Volume 20 Issue 10
Oct.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(10): 1792-1796
WANG Xue, WANG Yu-he, GAO Shan, HOU Ting-ting, HONG Lei, ZHU Yu-lin, ZHANG Yong. Evaluation and implementation of an antimicrobial stewardship checklist in a respiratory ICU ward in a tertiary teaching hospital[J]. Chinese Journal of General Practice, 2022, 20(10): 1792-1796. doi: 10.16766/j.cnki.issn.1674-4152.002704
Citation: WANG Xue, WANG Yu-he, GAO Shan, HOU Ting-ting, HONG Lei, ZHU Yu-lin, ZHANG Yong. Evaluation and implementation of an antimicrobial stewardship checklist in a respiratory ICU ward in a tertiary teaching hospital[J]. Chinese Journal of General Practice, 2022, 20(10): 1792-1796. doi: 10.16766/j.cnki.issn.1674-4152.002704
shu

Evaluation and implementation of an antimicrobial stewardship checklist in a respiratory ICU ward in a tertiary teaching hospital

doi: 10.16766/j.cnki.issn.1674-4152.002704
  • 1.

    Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

 1804h08020287

  • Received Date: 2021-12-18
    Available Online: 2022-11-30
    Abstract
  •   Objective  To analyse the consumption of antimicrobials in the respiratory intensive care unit (RICU) before and after the implementation of an antimicrobial stewardship checklist and evaluate the clinical application value of the antimicrobial stewardship checklist.  Methods  An antimicrobial stewardship checklist was designed according to RICU working practice. The antimicrobial-related data of all inpatients in the RICU of the First Affiliated Hospital of Bengbu Medical College from January 2013 to December 2019 were retrospectively analysed. Inpatients before the implementation of antimicrobial checklist management from January 2013 to December 2015 were set as the control group, and the remaining inpatients from January 2017 to December 2019, who were subject to antimicrobial checklist management, were set as the intervention group. The frequency of intensity of antibiotics use density (AUD), pathogenic test results, hospitalization improvement rate and length of RICU stay were calculated and analysed for both groups.  Results  After the implementation of the antimicrobial management checklist, the AUD values of the control group (n=329) and the intervention group (n=550) were 207.51 DDD/(100 people·day) and 146.21 DDD/(100 people·day), respectively. For the control group and the intervention group, the drug use rates were 67.99% (223/328) and 25.83% (124/480, χ2=141.313, P < 0.001), respectively; the combined drug ratios were 94.82% (311/328) and 65.21% (313/480, χ2=97.132, P < 0.001), respectively; and the rates of microbial testing before antimicrobial use were 92.68% (304/328) and 97.50% (468/480, χ2=10.621, P=0.001), respectively. The length of hospital stay decreased from 8 (6, 13) days to 8 (5, 12) days, and the difference was statistically significant (Z=-1.965, P=0.049).  Conclusion  The implementation of an antimicrobial stewardship checklist can help in reducing the intensity of antimicrobial drug use and reduce the frequency of combined use and high-grade use of antimicrobials, which is helpful to standardise the antimicrobial application and has high value in clinical application.

     

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