Volume 20 Issue 9
Sep.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(9): 1513-1516
LI Jing, ZHE Jian-qing, WANG Jing, LIU Mei-li. Incidence and risk factors of atherosclerotic renal artery stenosis in elderly patients with refractory hypertension[J]. Chinese Journal of General Practice, 2022, 20(9): 1513-1516. doi: 10.16766/j.cnki.issn.1674-4152.002637
Citation: LI Jing, ZHE Jian-qing, WANG Jing, LIU Mei-li. Incidence and risk factors of atherosclerotic renal artery stenosis in elderly patients with refractory hypertension[J]. Chinese Journal of General Practice, 2022, 20(9): 1513-1516. doi: 10.16766/j.cnki.issn.1674-4152.002637
shu

Incidence and risk factors of atherosclerotic renal artery stenosis in elderly patients with refractory hypertension

doi: 10.16766/j.cnki.issn.1674-4152.002637

  • Department of Cardiology, the First Affiliated Hospital of Xi ' an Jiaotong University, Xi ' an, Shaanxi 710061, China

Funds:

 81800390

  • Received Date: 2022-01-22
    Available Online: 2022-11-29
    Abstract
  •   Objective  To investigate the incidence of atherosclerotic renal artery stenosis (ARAS) in elderly patients with refractory hypertension and to analyse its risk factors, to provide evidence for the early clinical diagnosis and treatment of ARAS.  Methods  The clinical data of 216 elderly patients with refractory hypertension treated in the Cardiology Department of the First Affiliated Hospital of Xi ' an Jiaotong University from February 2016 to February 2021 were retrospectively analysed. According to the results of renal artery color Doppler ultrasonography and angiography, they were divided into ARAS (n=48) and non-ARAS (n=168) groups. The clinical data of the two groups were compared, and the risk factors for ARAS were analysed.  Results  In 216 patients, 62 cases (28.70%) were diagnosed as ARAS by renal arterial ultrasonography, and 48 cases (22.22%) were confirmed as ARAS by renal arteriography. The proportions of diabetes mellitus, hyperlipidemia, peripheral vascular disease, coronary heart disease, renal insufficiency in the ARAS group were 47.92% (23/48), 68.75% (33/48), 39.58% (19/48), 54.17% (26/48) and 52.08% (25/48), respectively, significantly higher than those in the non-ASAR group [30.36% (51/168), 51.19% (86/168), 18.45% (31/168), 34.52% (58/168) and 26.79% (45/168), respectively, all P < 0.05]. Multivariate logistic-regression analysis showed that peripheral vascular disease (OR=2.651, 95% CI: 1.039-6.764) and renal insufficiency (OR=2.713, 95% CI: 1.106-6.656) were independent risk factors for ARAS in elderly patients with refractory hypertension.  Conclusion  Elderly patients with refractory hypertension have a higher incidence of ARAS, and peripheral vascular disease and renal insufficiency are independent risk factors affecting ARAS occurrence.

     

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