Volume 20 Issue 7
Jul.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(7): 1211-1214
YAN Fei-fei, XU Xu-dong, ZHANG Hai-bo, JI Ya-feng. Effects of Jianpi Tongluo Decoction on chronic obstructive pulmonary disease complicated with depression[J]. Chinese Journal of General Practice, 2022, 20(7): 1211-1214. doi: 10.16766/j.cnki.issn.1674-4152.002560
Citation: YAN Fei-fei, XU Xu-dong, ZHANG Hai-bo, JI Ya-feng. Effects of Jianpi Tongluo Decoction on chronic obstructive pulmonary disease complicated with depression[J]. Chinese Journal of General Practice, 2022, 20(7): 1211-1214. doi: 10.16766/j.cnki.issn.1674-4152.002560
shu

Effects of Jianpi Tongluo Decoction on chronic obstructive pulmonary disease complicated with depression

doi: 10.16766/j.cnki.issn.1674-4152.002560
  • 1.

    Respiratory and Intensive Care Unit, Putuo Hospital of Zhejiang, Zhoushan, Zhejiang 316100, China

Funds:

 2018ZD045

 2020C31086

  • Received Date: 2021-09-25
    Available Online: 2022-09-23
    Abstract
  •   Objective  To observe the effect of Jianpi Tongluo Decoction on the respiratory symptoms, pulmonary ventilation function and psychological state of patients with chronic obstructive pulmonary disease complicated with depression (Fipi Qixu Tanyu Zufei syndrome).  Methods  A total of 84 patients with chronic obstructive pulmonary disease complicated with depression treated in the Department of Respiratory and Critical Care Medicine of Putuo Hospital from September 2019 to September 2020 were randomly divided into observation group and control group, with 42 patients in each group. The control group was treated with conventional Western medicine, such as expectorant and antispasmodic, and the observation group was treated with Jianpi Tongluo Decoction on the basis of the control group. One course of treatment in both groups was 4 weeks, with a total of three courses of treatment. The respiratory symptoms, CAT, BODE index, HAMD, SDS and pulmonary ventilation function index (FEV1, FEV1/FVC, MIP and MEP) scores were compared. The clinical efficacy and adverse reactions of the two groups were evaluated.  Results  The total effective rates of the observation and control groups were 92.86% and 76.19%, respectively. The observation group had a significantly higher rate than the control group (P < 0.05). After treatment, the respiratory symptoms, CAT, BODE index, SDS and HAMD scores of the observation group were significantly lower than those of the control group (all P < 0.05). Meanwhile, the FEV1, FEV1/FVC, MEP and MIP index levels of the observation group were significantly higher than those of the control group (all P < 0.05). No obvious adverse reactions were observed in both groups.  Conclusion  The application of Jianpi Tongluo Decoction could improve pulmonary ventilation function, alleviate respiratory symptoms and improve depression in patients with chronic obstructive pulmonary disease complicated with depression.

     

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