Sensitization patterns of inhaled allergens in adults self-reported allergic rhinitis in Zhengzhou area

DU Wen-jin; ZHANG Qiu-xing; ZHANG Wen-chao; WANG Si-qin

doi:10.16766/j.cnki.issn.1674-4152.002676

Volume 20 Issue 10

Oct. 2022

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Article Navigation > Chinese Journal of General Practice > 2022 > 20(10): 1675-1677

DU Wen-jin, ZHANG Qiu-xing, ZHANG Wen-chao, WANG Si-qin. Sensitization patterns of inhaled allergens in adults self-reported allergic rhinitis in Zhengzhou area[J]. Chinese Journal of General Practice, 2022, 20(10): 1675-1677. doi: 10.16766/j.cnki.issn.1674-4152.002676

Citation:

DU Wen-jin, ZHANG Qiu-xing, ZHANG Wen-chao, WANG Si-qin. Sensitization patterns of inhaled allergens in adults self-reported allergic rhinitis in Zhengzhou area[J]. Chinese Journal of General Practice, 2022, 20(10): 1675-1677. doi: 10.16766/j.cnki.issn.1674-4152.002676

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Sensitization patterns of inhaled allergens in adults self-reported allergic rhinitis in Zhengzhou area

doi: 10.16766/j.cnki.issn.1674-4152.002676

Department of Allergy, Henan Provincial People' s Hospital, People' s Hospital of Zhengzhou University, People' s Hospital of Henan University, Zhengzhou, Henan 450003, China

Funds:

320.6750.2022-02-7

Received Date: 2022-06-02
Available Online: 2022-11-30

Abstract

Abstract

Objective To investigate the sensitization spectrum of adult self-reported allergic rhinitis (AR) patients in Zhengzhou area, analyze the differences of aeroallergen sensitization rates in different age groups, genders and years, and to provide reference for clinical diagnosis and treatment of AR. Methods Seventeen kinds of inhaled allergen reagents were used to conduct skin prick test (SPT), which was performed in 2 305 adult self-reported AR patients from January 2019 to December 2021 in Henan Provincial People' s Hospital. The distribution of allergens in different genders, ages and years was compared, and the positive rate was analyzed. Results The positive rate of SPT in 2 305 AR patients was 77.09%, which was often complicated with multiple allergens, among them, 1 137 patients (49.33%) were positive for 4 or more allergens. The top 5 allergen positive rates were pollen of dust mite (42.78%), house dust mite (38.61%), Platanus acerifolia pollen (35.27%), Artemisia pollen (34.27%) and Humulus scandens pollen (31.63%). The SPT positive rate of patients aged 18-30 years was the highest (91.84%), and the positive rate decreased with the increase of age. The positive rate of dust mite, house dust mite, Rape pollen and Humulus scandens pollen were statistically significant differences among different genders (all P < 0.05). From 2019 to 2021, the positive rate of dust mites and house dust mites were increased year by year, while the positive rate of Platanus acerifolia pollen, Artemisia pollen and Humulus scandens pollen were decreased year by year. Conclusion AR patients are more likely to be allergic to 4 or more inhaled allergens. The positive rate of SPT was highest in 18-30 years old. Among the common allergens of self-reported AR in adults in Zhengzhou, dust mite, household dust mite, Platanus acerifolia pollen, Artemisia pollen and Humulus scandens pollen are the most common allergens.
- Allergic rhinitis,
- Inhaled allergen,
- Skin prick test,
- Sensitization

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References(20)

References

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Sensitization patterns of inhaled allergens in adults self-reported allergic rhinitis in Zhengzhou area

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