Volume 20 Issue 10
Oct.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(10): 1751-1754
WU Wan, LI Yi-wen, LIANG Bing, WEN Ting-yu, YANG Miao, WANG Wei, WANG Tao. Analysis of the current status of FRAXⓇ application in evaluating osteoporotic fractures in China[J]. Chinese Journal of General Practice, 2022, 20(10): 1751-1754. doi: 10.16766/j.cnki.issn.1674-4152.002695
Citation: WU Wan, LI Yi-wen, LIANG Bing, WEN Ting-yu, YANG Miao, WANG Wei, WANG Tao. Analysis of the current status of FRAXⓇ application in evaluating osteoporotic fractures in China[J]. Chinese Journal of General Practice, 2022, 20(10): 1751-1754. doi: 10.16766/j.cnki.issn.1674-4152.002695
shu

Analysis of the current status of FRAXⓇ application in evaluating osteoporotic fractures in China

doi: 10.16766/j.cnki.issn.1674-4152.002695
  • 1.

    Department of General Medicine, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

 SK2019A0179

  • Received Date: 2021-09-11
    Available Online: 2022-11-30
    Abstract
  • The fracture risk assessment tool (FRAXⓇ) was released in 2008 to provide country-specific algorithms. It was established on the basis of patient clinical risk factors (such as age, gender, height, weight, history of osteoporosis fracture, history of hip fracture in parents, history of smoking, history of excessive drinking, application history of adrenal cortical hormone, history of rheumatoid arthritis and other history of secondary osteoporosis and femoral neck bone mineral density) to assess the probability of hip fracture and major osteoporotic fracture (such as vertebral, hip, forearm or proximal humeral) in the next 10 years. When FRAXⓇ was launched, only eight national and regional models were available to choose from. At present, 71 models are available for 66 countries. The number of users is more than 80% of the world population, and FRAXⓇ is widely used in the United Kingdom, the United States, Japan, Sweden and other countries. The initial intervention threshold of FRAXⓇ was defined on the basis of nine large population cohorts, eight of which were Caucasian and one from Japanese population. However, FRAXⓇ is rarely studied and applied in China and according to the intervention thresholds recommended by the current guidelines, FRAXⓇ may underestimate the risk of fractures in the Chinese population, especially major osteoporotic fractures. Therefore, some scholars are trying to improve the application of FRAXⓇ to explore intervention thresholds suitable for Chinese population. This paper analysed the application status and adjustment plan of FRAXⓇ in China in recent years through evaluation of hip fracture and major osteoporotic fracture with FRAXⓇ for its better applicability in China and to better predict fracture risk, identify people at high risk of fracture and early intervention in time and reduce the incidence of fractures.

     

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