Volume 20 Issue 11
Nov.  2022
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ZHANG Wen-yu, WU Huan. Clinical observation of Chen' s Menstrual Conditioning Soup combined with femostone on premature ovarian failure of liver and kidney Yin deficiency syndrome[J]. Chinese Journal of General Practice, 2022, 20(11): 1934-1937. doi: 10.16766/j.cnki.issn.1674-4152.002739
Citation: ZHANG Wen-yu, WU Huan. Clinical observation of Chen' s Menstrual Conditioning Soup combined with femostone on premature ovarian failure of liver and kidney Yin deficiency syndrome[J]. Chinese Journal of General Practice, 2022, 20(11): 1934-1937. doi: 10.16766/j.cnki.issn.1674-4152.002739
shu

Clinical observation of Chen' s Menstrual Conditioning Soup combined with femostone on premature ovarian failure of liver and kidney Yin deficiency syndrome

doi: 10.16766/j.cnki.issn.1674-4152.002739
  • 1.

    Department of Gynecology, the Third Affiliated Hospital of Zhejiang University of Traditional Chinese

Funds:

 Y201942331

 2019ZB066

  • Received Date: 2021-12-29
    Available Online: 2022-12-30
    Abstract
  •   Objective  To retrospectively analyses the clinical curative effect of Chen' s Menstrual Conditioning Soup combined with femoston on premature ovarian failure of liver and kidney Yin deficiency syndrome.  Methods  Forty cases of premature ovarian failure with Yin deficiency of liver and kidney in the Third Affiliated Hospital of Zhejiang University of Traditional Chinese Medicine were retrospectively analysed from January 2019 to January 2021. According to the treatment methods, they were divided into femoston treatment group (control group, n=17) and femoston combined with Chen' s Menstrual Conditioning Soup treatment group (observation group, n=23). The treatment effect was observed after 6 months.  Results  After treatment, the scores of TCM syndromes in the observation group were lower than those in the control group (all P < 0.05). The therapeutic effect of the observation group was better than that of the control group (Z=-2.455, P < 0.05). The levels of serum follicle stimulating hormone and luteinizing hormone in the observation group were (19.21±4.57) IU/L and (20.44±3.10) IU/L, respectively, which were lower than those in the control group [(22.78±4.69) IU/L, (23.17±3.44) IU/L, all P < 0.05]. The level of estradiol (E2) in the observation group was (69.22±12.39) pmol/L, which was higher than that in the control group [(60.98±11.22) pmol/L, P < 0.05]. The mean ovarian volume, number of antral follicles and peak systolic blood flow velocity of ovarian artery in the observation group were higher than those in the control group, and the resistance index and acceleration time were lower than those in the control group (all P < 0.05).  Conclusion  Chen' s Menstrual Conditioning Soup combined with femostone has a remarkable effect on premature ovarian failure of liver and kidney Yin deficiency syndrome, and it can effectively alleviate clinical symptoms, promote the recovery of sex hormone level and improve ovarian function.

     

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