Volume 20 Issue 9
Sep.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(9): 1541-1544
LI Xin, XIE Ji-cheng, WANG Jing, PANG Jian-xin, WU Ling, JI Wen-bin. The application value of magnetic resonance MRS, DWI and SWI sequences in the grading diagnosis of glioma[J]. Chinese Journal of General Practice, 2022, 20(9): 1541-1544. doi: 10.16766/j.cnki.issn.1674-4152.002644
Citation: LI Xin, XIE Ji-cheng, WANG Jing, PANG Jian-xin, WU Ling, JI Wen-bin. The application value of magnetic resonance MRS, DWI and SWI sequences in the grading diagnosis of glioma[J]. Chinese Journal of General Practice, 2022, 20(9): 1541-1544. doi: 10.16766/j.cnki.issn.1674-4152.002644
shu

The application value of magnetic resonance MRS, DWI and SWI sequences in the grading diagnosis of glioma

doi: 10.16766/j.cnki.issn.1674-4152.002644
  • 1.

    Department of Radiology, Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang 317000, China

  • 2.

    Department of Radiology, Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang 317000, China

Funds:

 82102114

 2019KY777

 1902KY30

  • Received Date: 2020-05-06
    Available Online: 2022-11-29
    Abstract
  •   Objective  To investigate the application value of 1H-magnetic resonance spectroscopy (1H-MRS), diffusion weighted imaging (DWI) and susceptibility weighted imaging (SWI) in the grading diagnosis of glioma.  Methods  Seventy-six cases of glioma confirmed by surgery or biopsy in our hospital were collected. According to the 2016 Edition of the WHO classification standard of the central nervous system tumors, the cases were divided into low-level group of glioma (Ⅰ-Ⅱ, 31 cases) and the high-level group of glioma (Ⅲ-Ⅳ, 45 cases). The original data were processed with the Functool software of GE ADW 4.5 workstation. MRS, DWI and SWI mapping software were selected to measure the main metabolites including choline (CHO), creatine (CR) and N-acetylaspartate (NAA) in the tumor parenchymal area of MRS and calculated the ratio, apparent diffusion coefficient (ADC) and intertumoral susceptibility signal (ITSS). Statistical analysis was performed on the results of the two groups with Mann-Whitney U Test.  Results  In the low-grade glioma group and high-grade glioma group, the Cho/NAA ratios were 1.780 and 4.390, the Cho/Cr ratios were 1.920 and 3.560, and the NAA/Cr ratios were 0.930 and 0.780, respectively. ADC values were 1.730 ×10-3mm2/s and 1.030×10-3mm2/s, ITSS scores were 1.0 and 2.0, respectively. The differences of Cho/NAA, Cho/Cr, NAA/Cr, ADC and ITSS scores were statistically significant between two groups (all P < 0.001).  Conclusion  MR multimodal imagings (MRS, DWI and SWI) show important application value in the grading diagnosis of glioma.

     

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