Volume 20 Issue 7
Jul.  2022
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(7): 1211-1214
YAN Fei-fei, XU Xu-dong, ZHANG Hai-bo, JI Ya-feng. Effects of Jianpi Tongluo Decoction on chronic obstructive pulmonary disease complicated with depression[J]. Chinese Journal of General Practice, 2022, 20(7): 1211-1214. doi: 10.16766/j.cnki.issn.1674-4152.002560
Citation: YAN Fei-fei, XU Xu-dong, ZHANG Hai-bo, JI Ya-feng. Effects of Jianpi Tongluo Decoction on chronic obstructive pulmonary disease complicated with depression[J]. Chinese Journal of General Practice, 2022, 20(7): 1211-1214. doi: 10.16766/j.cnki.issn.1674-4152.002560
shu

Effects of Jianpi Tongluo Decoction on chronic obstructive pulmonary disease complicated with depression

doi: 10.16766/j.cnki.issn.1674-4152.002560
  • 1.

    Respiratory and Intensive Care Unit, Putuo Hospital of Zhejiang, Zhoushan, Zhejiang 316100, China

Funds:

 2018ZD045

 2020C31086

  • Received Date: 2021-09-25
    Available Online: 2022-09-23
    Abstract
  •   Objective  To observe the effect of Jianpi Tongluo Decoction on the respiratory symptoms, pulmonary ventilation function and psychological state of patients with chronic obstructive pulmonary disease complicated with depression (Fipi Qixu Tanyu Zufei syndrome).  Methods  A total of 84 patients with chronic obstructive pulmonary disease complicated with depression treated in the Department of Respiratory and Critical Care Medicine of Putuo Hospital from September 2019 to September 2020 were randomly divided into observation group and control group, with 42 patients in each group. The control group was treated with conventional Western medicine, such as expectorant and antispasmodic, and the observation group was treated with Jianpi Tongluo Decoction on the basis of the control group. One course of treatment in both groups was 4 weeks, with a total of three courses of treatment. The respiratory symptoms, CAT, BODE index, HAMD, SDS and pulmonary ventilation function index (FEV1, FEV1/FVC, MIP and MEP) scores were compared. The clinical efficacy and adverse reactions of the two groups were evaluated.  Results  The total effective rates of the observation and control groups were 92.86% and 76.19%, respectively. The observation group had a significantly higher rate than the control group (P < 0.05). After treatment, the respiratory symptoms, CAT, BODE index, SDS and HAMD scores of the observation group were significantly lower than those of the control group (all P < 0.05). Meanwhile, the FEV1, FEV1/FVC, MEP and MIP index levels of the observation group were significantly higher than those of the control group (all P < 0.05). No obvious adverse reactions were observed in both groups.  Conclusion  The application of Jianpi Tongluo Decoction could improve pulmonary ventilation function, alleviate respiratory symptoms and improve depression in patients with chronic obstructive pulmonary disease complicated with depression.

     

    • FullText(HTML)
  • loading
    • References(19)
  • [1]
    梁桂林, 罗毅, 王彬, 等. 固本宣肺汤治疗稳定期慢性阻塞性肺疾病疗效及对免疫功能的影响[J]. 中华中医药学刊, 2020, 38(8): 183-186. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYHS202008044.htm

    LIANG G L, LUO Y, WANG B, et al. Clinical Efficacy of Guben Xuanfei Decoction in Treatment of Stable Chronic Obstructive Pulmonary Disease and Its Effect on Immune Function[J]. Chinese Archives of Traditional Chinese Medicine, 2020, 38(8): 183-186. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYHS202008044.htm
    [2]
    黄莹, 黄进, 董子青, 等. 桑菊清解汤治疗痰热蕴肺型慢性阻塞性肺疾病临床疗效及对免疫功能影响[J]. 中华中医药学刊, 2021, 39(7): 184-187. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYHS202107047.htm

    HUANG Y, HUANG J, DONG Z Q, et al. Effect of Sangju Qingjie Decoction on Chronic Obstructive Pulmonary Disease with Phlegm-Heat Accumulation and Its Influence on Immune Function[J]. Chinese Archives of Traditional Chinese Medicine, 2021, 39(7): 184-187. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYHS202107047.htm
    [3]
    李阳, 霍建民. 慢性阻塞性肺疾病合并症的发病率及预后研究进展[J]. 临床肺科杂志, 2018, 23(8): 1527-1531. doi: 10.3969/j.issn.1009-6663.2018.08.045

