Volume 20 Issue 6
Jun.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(6): 1016-1018
MAO Ying, WANG Fang, CHI Ju-fang, ZHONG Fang-fang. Application value of transcranial Doppler ultrasound foaming test in screening cryptogenic stroke caused by patent foramen ovale[J]. Chinese Journal of General Practice, 2022, 20(6): 1016-1018. doi: 10.16766/j.cnki.issn.1674-4152.002513
Citation: MAO Ying, WANG Fang, CHI Ju-fang, ZHONG Fang-fang. Application value of transcranial Doppler ultrasound foaming test in screening cryptogenic stroke caused by patent foramen ovale[J]. Chinese Journal of General Practice, 2022, 20(6): 1016-1018. doi: 10.16766/j.cnki.issn.1674-4152.002513
shu

Application value of transcranial Doppler ultrasound foaming test in screening cryptogenic stroke caused by patent foramen ovale

doi: 10.16766/j.cnki.issn.1674-4152.002513
  • 1.

    Special Examination Room of Shaoxing People's Hospital, Shaoxing, Zhejiang 312000, China

Funds:

 2021KY360

  • Received Date: 2021-12-03
    Available Online: 2022-09-21
    Abstract
  •   Objective  To analyse the application value of transcranial Doppler ultrasound foaming test (C-TCD) in screening cryptogenic stroke (CS) caused by patent foramen ovale (PFO).  Methods  A total of 204 patients with CS treated in Shaoxing People's Hospital from January 2017 to June 2021 were examined by C-TCD and transoesophageal echocardiography (TEE), and the positive detection rate of PFO was compared. According to the PFO detection of C-TCD, the positive patients were included in the positive group, and the negative patients in the negative group. The microbubble signal classification of the patients in the positive group was analysed, and the imaging characteristics of the vascular distribution areas (anterior circulation, posterior circulation, combined anterior and posterior circulation, anterior cerebral artery, middle cerebral artery and vertebrobasilar artery) and each region were compared between the two groups.  Results  The positive rate of PFO in C-TCD was 55.39% (113/204), which was higher than that in TEE (42.65%, 87/204, P < 0.05). A total of 113 cases of PFO were positive in C-TCD, including 26 cases of grade 0 (23.01%), 34 cases of grade Ⅰ (30.09%), 27 cases of grade Ⅱ (23.89%) and 26 cases of grade Ⅲ (23.01%). There was no significant difference in the distribution of anterior circulation, posterior circulation, combined anterior and posterior circulation, anterior cerebral artery, middle cerebral artery and vertebrobasilar artery in the positive and negative groups (P>0.05). The detection rate of cortical/subcortical area in the positive group was 57.52%, which was higher than that in the negative group (27.59%), P < 0.05. The detection rate of deep grey matter in the positive group was 22.12%, which was lower than that in the negative group (40.23%), P < 0.05. The detection rate of infratentorial area in the positive group was 14.16%, which was close to that in the negative group (16.09%), P>0.05.  Conclusion  C-TCD has a certain application value in the screening of CS caused by PFO. Patients' lesions are mostly distributed in cortical/subcortical areas, which can be used as a means of screening the aetiology of CS.

     

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