Volume 20 Issue 8
Aug.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(8): 1396-1399
ZHOU Kai-ju, HE Yong-hui, WU Bi-jiao, DENG Jie-ying, CHEN Jun-hu. Analysis of monitoring results of suspected adverse event following immunization in Sanshui District, Foshan City, 2016-2019[J]. Chinese Journal of General Practice, 2022, 20(8): 1396-1399. doi: 10.16766/j.cnki.issn.1674-4152.002606
Citation: ZHOU Kai-ju, HE Yong-hui, WU Bi-jiao, DENG Jie-ying, CHEN Jun-hu. Analysis of monitoring results of suspected adverse event following immunization in Sanshui District, Foshan City, 2016-2019[J]. Chinese Journal of General Practice, 2022, 20(8): 1396-1399. doi: 10.16766/j.cnki.issn.1674-4152.002606
shu

Analysis of monitoring results of suspected adverse event following immunization in Sanshui District, Foshan City, 2016-2019

doi: 10.16766/j.cnki.issn.1674-4152.002606
  • 1.

    Center for Disease Control and prevention of Sanshui District, Foshan, Guangdong 528100, China

Funds:

 A2019199

 YGFK20210046

 1920001001287

  • Received Date: 2021-06-08
    Available Online: 2022-09-26
    Abstract
  •   Objective  To analyze the incidence of suspected adverse event following immunization (AEFI) in Sanshui District of Foshan City, to master the safety of vaccination, and to provide basis for immunization planning and management.  Methods  The AEFI cases reported in Sanshui District of Foshan City from 2016 to 2019 were collected through the China immunization planning information system, and descriptive analysis was carried out by using Excel and SPSS 17.0 software.  Results  A total of 437 cases of AEFI were reported in Sanshui District from 2016 to 2019, with an average annual reporting rate of 30.29/100 000 doses, 332 cases (73.68%) of general reactions and 76 cases (17.39%) of abnormal reactions. No vaccine quality accidents, vaccination accidents nor psychogenic reactions were reported. The sex ratio of the reported cases was 1.5 9∶ 1, with the most reported cases in the group under 1 year old, the least in the group over 7 years old and the most reported cases in the group under 1 year old. Amongst the cases, 8-month-old children accounted for the highest proportion (22.78%). The interval between vaccination and the occurrence of suspected adverse reactions after vaccination accounted for the highest proportion (64.76%). All the reported AEFI involved 27 kinds of vaccines and the top three vaccines with the highest reported incidence were 23 valent pneumonitis vaccine, leprosy vaccine and acellular DPT vaccine. The top three vaccines with abnormal reaction rate were leprosy vaccine, tetravalent HPV vaccine and 23 valent pneumonia vaccine. The top three vaccines with abnormal reaction rate were allergic reaction urticaria in 26 cases (34.21%); allergic rash in 17 cases (22.37%); and allergic reaction macular papule in 12 cases (15.79%).  Conclusion  From 2016 to 2019, all the AEFI monitoring indicators in Sanshui District of Foshan City met the requirements of the monitoring scheme and the system operated normally. The AEFI monitoring results reflect the safety of vaccines to a certain extent, especially the vaccines with the highest reported incidence. AEFI monitoring must be continuously strengthened and the sensitivity and timeliness of the monitoring system must be further improved.

     

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