    LI Y, HUO J M. Research Progress on incidence rate and prognosis of chronic obstructive pulmonary disease[J]. Journal of Clinical Pulmonary Medicine, 2018, 23(8): 1527-1531. doi: 10.3969/j.issn.1009-6663.2018.08.045
    [4]
    陈学昂, 王明航, 李素云, 等. 肝调畅情志与慢性阻塞性肺疾病合并焦虑抑郁的相关性研究[J]. 中华中医药学刊, 2017, 35(5): 1196-1198. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYHS201705039.htm

    CHEN X A, WANG M H, LI S Y, et al. Research On Correlation of Liver Regulating Emotion and COPD with Anxiety Depression[J]. Chinese Archives of Traditional Chinese Medicine, 2017, 35(5): 1196-1198. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYHS201705039.htm
    [5]
    王晓娟, 方向阳. 慢性阻塞性肺疾病全球倡议2019: 慢性阻塞性肺疾病诊断、治疗与预防全球策略解读[J]. 中国全科医学, 2019, 22(18): 2141-2149. doi: 10.12114/j.issn.1007-9572.2019.00.064

    WANG X J, FANG X Y. Interpretation of the Global Strategy for the Diagnosis, Management, and Prevention of COPD 2019 by GOLD[J]. Chinese General Practice, 2019, 22(18): 2141-2149. doi: 10.12114/j.issn.1007-9572.2019.00.064
    [6]
    中华医学会精神科分会. 中国精神障碍分类与诊断标准(CCMD-3)[M]. 3版. 济南: 山东科学技术出版社, 2001: 83-84, 87-89.

    Psychiatric branch of Chinese Medical Association. Chinese classification and diagnostic criteria for mental disorders (CCMD-3)[M]. Version 3 Jinan: Shandong science and Technology Press, , 2001: 83-84, 87-89.
    [7]
    汤毓华, 张明园. 汉密顿抑郁量表(HAMD)[J]. 上海精神医学, 1984(2): 61-64. https://www.cnki.com.cn/Article/CJFDTOTAL-JSYI198402003.htm

    TANG Y H, ZHANG M T. Hamilton Depression Scale (HAMD)[J]. Shanghai Psychiatry, 1984(2): 61-64. https://www.cnki.com.cn/Article/CJFDTOTAL-JSYI198402003.htm
    [8]
    郑筱萸. 中药新药临床研究指导原则[M]. 北京: 中国医药科技出版社, 2002: 54-58.

    ZHENG X Y. Guiding principles for clinical research of new Chinese medicine[M]. Beijing: China Medical Science and Technology Press, 2002: 54-58
    [9]
    舒良. 自评抑郁量表[J]. 中国心理卫生杂志, 1999(增刊): 194-196. https://www.cnki.com.cn/Article/CJFDTOTAL-JBJS202112006.htm

    SHU L. Self rating Depression Scale[J]. Chinese Journal of Mental Health, 1999(Supplemen): 194-196. https://www.cnki.com.cn/Article/CJFDTOTAL-JBJS202112006.htm
    [10]
    张明园. 精神科评定量表手册[M]. 长沙: 湖南科学技术出版社, 1993: 39-42.

    ZHANG M Y. Handbook of psychiatric assessment scale[M]. Changsha: Hunan Science and Technology Press, 1993: 39-42.
    [11]
    闫香桂, 吴国芳, 黄芬, 等. 中医药治疗稳定期慢性阻塞性肺疾病研究进展[J]. 中医学报, 2016, 31(9): 1284-1288. https://www.cnki.com.cn/Article/CJFDTOTAL-HNZK201609011.htm

    YAN X G, WU G F, HUANG F, et al. Progress of TCM Treatment of Chronic Obstructive Pulmonary Disease in Stable Phase[J]. China Journal of Chinese Medicine, 2016, 31(9): 1284-1288. https://www.cnki.com.cn/Article/CJFDTOTAL-HNZK201609011.htm
    [12]
    吴娇, 王聪. 黄芪的化学成分及药理作用研究进展[J]. 新乡医学院学报, 2018, 35(9): 755-760. https://www.cnki.com.cn/Article/CJFDTOTAL-XXYX201809002.htm

