Volume 20 Issue 7
Jul.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(7): 1098-1101
HUANG Jin, LIU Xun-qin, LI Ang-qing, CHENG Cen, LIU Xue-sheng, GU Er-wei. Influence of individualised blood pressure management strategy on postoperative acute kidney injury in the elderly patients who underwent gastrointestinal surgery[J]. Chinese Journal of General Practice, 2022, 20(7): 1098-1101. doi: 10.16766/j.cnki.issn.1674-4152.002532
Citation: HUANG Jin, LIU Xun-qin, LI Ang-qing, CHENG Cen, LIU Xue-sheng, GU Er-wei. Influence of individualised blood pressure management strategy on postoperative acute kidney injury in the elderly patients who underwent gastrointestinal surgery[J]. Chinese Journal of General Practice, 2022, 20(7): 1098-1101. doi: 10.16766/j.cnki.issn.1674-4152.002532
shu

Influence of individualised blood pressure management strategy on postoperative acute kidney injury in the elderly patients who underwent gastrointestinal surgery

doi: 10.16766/j.cnki.issn.1674-4152.002532
  • 1.

    Department of Anesthesiology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China

Funds:

 1804h08020267

  • Received Date: 2021-10-24
    Available Online: 2022-09-23
    Abstract
  •   Objective  To explore the effect of individualised blood pressure management strategy on postoperative acute kidney injury (AKI) in elderly patients who underwent gastrointestinal surgery to provide certain clinical data for reducing the incidence of AKI.  Methods  A total of 166 patients who underwent elective gastrointestinal surgery in the First Affiliated Hospital of Anhui Medical University from September 2018 to December 2019 were selected. The patients were randomly divided into individualised blood pressure management group (IM group, n=84) and standard blood pressure management strategy group (CON group, n=82). The mean arterial pressure (MAP), systolic blood pressure (SBP), diastolic blood pressure (DBP), creatinine (CRE), blood urea nitrogen (BUN), estimated glomerular filtration rate (eGFR) and incidence of AKI (acute kidney injury) were observed at each time point in the two groups.  Results  No statistically significant difference was found in the general data between the two groups (P > 0.05).During the operation, two groups of the MAP, SBP (before endotracheal intubation to at the end of the operation) and DBP (one hour after the operation)comparative difference was statistically significant (|t| > 2.330, all P < 0.05). The levels of serum creatinine in both groups changed with time and the difference was statistically significant (F=188.547, P < 0.001). The values of BUN did not significantly change with time but with statistical difference between the two groups (F=1.919, P=0.125).The postoperative value of eGFR increased in both groups compared with the preoperative value but no statistical difference was observed (F=1.121, P=0.291).However, a statistical difference was found in the number of AKI between the two groups [3(3.6%) vs. 10(12.2%), χ2=4.275, P=0.039].  Conclusion  Individualised blood pressure management strategy is helpful to reduce the incidence of AKI after gastrointestinal surgery in the elderly.

     

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