Progress in the clinical treatment of oral submucosal fibrosis

WANG Feng-feng; WANG Tao; LI Chuan-zhen

doi:10.16766/j.cnki.issn.1674-4152.002558

Volume 20 Issue 7

Jul. 2022

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Article Navigation > Chinese Journal of General Practice > 2022 > 20(7): 1203-1206

WANG Feng-feng, WANG Tao, LI Chuan-zhen. Progress in the clinical treatment of oral submucosal fibrosis[J]. Chinese Journal of General Practice, 2022, 20(7): 1203-1206. doi: 10.16766/j.cnki.issn.1674-4152.002558

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WANG Feng-feng, WANG Tao, LI Chuan-zhen. Progress in the clinical treatment of oral submucosal fibrosis[J]. Chinese Journal of General Practice, 2022, 20(7): 1203-1206. doi: 10.16766/j.cnki.issn.1674-4152.002558

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Progress in the clinical treatment of oral submucosal fibrosis

doi: 10.16766/j.cnki.issn.1674-4152.002558

1.
School of Stomatology, Hainan Medical University, Haikou, Hainan 570000, China

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Received Date: 2021-10-01
Available Online: 2022-09-23

Abstract

Abstract

Oral submucosal fibrosis (OSF) is a chronic oral mucosal disease characterised by epithelial atrophy, excessive accumulation and degeneration of collagen fibres in the lamina propria and submucosa and changes in microvascular quality. It has no symptoms at the early stage. However, symptoms gradually manifest including limited mouth opening; white, stiff and inelastic mucosa; burning sensation whilst eating, especially spicy and other stimulating foods; dry mouth; and functional decline in chewing, speech and taste. OSF has a tendency to become oral cancer (7%-30%). Therefore, WHO and IARC included in the queue of potential oral malignant diseases. It's a double whammy to the patient's life and spirit. Early intervention in mild OSF patients to slow down or even stop the development of the disease has become particularly important. The prevention and treatment of OSF have been the focus of scholars in China and abroad. In recent years, researchers have been trying to explore more effective methods of prevention and treatment of OSF by means of drug therapy, hyperbaric medicine and surgical treatment. At the same time, the study of OSF pathogenesis continues to deepen. In medicine mainly around Curcuma Longa, Salvia Miltiorrhiza, aloe, placenta extract and so on, in the physiotherapy focus on Hyperbaric medicine, whilst exploring a variety of surgical procedures, both oral function and aesthetic repair of postoperative defects. At present, the effect of OSF is not good, and no definite radical therapy has been found. Individualised treatment and relief of clinical symptoms and signs are still the main ways to treat OSF. In this paper, we summarise the research progress of the treatment of OSF from three aspects of drug therapy, physical therapy and operation therapy to provide a basis for the clinical treatment of OSF by stomatologists.
- Oral submucosal fibrosis,
- Medication,
- Physiotherapy,
- Surgical operation

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References(36)

References

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Progress in the clinical treatment of oral submucosal fibrosis

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Progress in the clinical treatment of oral submucosal fibrosis

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