    WU J, WANG C. Research Progress on chemical constituents and pharmacological effects of Astragalus membranaceus[J]. Journal of Xinxiang Medical University, 2018, 35(9): 755-760. https://www.cnki.com.cn/Article/CJFDTOTAL-XXYX201809002.htm
    [13]
    张晓娟, 左冬冬. 白术化学成分及药理作用研究新进展[J]. 中医药信息, 2018, 35(6): 101-106. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYXN201806025.htm

    HANG X J, ZUO D D. New progress in chemical constituents and pharmacological effects of Atractylodes macrocephala[J]. Information on Traditional Chinese Medicine, 2018, 35(6): 101-106. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYXN201806025.htm
    [14]
    陈梦雨, 刘伟, 侴桂新, 等. 山药化学成分与药理活性研究进展[J]. 中医药学报, 2020, 48(2): 62-66. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYXB202002016.htm

    CHEN M Y, LIU W, CHOU G X, et al. Research Progress on chemical constituents and pharmacological activities of Chinese yam[J]. Journal of Traditional Chinese Medicine, 2020, 48(2): 62-66. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYXB202002016.htm
    [15]
    邓亚羚, 任洪民, 叶先文, 等. 桔梗的炮制历史沿革、化学成分及药理作用研究进展[J]. 中国实验方剂学杂志, 2020, 26(2): 190-202. https://www.cnki.com.cn/Article/CJFDTOTAL-ZSFX202002030.htm

    DENG Y L, REN H M, YE X W, et al. Progress of Historical Evolution of Processing, Chemical Composition and Pharmacological Effect of Platycodonis Radix[J]. Chinese Journal of Experimental Traditional Medical Formulae, 2020, 26(2): 190-202. https://www.cnki.com.cn/Article/CJFDTOTAL-ZSFX202002030.htm
    [16]
    和焕香, 郭庆梅. 瓜蒌化学成分和药理作用研究进展及质量标志物预测分析[J]. 中草药, 2019, 50(19): 4808-4820. doi: 10.7501/j.issn.0253-2670.2019.19.032

    HE H X, GUO Q M. Research Progress on chemical constituents and pharmacological effects of Trichosanthes Trichosanthes and prediction and analysis of quality markers[J]. Chinese Traditional and Herbal Drugs, 2019, 50(19): 4808-4820. doi: 10.7501/j.issn.0253-2670.2019.19.032
    [17]
    卓小玉, 陈晶, 田明, 等. 麻黄的化学成分与药理作用研究进展[J]. 中医药信息, 2021, 38(2): 80-83. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYXN202102017.htm

    ZHUO X Y, CHEN J, TIAN M, et al. Research Progress on Chemical Constituents and Pharmacological Effects of Ephedra sinica[J]. Information on Traditional Chinese Medicine, 2021, 38(2): 80-83. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYXN202102017.htm
    [18]
    唐照琦, 李彪, 王秋红, 等. 胆南星的化学成分、药理作用及相关复方临床应用的研究进展[J]. 中国药房, 2020, 31(12): 1523-1527. doi: 10.6039/j.issn.1001-0408.2020.12.21

    TANG Z Q, LI B, WANG Q H, et al. Research Progress on chemical constituents, pharmacological effects and clinical application of related compounds of dannanxing[J]. China Pharmacy, 2020, 31(12): 1523-1527. doi: 10.6039/j.issn.1001-0408.2020.12.21
    [19]
    祁玉凤, 邵强, 沈兵. 慢性阻塞性肺疾病患者CAT评分与肺功能及血气分析等指标的相关性分析[J]. 中华全科医学, 2021, 19(9): 1504-1506. doi: 10.16766/j.cnki.issn.1674-4152.002097

    QI Y F, SHAO Q, SHEN B. Correlation analysis of CAT score with lung function and blood gas analysis in patients with chronic obstructive pulmonary disease[J]. Chinese Journal of General Practice, 2021, 19(9): 1504-1506. doi: 10.16766/j.cnki.issn.1674-4152.002097
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(5)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (243) PDF downloads(2) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return