Volume 20 Issue 9
Sep.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(9): 1531-1534
CUI Fang-nan, TANG Xin, NIU Hong-li, JIANG Yue, ZHAO Fu-ying. Investigation and analysis of drug use status of patients with type 2 diabetes in the Haidian community of Beijing[J]. Chinese Journal of General Practice, 2022, 20(9): 1531-1534. doi: 10.16766/j.cnki.issn.1674-4152.002641
Citation: CUI Fang-nan, TANG Xin, NIU Hong-li, JIANG Yue, ZHAO Fu-ying. Investigation and analysis of drug use status of patients with type 2 diabetes in the Haidian community of Beijing[J]. Chinese Journal of General Practice, 2022, 20(9): 1531-1534. doi: 10.16766/j.cnki.issn.1674-4152.002641
shu

Investigation and analysis of drug use status of patients with type 2 diabetes in the Haidian community of Beijing

doi: 10.16766/j.cnki.issn.1674-4152.002641
  • 1.

    Internal Department, Beijing Renmin University Hospital, Beijing 100872, China

Funds:

 首发2018-3-7035

  • Received Date: 2021-05-09
    Available Online: 2022-11-29
    Abstract
  •   Objective  To investigate the drug use status of type 2 diabetes (T2DM) patients in the Haidian District of Beijing, to analyse the reasons for the concomitant medication and the problem of polypharmacy, and to provide the basis for clinical rational drug use.  Methods  Patients who established the chronic disease file of T2DM in the community health service of the People ' s University of China and had been regularly visited for 6 months or longer between January 1, 2020 and December 31, 2020 were selected. The basic information of patients, the time of diagnosis of T2DM, comorbid diseases, and current medication were recorded.  Results  A total of 467 patients with T2DM were included in this study. The ratio of male to female was 1∶ 1.02, the age was 37 - 98 years, the course of disease was 0.5-37.5 years, and the medication was 5 (4, 7) species. Amongst them, 419 patients used drug intervention to control blood glucose, and 41.77% (175/419) patients used single-drug hypoglycaemic therapy. A total of 72.55% (304/419) patients used metformin containing hypoglycaemic regimen, 50.84% (213/419) patients were treated with α-glucosidase inhibitor, 23.40% (98/419) patients used sulphonylurea, 22.91% (96/419) patients used insulin, and 5.73% (24/419) patients used dipeptidyl peptidase 4 inhibitor. A total of 70.45% (329/467) patients used lipid-lowering therapy, 54.39% (254/467) patients continued to use antiplatelet aggregation drugs therapy, and 74.73% (349/467) patients used a combination of antihypertensive drugs. A total of 281 patients (60.17%) took five or more drugs at the same time for a long time. With prolonged disease course, the number of combined medications increased gradually, and the number of concomitant medications was positively correlated with the duration of diabetes (r=0.177, P < 0.001).  Conclusion  In the Haidian community of Beijing, T2DM patients with multiple-drug use are common, and hidden medical risks exist. Doctors should strengthen the management of patients, optimise the medication plan, and ensure medical safety.

     

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