Objective  To analyse the epidemiological and pathogenic characteristics of hand, foot and mouth disease in a tertiary hospital in Wuhu City from 2020 to 2021 and to provide a reference for the city to formulate prevention and control strategies for hand, foot and mouth disease.  Methods  Epidemiological analysis was performed on 200 samples of hand, foot and mouth disease, and pathogenic detection was performed by real-time fluorescent quantitative PCR.  Results  In 200 cases of hand, foot and mouth disease, the male-to-female ratio was 1.9:1.Scattered children under 3 years of age accounted for the highest proportion of the total number of people, and 81.0% were at high risk of contracting the disease.From 2020 to 2021, the pathogens of hand, foot and mouth disease in this city were mainly CoxA16(96 cases, 48.0%) and EV71(90 cases, 45.0%), showing a common epidemic situation.In terms of detection rate, throat swabs were the highest (38.5%), and herpes fluid was the lowest (29.0%).However, the detection rates of various viruses were relatively close (P>0.05).Among the 200 cases, 133 cases were normal type (66.5%) and 67 cases were severe syndrome type (33.5%).Compared with the normal type, the incidence of symptoms such as body temperature>39℃, arrhythmia, impatience, limb shaking and neck stiffness in severe group were significantly increased (all P < 0.05).  Conclusion  The distribution of hand, foot and mouth disease has certain differences in different populations, times and regions.CoxA16 and EV71 enterovirus types have become the dominant virus types of hand, foot and mouth disease.Therefore, it is necessary to further strengthen its pathogenic monitoring, and at the same time conduct related knowledge education to improve the doctor's ability to identify case manifestations.

     

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