Volume 20 Issue 10
Oct.  2022
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LI Yan-hui, ZHAO Chen-xi, CHEN Ming, YANG Shuang-ling, XUE Xian-jun. Application value of ultrasound in adult patients with thyroid nodules ≥3 cm[J]. Chinese Journal of General Practice, 2022, 20(10): 1742-1745. doi: 10.16766/j.cnki.issn.1674-4152.002693
Citation: LI Yan-hui, ZHAO Chen-xi, CHEN Ming, YANG Shuang-ling, XUE Xian-jun. Application value of ultrasound in adult patients with thyroid nodules ≥3 cm[J]. Chinese Journal of General Practice, 2022, 20(10): 1742-1745. doi: 10.16766/j.cnki.issn.1674-4152.002693

Application value of ultrasound in adult patients with thyroid nodules ≥3 cm

doi: 10.16766/j.cnki.issn.1674-4152.002693
Funds:

 LHGJ20191377

  • Received Date: 2021-09-21
    Available Online: 2022-11-30
  •   Objective  To clarify the difference of ultrasound (US) images between ≥3.0 cm thyroid nodules (TNS) and < 3.0 cm TNS, and to explore the application value of US in patients with ≥3.0 cm thyroid nodules.  Methods  From March 2017 to August 2019, 545 patients underwent US examination and thyroid surgery in the Shenma Medical Group General Hospital, Sanquan College, and Oilfield General Hospital of Puyang City were selected and divided into the large nodule group (115 cases, 152 nodules) and small nodule group (352 cases, 417 nodules) according to the maximum diameter of thyroid nodules. The large nodule group comprised patients with thyroid nodules ≥ 3.0 cm, whereas patients with thyroid nodules < 3.0 cm were in the small nodule group. The clinical and US imaging features were compared between the two groups.  Results  (1) The microcalcification rate (28.94%), hypoechoic rate (40.13%) and irregular shape rate (13.82%) in patients with large nodules were higher than those in patients with small nodules (18.94%, 7.19% and 3.36%, respectively, all P < 0.05). The cystic structure rate (9.21%), mixed nodule rate (30.26%), hyperechoic rate (30.92%) and perinodal vascular rate (4.61%) in patients with large nodules were lower than those in patients with small nodules (18.94%, 48.44%, 42.93% and 13.43%, respectively, all P < 0.05). (2) No significant difference was found between the diagnosis results of TI-RADS classification of large thyroid nodules and small thyroid nodules (P>0.05). (3) The correct rate of US in diagnosing large thyroid nodules was 74.3% (113/152). Large nodules were the risk factors of malignant thyroid nodules (OR=2.674, 95% CI: 1.116-6.405, P=0.027).  Conclusion  There are differences in US characteristics between patients with TNS ≥3.0 cm and patients with TNS < 3.0 cm. Compared with small thyroid nodules, large thyroid nodules have a higher risk of malignant transformation.

     

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