Volume 20 Issue 8
Aug.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(8): 1380-1383
KONG Shu-jun, SHI Yan, NING Yan, LI Yang. Application value of ultrafast pulse wave velocity in carotid artery elastic function detection in patients with systemic lupus erythematosus[J]. Chinese Journal of General Practice, 2022, 20(8): 1380-1383. doi: 10.16766/j.cnki.issn.1674-4152.002602
Citation: KONG Shu-jun, SHI Yan, NING Yan, LI Yang. Application value of ultrafast pulse wave velocity in carotid artery elastic function detection in patients with systemic lupus erythematosus[J]. Chinese Journal of General Practice, 2022, 20(8): 1380-1383. doi: 10.16766/j.cnki.issn.1674-4152.002602
shu

Application value of ultrafast pulse wave velocity in carotid artery elastic function detection in patients with systemic lupus erythematosus

doi: 10.16766/j.cnki.issn.1674-4152.002602

  • Department of Ultrasound Medicine, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

 KJ2020A0582

  • Received Date: 2021-10-12
    Available Online: 2022-09-26
    Abstract
  •   Objective  The elastic function of carotid artery in patients with systemic lupus erythematosus (SLE) was measured by ultrafast pulse wave velocity to explore its clinical application value.  Methods  A total of 93 patients with SLE who visited the First Affiliated Hospital of Bengbu Medical College from October 2020 to April 2021 were selected as the experimental group.According to the clinical symptoms, they were divided into SLE alone (45 cases, group B) and SLE involving multiple systems (48 cases, group C).A total of 20 healthy adults were selected as the control group (group A).Ultrafast pulse wave velocity (UFPWV) was used to quantitatively measure intima-media thickness (IMT), pulse wave velocity at the beginning of systole (PWVBS) and pulse wave velocity at the end of systole (PWVES) of the common carotid artery in all patients.The statistical results were compared and analysed.Spearman correlation analysis was used to analyse the correlation between IMT, PWVBS, PWVES and different clinical types of SLE.Finally, the ROC curve was drawn to evaluate the diagnostic efficiency.  Results  In terms of IMT level, group A was lower than group C, and the difference was statistically significant (P < 0.05);no significant difference was found amongst other groups (P>0.05).In terms of PWVBS level, group A was lower than group B and group B was lower than group C; the difference was statistically significant (F=10.068, P < 0.001).In terms of PWVES level, group A was lower than group B and group B was lower than group C; the difference was statistically significant (F=27.505, P < 0.001).The levels of ITM, PWVBS and PWVES were positively correlated with different clinical types of SLE (r=0.240, 0.442, 0.394, all P < 0.05).The areas under the ROC curve of PWVBS and PWVES were 0.794(95%CI: 0.694-0.894) and 0.960(95%CI: 0.919-1.000), respectively.  Conclusion  Carotid artery elasticity is lower in patients with SLE than in healthy adults, and its degree is more significant as the disease progresses.UFPWV can quickly measure the levels of IMT, PWVBS and PWVES in the carotid artery of patients with SLE.As a parameter index related to vascular elasticity, the results are objective and worthy of wide application in clinical practice.

     

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